Collect. Czech. Chem. Commun.
1995, 60, 1386-1389
https://doi.org/10.1135/cccc19951386
A Facile Synthesis of 6-Cyanopurine Bases
Michal Hocek and Antonín Holý
Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 166 10 Prague 6, Czech Republic
Individual author index pages
Other CCCC articles of these authors
- Zdeněk Zídek, Antonín Holý, Daniela Franková, Evžen Buchar and Zdeněk Jiřička
Inhibition of rat adjuvant-induced arthritis by 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA; Adefovir): Immunological, biochemical and hematological correlates
Symposium Series 1999, Vol. 2, pp. 180–185 [Abstract]
Published online 2016-05-09 20:59:34 - Gabriel Birkuš, Ivan Votruba, Antonín Holý and Berta Otová
HPMPApp as a substrate toward replicative DNA polymerases α, δ and ε
Symposium Series 1999, Vol. 2, pp. 289–293 [Abstract]
Published online 2016-05-08 23:33:04 - Romana Krejčová, Květoslava Horská, Ivan Votruba and Antonín Holý
Phosphorylation of enantiomers of HPMPG
Symposium Series 1999, Vol. 2, pp. 286–288 [Abstract]
Published online 2016-05-08 23:32:58 - Petr Alexander, Antonín Holý and Milena Masojídková
Synthesis of N3-substituted isoguanine derivatives of acyclic nucleotide phosphonates
Symposium Series 1999, Vol. 2, pp. 263–265 [Abstract]
Published online 2016-05-08 23:32:12 - Zlatko Janeba and Antonín Holý
Synthesis of 8-hydroxy and 8-mercapto derivatives of acyclic adenine nucleoside and nucleotide analogs. Alkylation of 8-substituted adenines
Symposium Series 1999, Vol. 2, pp. 260–262 [Abstract]
Published online 2016-05-08 23:32:05 - Dana Hocková, Milena Masojídková and Antonín Holý
Significant influence of (N,N-dimethylamino)methylene protection at N6-position of adenine on regioselectivity of alkylations: Selective synthesis of 7-substituted adenines
Symposium Series 1999, Vol. 2, pp. 257–259 [Abstract]
Published online 2016-05-08 23:31:57 - Michal Česnek, Michal Hocek and Antonín Holý
Cross-coupling reactions of 2-amino-6-halopurine derivatives with organometallic reagents leading to 6-alkylated purine acyclic nucleotide analogues
Symposium Series 1999, Vol. 2, pp. 255–256 [Abstract]
Published online 2016-05-08 23:31:50 - Miroslav Otmar, Ivan Votruba and Antonín Holý
An alternative synthesis of HPMPC and HPMPA diphosphoryl derivatives
Symposium Series 1999, Vol. 2, pp. 252–254 [Abstract]
Published online 2016-05-08 23:31:40 - Miroslav Otmar, Milena Masojídková and Antonín Holý
Synthesis of acyclic 9-deazanucleosides: 9-(2,3-Dihydroxypropyl)-9-deazahypoxanthine
Symposium Series 1999, Vol. 2, pp. 57–59 [Abstract]
Published online 2016-05-08 20:40:59 - Michal Hocek, Martina Havelková, Dalimil Dvořák, Antonín Holý and Ivan Votruba
Synthesis of 6-phenylpurine bases and nucleosides by Suzuki–Miyaura cross-coupling reactions of 6-chloropurines with substituted phenylboronic acids
Symposium Series 1999, Vol. 2, pp. 27–30 [Abstract]
Published online 2016-05-08 20:40:17 - Pavel Turek, Michal Hocek and Martin Kotora
[2+2+2]-co-Cyclotrimerization of 6-alkynylpurines with diynes: A method for preparation 6-arylpurines
Symposium Series 2002, Vol. 5, pp. 389–390 [Abstract]
Published online 2016-01-25 20:52:00 - Marcela Krečmerová, Miloš Buděšínský and Antonín Holý
Synthesis of optically pure N6-alkyl derivatives of (2R)-3-(adenin-9-yl)-2-hydroxypropanoic acid and related compounds
Symposium Series 2002, Vol. 5, pp. 358–360 [Abstract]
Published online 2016-01-25 20:50:59 - Hubert Hřebabecký, Michal Šála, Milena Masojídková and Antonín Holý
Synthesis of racemic 2-hydroxy-4- and 2-hydroxy-5-(hydroxymethyl)cyclohexyl nucleoside analogues
Symposium Series 2002, Vol. 5, pp. 332–334 [Abstract]
Published online 2016-01-25 20:42:39 - Dana Hocková, Antonín Holý and Milena Masojídková
Synthesis of acyclic nucleotide analogues derived from 5-substituted 2,4-diamino-6-hydroxypyrimidines
Symposium Series 2002, Vol. 5, pp. 326–327 [Abstract]
Published online 2016-01-25 20:42:30 - Michal Hocek
Synthesis of carba-analogues of myoseverin
Symposium Series 2002, Vol. 5, pp. 324–325 [Abstract]
Published online 2016-01-25 20:42:22 - Michal Česnek, Antonín Holý and Milena Masojídková
Isomeric guanidinopurine nucleosides and their analogues
Symposium Series 2002, Vol. 5, pp. 306–307 [Abstract]
Published online 2016-01-25 20:41:57 - Petr Čapek, Miroslav Otmar, Milena Masojídková and Antonín Holý
Cross-coupling reactions of 2,6-dichloro-9-deazapurine
Symposium Series 2002, Vol. 5, pp. 304–305 [Abstract]
Published online 2016-01-25 20:41:51 - Miroslav Otmar, Milena Masojídková, Ivan Votruba and Antonín Holý
Synthesis and cytostatic activity of 2,6-diamino-9-benzyl-9-deazapurine and related compounds
Symposium Series 2002, Vol. 5, pp. 38–39 [Abstract]
Published online 2016-01-25 20:38:21 - Michal Hocek, Dalimil Dvořák and Martina Havelková
Covalently linked purine dimers or trimers and purine–pyrimidine conjugates – analogues of nucleobase-pairs or triplets
Symposium Series 2002, Vol. 5, pp. 36–37 [Abstract]
Published online 2016-01-25 20:38:15 - Antonín Holý
Synthetic approaches to "opened-ring" acyclic nucleoside phosphonates – novel type of antivirals
Symposium Series 2002, Vol. 5, pp. 27–35 [Abstract]
Published online 2016-01-25 20:38:08 - Silvie Vrbovská and Antonín Holý
Novel type of bis-phosphonate congeners of acyclic nucleoside phosphonates
Symposium Series 2005, Vol. 7, pp. 487–488 [Abstract]
Published online 2015-11-08 11:59:01 - Milan Vrabel, Ivan Rosenberg and Michal Hocek
Synthesis of modified nucleosides and oligonucleotides bearing bipyridine or phenanthroline ligands
Symposium Series 2005, Vol. 7, pp. 485–486 [Abstract]
Published online 2015-11-08 11:58:56 - Markéta Schinkmanová, Ivan Votruba and Antonín Holý
N6-methyl-AMP hydrolase activates N6-substituted purine ANPs
Symposium Series 2005, Vol. 7, pp. 463–464 [Abstract]
Published online 2015-11-08 11:58:20 - Michal Šála, Hubert Hřebabecký, Milena Masojídková and Antonín Holý
Synthesis of novel racemic conformationally locked carbocyclic nucleosides
Symposium Series 2005, Vol. 7, pp. 461–462 [Abstract]
Published online 2015-11-08 11:58:15 - Petr Novák, Michal Hocek and Martin Kotora
Synthesis of C-arylribosides by catalytic [2+2+2]-cyclotrimerization reaction
Symposium Series 2005, Vol. 7, pp. 445–446 [Abstract]
Published online 2015-11-08 11:57:49 - Radim Nencka, Ivan Votruba, Hubert Hřebabecký, Eva Tloušťová, Květa Horská, Milena Masojídková and Antonín Holý
Design and synthesis of 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase
Symposium Series 2005, Vol. 7, pp. 441–442 [Abstract]
Published online 2015-11-08 11:57:40 - Martin Kuchař and Michal Hocek
Synthesis of purines bearing functionalized C-substituents by nucleophilic additions to 6-ethynyl- or 6-vinylpurines
Symposium Series 2005, Vol. 7, pp. 423–424 [Abstract]
Published online 2015-11-08 11:57:11 - Kateřina Hořejší, Radek Pohl and Antonín Holý
Tricyclic etheno analogs of purines derived from 2-amino-6-chloropurine
Symposium Series 2005, Vol. 7, pp. 403–404 [Abstract]
Published online 2015-11-08 11:56:30 - Petra Doláková, Milena Masojídková and Antonín Holý
Synthesis and properties of chiral open-ring acyclic nucleoside bisphosphonates
Symposium Series 2005, Vol. 7, pp. 395–396 [Abstract]
Published online 2015-11-08 11:56:15 - Šárka Chalupová and Antonín Holý
Synthesis of N4-substituted derivatives of (S)-1-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (HPMPC, Cidofovir, Vistide©)
Symposium Series 2005, Vol. 7, pp. 387–388 [Abstract]
Published online 2015-11-08 11:56:01 - Miroslav Hájek, Naděžda Matulová, Ivan Votruba, Antonín Holý and Eva Tloušťová
Acyclic nucleoside phosphonates and human telomerase inhibition
Symposium Series 2005, Vol. 7, pp. 373–374 [Abstract]
Published online 2015-11-08 11:55:35 - Marcela Krečmerová and Antonín Holý
Synthesis of C-5 substituted HPMPC (cidofovir) derivatives
Symposium Series 2005, Vol. 7, pp. 287–290 [Abstract]
Published online 2015-11-08 11:54:07 - Miroslav Otmar, Milena Masojídková and Antonín Holý
Acyclic nucleoside phosphonates containing O-substituted hydroxypyridineamines and diamines as nucleobases
Symposium Series 2005, Vol. 7, pp. 283–285 [Abstract]
Published online 2015-11-08 11:54:02 - Pavel Turek, Michal Hocek and Martin Kotora
Cocyclotrimerization of 6-alkynylpurines with diynes as a novel approach to biologically active 6-arylpurines
Symposium Series 2005, Vol. 7, pp. 279–282 [Abstract]
Published online 2015-11-08 11:53:57 - Jan Štambaský, Pavel Kočovský and Michal Hocek
Towards a novel approach to C-nucleosides
Symposium Series 2005, Vol. 7, pp. 277–278 [Abstract]
Published online 2015-11-08 11:53:52 - Michal Česnek and Antonín Holý
Biological activity of selected guanidinopurines
Symposium Series 2005, Vol. 7, pp. 249–251 [Abstract]
Published online 2015-11-08 11:53:17 - Peter Šilhár, Radek Pohl, Ivan Votruba and Michal Hocek
Synthesis and transformations of 6-(hydroxymethyl)purines
Symposium Series 2005, Vol. 7, pp. 221–224 [Abstract]
Published online 2015-11-08 11:52:45 - Petr Čapek and Michal Hocek
Synthesis of (purin-6-yl)amino acids
Symposium Series 2005, Vol. 7, pp. 217–220 [Abstract]
Published online 2015-11-08 11:52:40 - Michal Hocek and Dana Hocková
Regioselective cross-coupling reactions in the synthesis of multisubstituted purine bases and nucleosides
Symposium Series 2005, Vol. 7, pp. 213–216 [Abstract]
Published online 2015-11-08 11:52:35 - Agnieszka Bzowska, Katarzyna Stępniak, Monika Olasek, Maciej Długosz, Beata Wielgus-Kutrowska, Jan Antosiewicz, Antonín Holý, Gertraud Koellner, Albrecht Stroh, Grzegorz Raszewski, Thomas Steiner and Joachim Frank
Attempts to differentiate subunits of trimeric and hexameric purine nucleoside phosphorylases by crystal structure and solution studies using purine bases, modified purine nucleosides, acyclonucleosides and their phosphonate analogues
Symposium Series 2005, Vol. 7, pp. 133–142 [Abstract]
Published online 2015-11-08 11:51:21 - Martin Štefko and Michal Hocek
A modular methodology for the synthesis of 3- and 4-substituted benzene and aniline C-ribonucleosides
Symposium Series 2008, Vol. 10, pp. 455–456 [Abstract]
Published online 2015-10-30 18:45:05 - Ondřej Sedláček, Radek Pohl and Antonín Holý
Synthesis of 8-C-substituted 2,6-diaminopurine acyclic nucleoside phosphonates by Negishi cross-coupling
Symposium Series 2008, Vol. 10, pp. 449–450 [Abstract]
Published online 2015-10-30 18:44:50 - Jan Riedl and Michal Hocek
Synthesis of modified fluorescent nucleosides
Symposium Series 2008, Vol. 10, pp. 442–443 [Abstract]
Published online 2015-10-30 18:44:40 - David Mařák, Miroslav Otmar, Martin Dračínský, Ivan Votruba and Antonín Holý
Nucleosides and nucleotides containing 8-aza-7,9-dideazaxanthine
Symposium Series 2008, Vol. 10, pp. 426–428 [Abstract]
Published online 2015-10-30 18:44:11 - Lubica Kalachova and Michal Hocek
Synthesis of modified nucleosides and nucleoside triphosphates bearing oligopyridine ligands
Symposium Series 2008, Vol. 10, pp. 366–368 [Abstract]
Published online 2015-10-30 18:42:13 - Petr Jansa, Martin Dračínský and Antonín Holý
Efficient synthesis of "open-ring, close-ring" acyclic nucleoside phosphonates
Symposium Series 2008, Vol. 10, pp. 360–361 [Abstract]
Published online 2015-10-30 18:42:02 - Zbyněk Hasník and Michal Hocek
Synthesis of (purin-6-yl)acetates and their transformations
Symposium Series 2008, Vol. 10, pp. 352–354 [Abstract]
Published online 2015-10-30 18:41:46 - Martin Dračínský, Marcela Krečmerová and Antonín Holý
Study of chemical stability of antivirally active 5-azacytosine acyclic nucleoside phosphonates using NMR spectroscopy
Symposium Series 2008, Vol. 10, pp. 338–340 [Abstract]
Published online 2015-10-30 18:41:11 - Petra Doláková, Martin Dračínský and Antonín Holý
Synthesis of acyclic nucleoside diphosphate mimics
Symposium Series 2008, Vol. 10, pp. 336–337 [Abstract]
Published online 2015-10-30 18:41:05 - Igor Čerňa and Michal Hocek
Direct C–H arylation of purines and purine nucleosides
Symposium Series 2008, Vol. 10, pp. 327–329 [Abstract]
Published online 2015-10-30 18:40:48 - Jiří Blažek, Antonín Holý, Petra Lipovová, Zita Purkrtová and Blanka Králová
Analogs of pyrimidin-2-one nucleosides and their enzymatic galactosylation
Symposium Series 2008, Vol. 10, pp. 322–324 [Abstract]
Published online 2015-10-30 18:40:37 - Ondřej Baszczyňski, Antonín Holý, Martin Dračínský and Blanka Klepetářová
Synthesis of N9-(3-fluoro-2-phosphonomethoxypropyl) (FPMP) derivatives of N6-substituted adenines and 2,6-diaminopurines
Symposium Series 2008, Vol. 10, pp. 315–316 [Abstract]
Published online 2015-10-30 18:40:22 - Jan Bárta and Michal Hocek
Modular synthesis of 5-substituted thiophen-2-yl C-2'-deoxyribonucleosides
Symposium Series 2008, Vol. 10, pp. 313–314 [Abstract]
Published online 2015-10-30 18:40:16 - Radim Nencka, Hubert Hřebabecký, Ivan Votruba, Martin Dračínský and Antonín Holý
Metalation of 6-halo-2,4-dimethoxypyrimidines as the key step for the synthesis of biologicaly active compounds
Symposium Series 2008, Vol. 10, pp. 249–253 [Abstract]
Published online 2015-10-30 18:38:37 - Karel Pomeisl, Antonín Holý, Ivan Votruba, Radim Nencka and Radek Pohl
Facile syntheses of pyrimidine acyclic nucleoside phosphonates and their potential evaluation for biomedical applications
Symposium Series 2008, Vol. 10, pp. 201–205 [Abstract]
Published online 2015-10-30 18:37:39 - Marcela Krečmerová, Antonín Holý, Alois Pískala, Graciela Andrei, Robert Snoeck, Jan Balzarini and Erik De Clercq
New antiviral agent, 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: esters and base-modified derivatives
Symposium Series 2008, Vol. 10, pp. 196–200 [Abstract]
Published online 2015-10-30 18:37:33 - Milan Vrabel and Michal Hocek
Synthesis of modified nucleosides, nucleotides and oligonucleotides bearing metal complexes
Symposium Series 2008, Vol. 10, pp. 182–185 [Abstract]
Published online 2015-10-30 18:37:15 - Hana Cahová, Luděk Havran, Petra Brázdilová, Hana Pivoňková, Miroslav Fojta and Michal Hocek
Aminophenyl- and nitrophenyl-labeled DNA. Synthesis by polymerase incorporation of nucleoside triphosphates and electrochemical properties
Symposium Series 2008, Vol. 10, pp. 178–181 [Abstract]
Published online 2015-10-30 18:37:09 - Nicolas Joubert, Jan Bárta, Milan Urban and Michal Hocek
Modular methodology for the syntheses of various aryl C-2'-deoxyribonucleosides
Symposium Series 2008, Vol. 10, pp. 173–177 [Abstract]
Published online 2015-10-30 18:37:03 - Petr Novák, Michal Hocek and Martin Kotora
New approaches to synthesis of C-deoxyribosides starting from C-alkynyldeoxyribosides
Symposium Series 2008, Vol. 10, pp. 168–172 [Abstract]
Published online 2015-10-30 18:36:57 - Michal Hocek, Peter Šilhár, Martin Kuchař, Zbyněk Hasník and Vítězslav Bambuch
Purine bases and nucleosides bearing functionalized C-substituents in position 6. Synthesis and biological activities
Symposium Series 2008, Vol. 10, pp. 164–167 [Abstract]
Published online 2015-10-30 18:36:52 - Zlatko Janeba, Antonín Holý and Zdeněk Zídek
Biological properties of the C-8 substituted analogues of 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA)
Symposium Series 2011, Vol. 12, pp. 344–346 [Abstract] - Tomáš Tichý, Graciela Andrei, Martin Dračínský, Antonín Holý, Jan Balzarini, Robert Snoeck and Marcela Krečmerová
New amphiphilic prodrugs of adefovir and cidofovir
Symposium Series 2011, Vol. 12, pp. 477–479 [Abstract]
Published online 2015-08-20 10:25:04 - Michal Tichý and Michal Hocek
Synthesis of 4-(het)aryl pyrimido[4,5-b]indole ribonucleosides
Symposium Series 2011, Vol. 12, pp. 475–476 [Abstract]
Published online 2015-08-20 10:24:59 - Petr Jansa, Petr Špaček, Antonín Holý, Ivan Votruba and Zlatko Janeba
Efficient one-pot synthesis of polysubstituted 6-[(1H-1,2,3-triazol-1-yl)methyl]uracils through the "click" protocol
Symposium Series 2011, Vol. 12, pp. 467–468 [Abstract]
Published online 2015-08-20 10:24:43 - Veronika Raindlová and Michal Hocek
Direct enzymatic synthesis of aldehyde-functionalized DNA and its conjugation with hydrazines and amines
Symposium Series 2011, Vol. 12, pp. 441–443 [Abstract]
Published online 2015-08-20 10:23:46 - Karel Pomeisl, Antonín Holý and Marcela Krečmerová
Use of 1,3-dioxolanes in the syntheses of α-branched alkyl and aryl N-9-[2-(phosphonomethoxy)ethyl]purines
Symposium Series 2011, Vol. 12, pp. 438–440 [Abstract]
Published online 2015-08-20 10:23:40 - Hana Pivoňková, Kateřina Němcová, Petra Horáková, Luděk Havran, Hana Macíčková-Cahová, Michal Hocek and Miroslav Fojta
Tail labelled oligonucleotide probes for the detection of DNA-protein interactions
Symposium Series 2011, Vol. 12, pp. 435–437 [Abstract]
Published online 2015-08-20 10:23:34 - Marcela Krečmerová, Antonín Holý, Dana Hocková, Martin Dračínský, Dianne T. Keough and Luke W. Guddat
9-[2-Hydroxy-3-(phosphonomethoxy)propyl] ("iso-HPMP") derivatives of purine bases and their side-chain modified analogues: synthesis and antimalarial activity
Symposium Series 2011, Vol. 12, pp. 381–382 [Abstract]
Published online 2015-08-20 10:19:45 - Pavel Kielkowski and Michal Hocek
Polymerase synthesis of modified DNA containing cytosine in major groove
Symposium Series 2011, Vol. 12, pp. 359–360 [Abstract]
Published online 2015-08-20 10:19:01 - Lubica Kalachova and Michal Hocek
Synthesis of nucleotides bearing oligopyridine ligands and their incorporation into DNA
Symposium Series 2011, Vol. 12, pp. 357–358 [Abstract]
Published online 2015-08-20 10:18:56 - Petr Jansa, Antonín Holý, Martin Dračínský, Ondřej Baszczyňski, Michal Česnek and Zlatko Janeba
The unique impact of microwave irradiaton on the chemistry of acyclic nucleoside phosphonates
Symposium Series 2011, Vol. 12, pp. 347–348 [Abstract]
Published online 2015-08-20 10:18:28 - Petr Jansa, Martin Maxmilian Kaiser, Antonín Holý and Zlatko Janeba
A novel, highly stereoselective synthetic approach for the preparation of substituted 2,5-dihydro-2,5-dihydroxyfurans
Symposium Series 2011, Vol. 12, pp. 339–341 [Abstract]
Published online 2015-08-20 10:13:05 - Martin Dračínský, Petr Jansa, Jana Chocholoušová, Jaroslav Vacek, Soňa Kovačková and Antonín Holý
The mechanism of isotopic exchange reaction of hydrogen H-5 of uracil derivatives in water and in non-protic solvents
Symposium Series 2011, Vol. 12, pp. 323–324 [Abstract]
Published online 2015-08-20 10:12:29 - Miroslava Čerňová and Michal Hocek
Dichotomy in regioselectivity of Pd-catalyzed direct C–H arylation of protected uracils
Symposium Series 2011, Vol. 12, pp. 314–316 [Abstract]
Published online 2015-08-20 10:12:11 - Lucie Čechová, Petr Jansa, Michal Šála, Martin Dračínský, Antonín Holý and Zlatko Janeba
The optimized microwave-assisted decomposition of formamides and its synthetic utility in the amination of purines and pyrimidines
Symposium Series 2011, Vol. 12, pp. 312–313 [Abstract]
Published online 2015-08-20 10:12:06 - Michal Česnek, Petra Břehová, Martin Dračínský, Antonín Holý and Zlatko Janeba
The efficient synthesis of 2-aryl substituted pyrimidine acyclic nucleoside phosphonates using Liebeskind-Srogl cross-coupling
Symposium Series 2011, Vol. 12, pp. 310–311 [Abstract]
Published online 2015-08-20 10:12:01 - Ondřej Baszczyňski, Petr Jansa, Dana Hocková, Zlatko Janeba, Martin Dračínský, Antonín Holý, Dianne T. Keough, John de Jersey and Luke W. Guddat
3-Fluoro-2-(phosphonomethoxy)propyl hypoxanthine and guanine derivatives as inhibitors of plasmodial hypoxanthine-guanine-xanthine phosphoribosyltransferases
Symposium Series 2011, Vol. 12, pp. 302–303 [Abstract]
Published online 2015-08-20 10:11:43 - Jan Bárta and Michal Hocek
Modular synthesis of 5-substituted thiophene and furan C-nucleosides and their analogues
Symposium Series 2011, Vol. 12, pp. 300–301 [Abstract]
Published online 2015-08-20 10:11:36 - Jana Balintová, Luděk Havran, Miroslav Fojta and Michal Hocek
Synthesis of nucleosides and nucleoside triphosphates bearing anthraquinone substituents as redox probes and their enzymatic incorporation to DNA
Symposium Series 2011, Vol. 12, pp. 297–299 [Abstract]
Published online 2015-08-20 10:11:31 - Jan Riedl and Michal Hocek
Synthesis of biaryl-substituted fluorescent nucleosides and nucleoside triphosphates and their incorporation to DNA
Symposium Series 2011, Vol. 12, pp. 233–235 [Abstract]
Published online 2015-08-20 10:02:23 - Pavla Perlíková, Petr Nauš, Aurelie Bourderioux and Michal Hocek
Hetaryl derivatives of 7-deazapurine ribonucleosides: potent cytostatic agents
Symposium Series 2011, Vol. 12, pp. 194–198 [Abstract]
Published online 2015-08-20 10:00:49 - Tomáš Kubelka, Martin Štefko, Jan Bárta, Nicolas Joubert, Milan Urban, Hubert Chapuis and Michal Hocek
Development of a general and modular approach to C-nucleosides
Symposium Series 2011, Vol. 12, pp. 180–183 [Abstract]
Published online 2015-08-20 10:00:32 - Dana Hocková, Antonín Holý, Michal Česnek, Ondřej Baszczyňski, Tomáš Tichý, Marcela Krečmerová, Zlatko Janeba, Tina S. Skinner-Adams, Lieve Naesens, Dianne T. Keoughd, John de Jersey and Luke W. Guddat
Acyclic nucleoside phosphonates as inhibitors of hypoxanthine-guanine-xanthine phosphoribosyltransferase: new anti-malarial chemotherapy leads
Symposium Series 2011, Vol. 12, pp. 171–174 [Abstract]
Published online 2015-08-20 10:00:19 - Miroslav Fojta, Luděk Havran, Petra Horáková, Hana Pivoňková, Pavel Kostečka, Hana Macíčková, Veronika Raindlová, Milan Vrabel and Michal Hocek
Redox labelling of nucleic acids for analyzing nucleotide sequences and monitoring DNA-protein interactions
Symposium Series 2011, Vol. 12, pp. 155–158 [Abstract]
Published online 2015-08-20 09:59:54 - Michal Hocek, Hana Macíčková-Cahová, Pavel Kielkowski, Veronika Raindlová, Lubica Kalachova, Jan Riedl, Jana Balintová and Petra Ménová
Polymerase construction of base-modified DNA for chemical biology
Symposium Series 2011, Vol. 12, pp. 152–154 [Abstract]
Published online 2015-08-20 09:59:48 - Zuzana Vaníková and Michal Hocek
Polymerase synthesis of new photocaged DNA
Symposium Series 2014, Vol. 14, pp. 392–393 [Abstract]
Published online 2015-07-06 23:09:39 - Michal Tichý and Michal Hocek
Synthesis and biological activity of thiophene fused 7-deazapurine ribonucleosides
Symposium Series 2014, Vol. 14, pp. 385–386 [Abstract]
Published online 2015-07-06 23:09:23 - Anna Simonova, Luděk Havran, Miroslav Fojta and Michal Hocek
New oxidative labels for electrochemical detection of DNA
Symposium Series 2014, Vol. 14, pp. 365–366 [Abstract]
Published online 2015-07-06 23:08:32 - Petr Orság, Hana Pivoňková, Jan Riedl, Michal Hocek and Miroslav Fojta
Utilisation of enzymatic labelling with 4-aminophtalimide and 4-hydroxybenzylideneimidazolinone fluorescent derivates for monitoring of DNA-protein interaction
Symposium Series 2014, Vol. 14, pp. 340–341 [Abstract]
Published online 2015-07-06 23:07:27 - Petra Ménová and Michal Hocek
Preparation of modified oligonucleotides by nicking enzyme amplification reaction
Symposium Series 2014, Vol. 14, pp. 324–325 [Abstract]
Published online 2015-07-06 23:06:55 - Michaela Mačková and Michal Hocek
Vinyl-modified DNA and its cleavage by restriction endonucleases
Symposium Series 2014, Vol. 14, pp. 318–319 [Abstract]
Published online 2015-07-06 23:06:39 - Pavel Kielkowski and Michal Hocek
Competitive incorporations of modified versus natural nucleotides by DNA polymerases
Symposium Series 2014, Vol. 14, pp. 295–296 [Abstract]
Published online 2015-07-06 23:05:36 - Miroslav Fojta, Aleš Daňhel, Petra Horáková, Medard Plucnara, Hana Pivoňková, Luděk Havran, Pavlína Vidláková, Veronika Raindlová, Jana Balintová, Hana Macíčková-Cahová and Michal Hocek
Electrochemical analysis of DNA using switchable redox moieties
Symposium Series 2014, Vol. 14, pp. 264–266 [Abstract]
Published online 2015-07-06 23:04:13 - Jitka Daďová, Petr Orság, Radek Pohl, Marie Brázdová, Miroslav Fojta and Michal Hocek
Study of DNA-protein interactions by cross-link formation using aqueous Michael addition
Symposium Series 2014, Vol. 14, pp. 240–241 [Abstract]
Published online 2015-07-06 23:03:09 - Jana Balintová, Marie Brázdová, Luděk Havran, Miroslav Fojta and Michal Hocek
Redox labeling and redox coding of nucleic acids
Symposium Series 2014, Vol. 14, pp. 229–230 [Abstract]
Published online 2015-07-06 23:02:33 - Jana Balintová, Jitka Daďová, Pavel Kielkowski, Petra Ménová, Zuzana Vaníková, Jan Riedl, Veronika Raindlová, Miroslav Fojta and Michal Hocek
Polymerase synthesis of base-modified DNA: new methods and new applications
Symposium Series 2014, Vol. 14, pp. 66–67 [Abstract]
Published online 2015-07-06 22:57:12 - Petr Nauš, Pavla Perlíková, Radek Pohl and Michal Hocek*
Sugar-modified derivatives of cytostatic 6-(het)aryl-7-deazapurine nucleosides: 2′-C-methylribonucleosides, arabinonucleosides and 2′-deoxy-2′-fluoroarabinonucleosides
2011, Vol. 76, Issue 8, pp. 957–988 [Abstract] - Ivan Votruba*, Jana Trýznová, Petra Břehová, Eva Tloušťová, Květoslava Horská, Jindřich Fanfrlík, Ondřej Přenosil and Antonín Holý
Inhibition of human purine nucleoside phosphorylase by tenofovir phosphate congeners
2010, Vol. 75, Issue 12, pp. 1249–1257 [Abstract] - Tomáš Elbert*, Petra Břehová and Antonín Holý
The preparation of 3H-labeled acyclic nucleoside phosphonates and study of their stability
2010, Vol. 75, Issue 7, pp. 757–766 [Abstract] - Zlatko Janeba*, Milena Masojídková and Antonín Holý
Alternative synthesis of 9-{3-[(diisopropoxyphosphoryl)methoxy]-2-hydroxypropyl}adenine and its free phosphonates substituted at the C-8 position of purine base
2010, Vol. 75, Issue 3, pp. 371–381 [Abstract] - Michal Šála, Hubert Hřebabecký*, Martin Dračínský, Milena Masojídková, Armando M. De Palma, Johan Neyts and Antonín Holý
Synthesis of novel racemic carbocyclic nucleosides derived from 5,6-disubstituted norbornene
2010, Vol. 75, Issue 1, pp. 1–20 [Abstract] - Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
New carbocyclic nucleoside analogues built on a bicyclo[2.2.2]octane-2,2-dimethanol template
2009, Vol. 74, Issue 9, pp. 1425–1441 [Abstract] - Zbyněk Hasník, Radek Pohl, Blanka Klepetářová and Michal Hocek*
Synthesis of (purin-6-yl)acetates and their transformations to 6-(2-hydroxyethyl)- and 6-(carbamoylmethyl)purines
2009, Vol. 74, Issue 7-8, pp. 1035–1059 [Abstract] [Full text pdf] - Hubert Hřebabecký*, Martin Dračínský, Armando M. De Palma, Johan Neyts and Antonín Holý
Synthesis of novel carbocyclic nucleoside analogues derived from 7-oxabicyclo[2.2.1]heptane-2-methanol
2009, Vol. 74, Issue 3, pp. 487–502 [Abstract] - Hubert Hřebabecký*, Martin Dračínský, Armando M. De Palma, Johan Neyts and Antonín Holý
Synthesis of novel racemic carbocyclic nucleoside analogues derived from 4,8-dioxatricyclo[4.2.1.03,7]nonane-9-methanol and 4-oxatricyclo[4.3.1.03,7]decane-10-methanol, compounds with activity against Coxsackie viruses
2009, Vol. 74, Issue 3, pp. 469–485 [Abstract] - Petr Nauš, Martin Kuchař and Michal Hocek*
Cytostatic and Antiviral 6-Arylpurine Ribonucleosides IX. Synthesis and Evaluation of 6-Substituted 3-Deazapurine Ribonucleosides
2008, Vol. 73, Issue 5, pp. 665–678 [Abstract] [Full text pdf] - Markéta Schinkmanová*, Ivan Votruba, Riri Shibata, Bin Han, Xiaohong Liu, Tomas Cihlar and Antonín Holý
Human N6-Methyl-AMP/DAMP Aminohydrolase (Abacavir 5'-Monophosphate Deaminase) is Capable of Metabolizing N6-Substituted Purine Acyclic Nucleoside Phosphonates
2008, Vol. 73, Issue 2, pp. 275–291 [Abstract] - Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
Synthesis of Novel Carbocyclic Nucleoside Analogues Containing Bicyclo[2.2.1]hept-2-ene-2-methanol
2008, Vol. 73, Issue 1, pp. 44–58 [Abstract] - Milan Dejmek, Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
Synthesis of Novel Carbocyclic Nucleoside Analogues Derived from 2-(Hydroxymethyl)bicyclo[2.2.1]heptane
2007, Vol. 72, Issue 11, pp. 1523–1544 [Abstract] - Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
Synthesis of Novel Carbocyclic Nucleosides and Pro-Tides Derived from 4-Oxatricyclo[4.2.1.03,7]nonane-9-methanol
2007, Vol. 72, Issue 10, pp. 1331–1349 [Abstract] - Silvie Vrbková*, Martin Dračínský and Antonín Holý
Bifunctional Acyclic Nucleoside Phosphonates: 2. Symmetrical 2-{[Bis(phosphono)methoxy]methyl}ethyl Derivatives of Purines and Pyrimidines
2007, Vol. 72, Issue 7, pp. 965–983 [Abstract] - Marcela Krečmerová*, Antonín Holý and Milena Masojídková
Pyrimidine Acyclic Nucleotide Analogues with Aromatic Substituents in C-5 Position
2007, Vol. 72, Issue 7, pp. 927–951 [Abstract] - Michal Hocek*, Peter Šilhár and Radek Pohl
Cytostatic and Antiviral 6-Arylpurine Ribonucleosides VIII. Synthesis and Evaluation of 6-Substituted Purine 3'-Deoxyribonucleosides
2006, Vol. 71, Issue 10, pp. 1484–1496 [Abstract] - Michal Česnek*, Milena Masojídková, Antonín Holý, Veronika Šolínová, Dušan Koval and Václav Kašička
Synthesis and Properties of 2-Guanidinopurines
2006, Vol. 71, Issue 9, pp. 1303–1319 [Abstract] - Michal Pechar*, Alena Braunová, Vladimír Šubr, Karel Ulbrich and Antonín Holý
Polymeric Conjugates of 9-[2-(Phosphonomethoxy)ethyl]purine with Potential Antiviral and Cytostatic Activity
2006, Vol. 71, Issue 8, pp. 1211–1220 [Abstract] - Hubert Hřebabecký*, Milena Masojídková, Martin Dračínský and Antonín Holý
Synthesis of Novel Conformationally Locked Carbocyclic Nucleosides Derived from 3-(Hydroxymethyl)bicyclo[2.2.1]heptane-2,5-diol
2006, Vol. 71, Issue 6, pp. 871–888 [Abstract] - Peter Šilhár, Radek Pohl, Ivan Votruba, Blanka Klepetářová and Michal Hocek*
Synthesis of 6-Amino-, 6-Methyl- and 6-Aryl-2-(hydroxymethyl)purine Bases and Nucleosides
2006, Vol. 71, Issue 6, pp. 788–803 [Abstract] - Michal Šála, Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
Synthesis of Novel Racemic Conformationally Locked Carbocyclic Nucleosides Derived from 7-Substituted Bicyclo[2.2.1]hept-5-ene-2,2-dimethanols
2006, Vol. 71, Issue 5, pp. 635–649 [Abstract] - Karel Pomeisl*, Ivan Votruba, Antonín Holý and Radek Pohl
Syntheses of Base and Side-Chain Modified Pyrimidine 1-[2-(Phosphonomethoxy)propyl] Derivatives as Potent Inhibitors of Thymidine Phosphorylase (PD-ECGF) from SD-Lymphoma
2006, Vol. 71, Issue 4, pp. 595–624 [Abstract] - Marcela Krečmerová*, Milena Masojídková and Antonín Holý
Preparation of C-5 Substituted Cidofovir Derivatives
2006, Vol. 71, Issue 4, pp. 579–594 [Abstract] - Silvie Vrbovská*, Antonín Holý, Radek Pohl and Milena Masojídková
Bifunctional Acyclic Nucleoside Phosphonates. 1. Symmetrical 1,3-Bis[(phosphonomethoxy)propan-2-yl] Derivatives of Purines and Pyrimidines
2006, Vol. 71, Issue 4, pp. 543–566 [Abstract] - Kateřina Hořejší, Radek Pohl and Antonín Holý*
Tricyclic Purine Analogs Derived from 2-Amino-6-chloropurine and 2,6-Diaminopurine and Their Methylated Quaternary Salts
2006, Vol. 71, Issue 1, pp. 77–90 [Abstract] - Květoslava Horská, Ivan Votruba* and Antonín Holý
Interaction of Phosphates of the Acyclic Nucleoside Phosphonates with Nucleoside Diphosphate Kinase from Yeast and Bovine Liver
2006, Vol. 71, Issue 1, pp. 35–43 [Abstract] - Šárka Chalupová*, Antonín Holý and Milena Masojídková
Synthesis of N4-Substituted Derivatives of 1-[2-(Phosphonomethoxy)ethyl]cytosine and Its Diisopropyl Ester as a Model Reaction for the Synthesis of N4-Substituted Derivatives of Cidofovir
2005, Vol. 70, Issue 12, pp. 2066–2074 [Abstract] - Šárka Chalupová*, Antonín Holý and Milena Masojídková
Synthesis of Some N4-Substituted Derivatives of 1-[(S)-3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine (HPMPC, Cidofovir)
2005, Vol. 70, Issue 12, pp. 2053–2065 [Abstract] - Peter Šilhár, Radek Pohl, Ivan Votruba and Michal Hocek*
Synthesis of 2-Substituted 6-(Hydroxymethyl)purine Bases and Nucleosides
2005, Vol. 70, Issue 10, pp. 1669–1695 [Abstract] - Karel Pomeisl*, Radek Pohl, Antonín Holý and Ivan Votruba
Simple Transformation of Thymine 1-[3-Hydroxy-2-(phosphonomethoxy)propyl] Derivatives to Their 1-[3-Fluoro-2-(phosphonomethoxy)propyl] Counterparts
2005, Vol. 70, Issue 9, pp. 1465–1481 [Abstract] - Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
Synthesis of Novel Conformationally Locked Carbocyclic Nucleosides Derived from 5,5- and 6,6-Bis(hydroxymethyl)bicyclo[2.2.1]heptan-2-ol
2005, Vol. 70, Issue 4, pp. 519–538 [Abstract] - Pavel Turek, Martin Kotora*, Michal Hocek* and Ivan Votruba
Novel Method for Preparation of Highly Substituted 6-Arylpurines by Reactions of 6-Alkynylpurines with Zirconacyclopentadienes
2005, Vol. 70, Issue 3, pp. 339–349 [Abstract] - Dana Hocková*, Milena Masojídková and Antonín Holý
Sonogashira Cross-Coupling in the Synthesis of Acyclic Nucleoside Phosphonates: Preparation of 6-[(Phosphonomethoxy)alkynyl]- and 6-[(Phosphonomethoxy)alkyl]pyrimidines
2005, Vol. 70, Issue 2, pp. 247–258 [Abstract] - Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
Synthesis of Racemic 9-(6- and 2,6-Substituted 9H-Purin-9-yl)-5-oxatricyclo[4.2.1.03,7]nonane-3-methanols, Novel Conformationally Locked Carbocyclic Nucleosides
2005, Vol. 70, Issue 1, pp. 103–123 [Abstract] - Petr Nauš, Ivan Votruba and Michal Hocek*
Covalent Analogues of DNA Base-Pairs and Triplets VII. Synthesis and Cytostatic Activity of Bis(purin-6-yl)acetylene and -diacetylene Nucleosides
2004, Vol. 69, Issue 10, pp. 1955–1970 [Abstract] - Marcela Krečmerová*, Milena Masojídková and Antonín Holý
Synthesis of N9- and N7-[2-Hydroxy-3-(phosphonomethoxy)propyl] Derivatives of N6-Substituted Adenines, 2,6-Diaminopurines and Related Compounds
2004, Vol. 69, Issue 10, pp. 1889–1913 [Abstract] - Michal Šála, Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
Synthesis of Racemic 2-Hydroxy-4- and 2-Hydroxy-5-(hydroxymethyl)cyclohexane Pyrimidine C-Nucleoside Analogues
2004, Vol. 69, Issue 4, pp. 918–932 [Abstract] - Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
Synthesis of Purine Nucleoside Analogues Derived from Carbocyclic 5-C-(Hydroxymethyl)hexopyranoses
2004, Vol. 69, Issue 2, pp. 435–452 [Abstract] - Michal Česnek*, Antonín Holý and Milena Masojídková
New 2-Alkynyl Derivatives of the Acyclic Nucleoside 9-(2,3-Dihydroxypropyl)adenine and Their 6-Guanidinopurine Counterparts as Potential Effectors of Adenosine Receptors
2003, Vol. 68, Issue 11, pp. 2201–2218 [Abstract] - Marcela Krečmerová*, Miloš Buděšínský, Milena Masojídková and Antonín Holý
Synthesis of Optically Active N6-Alkyl Derivatives of (R)-3-(Adenin-9-yl)-2-hydroxypropanoic Acid and Related Compounds
2003, Vol. 68, Issue 5, pp. 931–950 [Abstract] - Michal Hocek*, Dana Hocková and Jan Štambaský
Cytostatic 6-Arylpurine Nucleosides V. Synthesis of 8-Substituted 6-Phenylpurine Ribonucleosides
2003, Vol. 68, Issue 5, pp. 837–848 [Abstract] - Petr Čapek, Miroslav Otmar*, Milena Masojídková, Ivan Votruba and Antonín Holý
A Facile Synthesis of 9-Deaza Analogue of Olomoucine
2003, Vol. 68, Issue 4, pp. 779–791 [Abstract] - Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
Synthesis of Racemic 2-Hydroxy-4- and 2-Hydroxy-5-(hydroxymethyl)cyclohexane Nucleoside Analogues
2002, Vol. 67, Issue 11, pp. 1681–1699 [Abstract] - Michal Hocek*, Hana Dvořáková and Ivana Císařová
Covalent Analogues of DNA Base-Pairs and Triplets V. Synthesis of Purine-Purine and Purine-Pyrimidine Conjugates Connected by Diverse Types of Acyclic Carbon Linkages
2002, Vol. 67, Issue 10, pp. 1560–1578 [Abstract] - Michal Hocek*, Irena G. Stará, Ivo Starý and Hana Dvořáková
Covalent Analogues of DNA Base-Pairs and Triplets IV. Synthesis of Trisubstituted Benzenes Bearing Purine and/or Pyrimidine Rings by Cyclotrimerization of 6-Ethynylpurines and/or 5-Ethynyl-1,3-dimethyluracil
2002, Vol. 67, Issue 8, pp. 1223–1235 [Abstract] - Michal Hocek*, Antonín Holý and Hana Dvořáková
Cytostatic 6-Arylpurine Nucleosides IV. Synthesis of 2-Substituted 6-Phenylpurine Ribonucleosides
2002, Vol. 67, Issue 3, pp. 325–335 [Abstract] - Gabriel Birkuš, Ivan Votruba*, Miroslav Otmar and Antonín Holý
Interactions of 1-[(S)-3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine (Cidofovir) Diphosphate with DNA Polymerases α, δ and ε*
2001, Vol. 66, Issue 11, pp. 1698–1706 [Abstract] - Antonín Holý*, Ivan Votruba, Eva Tloušťová and Milena Masojídková
Synthesis and Cytostatic Activity of N-[2-(Phosphonomethoxy)alkyl] Derivatives of N6-Substituted Adenines, 2,6-Diaminopurines and Related Compounds
2001, Vol. 66, Issue 10, pp. 1545–1592 [Abstract] - Zlatko Janeba*, Antonín Holý and Milena Masojídková
Transformation of 8-[(2-Hydroxyalkyl)sulfanyl]adenines to 6-Amino-7H-purin-8(9H)-one Derivatives
2001, Vol. 66, Issue 9, pp. 1393–1406 [Abstract] - Hubert Hřebabecký* and Antonín Holý
Synthesis of Carba Analogues of Deoxy-4-C-(hydroxymethyl)hexopyranoses, Intermediates in the Synthesis of Carbocyclic Nucleosides
2001, Vol. 66, Issue 5, pp. 785–798 [Abstract] - Zlatko Janeba*, Antonín Holý and Milena Masojídková
Synthesis of 8-Amino- and N-Substituted 8-Aminoadenine Derivatives of Acyclic Nucleoside and Nucleotide Analogs
2001, Vol. 66, Issue 3, pp. 517–532 [Abstract] - Miroslav Otmar*, Lucie Poláková, Milena Masojídková and Antonín Holý
A Facile Synthesis of Azetidin-2-ylphosphonic Acid and Its 1-Alkyl Derivatives
2001, Vol. 66, Issue 3, pp. 507–516 [Abstract] - Miroslav Otmar*, Milena Masojídková, Ivan Votruba and Antonín Holý
An Alternative Synthesis of HPMPC and HPMPA Diphosphoryl Derivatives
2001, Vol. 66, Issue 3, pp. 500–506 [Abstract] - Michal Hocek*, Antonín Holý, Ivan Votruba and Hana Dvořáková
Cytostatic 6-Arylpurine Nucleosides III. Synthesis and Structure-Activity Relationship Study in Cytostatic Activity of 6-Aryl-, 6-Hetaryl- and 6-Benzylpurine Ribonucleosides
2001, Vol. 66, Issue 3, pp. 483–499 [Abstract] - Petr Alexander*, Antonín Holý, Miloš Buděšínský and Milena Masojídková
Synthesis of Acyclic Nucleotide Analogues Derived from N3-Substituted Isoguanine
2000, Vol. 65, Issue 11, pp. 1713–1725 [Abstract] - Zlatko Janeba*, Antonín Holý and Milena Masojídková
Synthesis of Acyclic Nucleoside and Nucleotide Analogs Derived from 6-Amino-7H-purine-8(9H)-thione and 8-(Methylsulfanyl)adenine
2000, Vol. 65, Issue 11, pp. 1698–1712 [Abstract] - Michal Hocek*, Antonín Holý, Ivan Votruba and Hana Dvořáková
Cytostatic 6-Arylpurine Nucleosides II. Synthesis of Sugar-Modified Derivatives: 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-, 9-(5-Deoxy-β-D-ribofuranosyl)- and 9-(2,3-Dihydroxypropyl)-6-phenylpurines
2000, Vol. 65, Issue 11, pp. 1683–1697 [Abstract] - Romana Krejčová, Květoslava Horská, Ivan Votruba* and Antonín Holý
Phosphorylation of Purine (Phosphonomethoxy)alkyl Derivatives by Mitochondrial AMP Kinase (AK2 Type) from L1210 Cells
2000, Vol. 65, Issue 10, pp. 1653–1668 [Abstract] - Michal Česnek, Michal Hocek* and Antonín Holý
Synthesis of Acyclic Nucleotide Analogues Derived from 2-Amino-6-C-substituted Purines via Cross-Coupling Reactions of 2-Amino-9-{2-[(diisopropoxyphosphoryl)methoxy]ethyl}-6-halopurines with Diverse Organometallic Reagents
2000, Vol. 65, Issue 8, pp. 1357–1373 [Abstract] - Zlatko Janeba*, Antonín Holý and Milena Masojídková
Synthesis of Acyclic Nucleoside and Nucleotide Analogs Derived from 6-Amino-7H-purin-8(9H)-one
2000, Vol. 65, Issue 7, pp. 1126–1144 [Abstract] - Kateřina Meszárosová, Antonín Holý* and Milena Masojídková
Synthesis of Acyclic Adenine 8,N-Anhydronucleosides
2000, Vol. 65, Issue 7, pp. 1109–1125 [Abstract] - Hubert Hřebabecký* and Antonín Holý
Synthesis of Carbocyclic 4'-C-Hydroxymethyl Analogues of Azidodeoxythymidine, Deoxythymidine, Deoxydidehydrothymidine and Thymidine Carba Analogue with Fused Oxetane Ring
2000, Vol. 65, Issue 3, pp. 395–406 [Abstract] - Hubert Hřebabecký* and Antonín Holý
Synthesis of Carba Analogues of 2'-Deoxy-4'-C-(hydroxymethyl)nucleosides
1999, Vol. 64, Issue 9, pp. 1485–1496 [Abstract] - Dana Hocková*, Milena Masojídková and Antonín Holý
7-(1-Cyanobut-3-en-1-yl)-N6-[(N,N-dimethylamino)methylene]adenine as a Starting Compound for the Synthesis of α-Branched Acyclic Analogues of N7-Isomer of Adenosine
1999, Vol. 64, Issue 8, pp. 1316–1324 [Abstract] - Claudia A. Blindauer, Antonín Holý and Helmut Sigel*
Metal Ion-Binding Properties of the Nucleotide Analogue 1-[2-(Phosphonomethoxy)ethyl]cytosine (PMEC) in Aqueous Solution
1999, Vol. 64, Issue 4, pp. 613–632 [Abstract] - Romana Krejčová, Květoslava Horská, Ivan Votruba* and Antonín Holý
Isoenzymes of GMP Kinase from L1210 Cells: Isolation and Characterization
1999, Vol. 64, Issue 3, pp. 559–570 [Abstract] - Antonín Holý*, Miloš Buděšínský, Jaroslav Podlaha and Ivana Císařová
Synthesis of Quaternary 1-[2-(Phosphonomethoxy)ethyl] Derivatives of 2,4-Diaminopyrimidine and Related Acyclic Nucleotide Analogs
1999, Vol. 64, Issue 2, pp. 242–256 [Abstract] - Michal Hocek* and Antonín Holý
Perfluoroalkylation of 6-Iodopurines by Trimethyl(perfluoroalkyl)silanes. Synthesis of 6-(Perfluoroalkyl)purine Bases, Nucleosides and Acyclic Nucleotide Analogues
1999, Vol. 64, Issue 2, pp. 229–241 [Abstract] - Hana Dvořáková, Dalimil Dvořák and Antonín Holý
Synthesis of Acyclic Nucleotide Analogues Derived from 6-(sec- or tert-Alkyl)purines via Coupling of 6-Chloropurine Derivatives with Organocuprates
1998, Vol. 63, Issue 12, pp. 2065–2074 [Abstract] - Hubert Hřebabecký, Milena Masojídková and Antonín Holý
Synthesis of Carba Analogues of Deoxy-4-C-(hydroxymethyl)pentofuranoses, Intermediates in the Synthesis of Carbocyclic Nucleosides
1998, Vol. 63, Issue 12, pp. 2044–2064 [Abstract] - Gabriel Birkuš, Pavel Kramata, Ivan Votruba, Berta Otová, Miroslav Otmar and Antonín Holý
Nonproteolyzed Form of DNA-Polymerase ε from T-Cell Spontaneous Lymphoma of Sprague-Dawley Inbred Rat: Isolation and Characterization
1998, Vol. 63, Issue 5, pp. 723–731 [Abstract] - Hubert Hřebabecký and Antonín Holý
Preparation of Thymidine-4'-C-carboxylic Acid and Its Derivatives
1997, Vol. 62, Issue 7, pp. 1128–1135 [Abstract] - Hubert Hřebabecký, Jan Balzarini and Antonín Holý
Preparation of Chloro and Sulfanyl Derivatives of 1-(2-Deoxy-4-C-hydroxymethyl-α-L-threo-Pentofuranosyl)uracil
1997, Vol. 62, Issue 7, pp. 1114–1127 [Abstract] - Hubert Hřebabecký, Miloš Buděšínský, Milena Masojídková, Zdeněk Havlas and Antonín Holý
1-(3,5-O-Alkylidene-2-deoxy-4-C-hydroxymethyl-α-L-threo-pentofuranosyl)uracils
1997, Vol. 62, Issue 6, pp. 957–970 [Abstract] - Dana Hocková and Antonín Holý
Synthesis of Some "Abbreviated" NAD+ Analogues
1997, Vol. 62, Issue 6, pp. 948–956 [Abstract] - Lenka Olšanská, Tomas Cihlar, Ivan Votruba* and Antonín Holý
Transport of Adefovir (PMEA) in Human T-Lymphoblastoid Cells
1997, Vol. 62, Issue 5, pp. 821–828 [Abstract] - Michal Hocek, Milena Masojídková and Antonín Holý
Synthesis of Acyclic Nucleotide Analogues Derived from 6-Hetarylpurines via Cross-Coupling Reactions of 9-[2-(Diethoxyphosphonylmethoxy)ethyl]-6-iodopurine with Hetaryl Organometallic Reagents
1997, Vol. 62, Issue 1, pp. 136–146 [Abstract] - Jaroslav Zajíček, Ivan Rosenberg, Radek Liboska, Zdeněk Točík, G. Victor Fazakerley, Wilhelm Guschlbauer and Antonín Holý
Conformational Studies on Diribonucleoside Monophosphate Analogs Containing a Nonisosteric, Isopolar, Phosphonate-Based Internucleotide Linkage
1997, Vol. 62, Issue 1, pp. 83–98 [Abstract] - Pavel Kramata, Gabriel Birkuš, Miroslav Otmar, Ivan Votruba and Antonín Holý
Structural features of acyclic nucleotide analogs conferring inhibitory effects on cellular replicative DNA polymerases
1996, Vol. 61, Special Issue, pp. S188–S191 [Abstract] - Antonín Holý, Zdeněk Zídek and Ivan Votruba
Inhibition of murine lymphocyte proliferation by N6-substituted acyclic purine nucleoside phosphonates
1996, Vol. 61, Special Issue, pp. S182–S187 [Abstract] - Romana Krejčová, Květoslava Horská, Ivan Votruba and Antonín Holý
Phosphorylation of phosphonomethoxyalkylguanines by GMP-kinase isoenzymes
1996, Vol. 61, Special Issue, pp. S134–S136 [Abstract] - Lan Dinh Chu, Hubert Hřebabecký and Antonín Holý
A new synthesis of 2,2'-anhydro-5-alkyl/aryl-3-glycosyluracils
1996, Vol. 61, Special Issue, pp. S129–S131 [Abstract] - Roman Wágner, Dalimil Dvořák and Antonín Holý
New application of the Stille coupling in the synthesis of 5-substituted uracils
1996, Vol. 61, Special Issue, pp. S118–S119 [Abstract] - Zlatko Janeba and Antonín Holý
Intramolecular cyclization of some (S)-9-(3-hydroxy-2-phosphonomethoxypropyl)adenine derivatives
1996, Vol. 61, Special Issue, pp. S116–S117 [Abstract] - Michal Hocek and Antonín Holý
Acyclic nucleotide analogues derived from 6-(1-aminoalkyl)purines
1996, Vol. 61, Special Issue, pp. S55–S58 [Abstract] - Dana Hocková and Antonín Holý
"Abbreviated" NAD+ analogues containing a phosphonate function
1996, Vol. 61, Special Issue, pp. S52–S54 [Abstract] - Miroslav Otmar, Milena Masojídková and Antonín Holý
Two synthetic approaches to 9-deaza analogues of 9-(2,3-dihydroxypropyl)adenine (DHPA)
1996, Vol. 61, Special Issue, pp. S49–S51 [Abstract] - Dana Hocková, Milena Masojídková and Antonín Holý
"Abbreviated" NAD+ Analogues Containinga Phosphonate Function
1996, Vol. 61, Issue 10, pp. 1538–1548 [Abstract] - Michal Hocek, Milena Masojídková, Antonín Holý, Graciela Andrei, Robert Snoeck, Jan Balzarini and Erik De Clercq
Synthesis and Antiviral Activity of Acyclic Nucleotide Analogues Derived from 6-(Aminomethyl)purines and Purine-6-carboxamidines
1996, Vol. 61, Issue 10, pp. 1525–1537 [Abstract] - Marcela Krečmerová, Hubert Hřebabecký and Antonín Holý
Synthesis of 5-Phenylcytosine Nucleoside Derivatives
1996, Vol. 61, Issue 4, pp. 645–655 [Abstract] - Marcela Krečmerová, Hubert Hřebabecký and Antonín Holý
Preparation of 5-Benzyluracil and 5-Benzylcytosine Nucleosides as Potential Inhibitors of Uridine Phosphorylase
1996, Vol. 61, Issue 4, pp. 627–644 [Abstract] - Marcela Krečmerová, Hubert Hřebabecký, Milena Masojídková and Antonín Holý
2',3'-Dideoxy- and 3'-Azido-2',3'-dideoxynucleosides of 5-Phenyl-2(1H)-pyrimidinone. Preparation of 2',3'-Dideoxypentofuranoses
1996, Vol. 61, Issue 3, pp. 478–488 [Abstract] - Marcela Krečmerová, Hubert Hřebabecký, Milena Masojídková and Antonín Holý
Synthesis of 5-Phenyl-2(1H)-pyrimidinone Nucleosides
1996, Vol. 61, Issue 3, pp. 458–477 [Abstract] - Zlatko Janeba, Antonín Holý, Hana Votavová and Milena Masojídková
Intramolecular Cyclization of Some Acyclic Nucleoside Analogs
1996, Vol. 61, Issue 3, pp. 442–457 [Abstract] - Pavel Kramata, Jaroslav Černý, Gabriel Birkuš, Ivan Votruba, Berta Otová and Antonín Holý
DNA-Polymerases α, δ and ε from T-Cell Spontaneous Lymphoblastic Leukemia of Sprague-Dawley Inbred Rat: Isolation and Characterization
1995, Vol. 60, Issue 9, pp. 1555–1572 [Abstract] - Antonín Holý, Hana Dvořáková and Milena Masojídková
Synthesis of Enantiomeric N-(2-Phosphonomethoxypropyl) Derivatives of Purine and Pyrimidine Bases. II. The Synthon Approach
1995, Vol. 60, Issue 8, pp. 1390–1409 [Abstract] - Antonín Holý and Milena Masojídková
Synthesis of Enantiomeric N-(2-Phosphonomethoxypropyl) Derivatives of Purine and Pyrimidine Bases. I. The Stepwise Approach
1995, Vol. 60, Issue 7, pp. 1196–1212 [Abstract] - Michal Hocek, Milena Masojídková and Antonín Holý
Synthesis of Acyclic Nucleotide Analogues Derived from 2-(Aminomethyl)adenine and 2-(Aminomethyl)hypoxanthine
1995, Vol. 60, Issue 5, pp. 875–882 [Abstract] - Marcela Krečmerová, Antonín Holý and Milena Masojídková
Synthesis of 3-(4-Pyridinyl)-, 3-(2-Chloro-4-pyridinyl)- and 3-(2-Amino-4-pyridinyl)propoxymethanephosphonic Acid
1995, Vol. 60, Issue 4, pp. 670–680 [Abstract] - Marcela Krečmerová and Antonín Holý
Preparation of Phosphonomethyl Ethers Derived from 2-Phenylethanol and Its Amino Derivatives
1995, Vol. 60, Issue 4, pp. 659–669 [Abstract] - Kristina Juricová, Svatava Smrčková and Antonín Holý
Synthesis of Base-Modified "Abbreviated" NAD Analogues
1995, Vol. 60, Issue 2, pp. 237–250 [Abstract] - Dana Hocková, Milena Masojídková, Miloš Buděšínský and Antonín Holý
Acyclic Nucleoside and Nucleotide Analogs Derived from 2-Azaadenine
1995, Vol. 60, Issue 2, pp. 224–236 [Abstract] - Ivan Votruba, Antonín Holý, Hana Dvořáková, Jaroslav Günter, Dana Hocková, Hubert Hřebabecký, Tomas Cihlar and Milena Masojídková
Synthesis of 2-Deoxy-β-D-ribonucleosides and 2,3-Dideoxy-β-D-pentofuranosides on Immobilized Bacterial Cells
1994, Vol. 59, Issue 10, pp. 2303–2330 [Abstract] - Petr Alexander and Antonín Holý
Prodrugs of Analogs of Nucleic Acid Components
1994, Vol. 59, Issue 10, pp. 2127–2165 [Abstract] - Hana Dvořáková, Antonín Holý and Ivan Rosenberg
Synthesis of Some 2'-C-Alkyl Derivatives of 9-(2-Phosphonomethoxyethyl)adenine and Related Compounds
1994, Vol. 59, Issue 9, pp. 2069–2094 [Abstract] - Petr Alexander, Antonín Holý and Milena Masojídková
Synthesis of 9-(2-Phosphinomethoxyethyl)adenine and Related Compounds
1994, Vol. 59, Issue 8, pp. 1870–1878 [Abstract] - Petr Alexander, Antonín Holý and Milena Masojídková
Preparation of 9-(2-Phosphonomethoxyethyl)adenine Esters as Potential Prodrugs
1994, Vol. 59, Issue 8, pp. 1853–1869 [Abstract] - Hubert Hřebabecký and Antonín Holý
Synthesis of Deoxy, Dideoxy and Didehydrodideoxy Analogs of 9-(4-C-Hydroxymethyl-α-L-pentofuranosyl)adenine
1994, Vol. 59, Issue 7, pp. 1654–1664 [Abstract] - Hubert Hřebabecký, Jan Dočkal and Antonín Holý
Synthesis of Deoxy, Dideoxy and Didehydrodideoxy Analogs of 9-(β-D-Hexofuranosyl)adenine
1994, Vol. 59, Issue 6, pp. 1408–1419 [Abstract] - Maria Spassova, Hana Dvořáková, Antonín Holý, Miloš Buděšínský and Milena Masojídková
Synthesis of N-(3-Azido-2-hydroxypropyl), N-(3-Phthalimido-2-hydroxypropyl) and N-(3-Amino-2-hydroxypropyl) Derivatives of Heterocyclic Bases
1994, Vol. 59, Issue 5, pp. 1153–1174 [Abstract] - Stanislav Böhm, Michal Hocek, Jan Němeček, Vladimír Havlíček and Josef Kuthan
Preparation and Spectroscopic Properties of Spirocyclic 1-Methyl-2,4,4,6-tetraaryl-1,4-dihydropyridines
1994, Vol. 59, Issue 5, pp. 1105–1114 [Abstract] - Hubert Hřebabecký and Antonín Holý
Synthesis of 1-(3-Azido-2,3-dideoxy-β-D-ribo-hexofuranosyl)-, 1-(2,3-Dideoxy-β-D-erythro-hexofuranosyl)- and 1-(2,3-Dideoxy-β-D-erythro-hex-2-enofuranosyl)pyrimidine Nucleosides
1994, Vol. 59, Issue 2, pp. 412–420 [Abstract] - Stanislav Böhm, Michal Hocek, Stanislav Nešpůrek and Josef Kuthan
Photocolouration of 2,4,4,6-Tetraaryl-1,4-dihydropyridines: A Semiempirical Quantum Chemical Study
1994, Vol. 59, Issue 2, pp. 262–272 [Abstract] - Miroslav Otmar, Ivan Rosenberg, Milena Masojídková and Antonín Holý
[5-(9-Adeninyl)-5'-deoxy-L-pentofuranosyl]phosphonates: Conformationally restricted nucleotide analogs related to (S)-HPMPA
1993, Vol. 58, Special Issue, pp. S256–S258 [Abstract] - Hubert Hřebabecký, Jan Dočkal and Antonín Holý
Synthesis of deoxy, dideoxy and didehydrodideoxy analogues of 9-(β-D-hexofuranosyl)adenine and 9-(4-C-hydroxymethyl-α-L-pentofuranosyl)adenine
1993, Vol. 58, Special Issue, pp. S241–S243 [Abstract] - Antonín Holý, Hana Dvořáková and Ivan Rosenberg
Synthesis and antiviral activity of some 2'-C-alkyl derivatives of 9-(2-phosphonomethoxyethyl)adenine
1993, Vol. 58, Special Issue, pp. S86–S90 [Abstract] - Miroslav Otmar, Ivan Rosenberg, Milena Masojídková and Antonín Holý
[5-(Adenin-9-yl)-5-deoxy-L-pentofuranosyl]phosphonates - A Novel Type of Nucleotide Analogs Related to HPMPA. II. Synthesis of L-ribo and L-xylo Configurated Derivatives by Recyclization of Diethyl (5-RS)-[1,2-O-Isopropylidene-5-O-methanesulfonyl-D-pentofuranos-5-C-yl]phosphonates under Acidic Conditions
1993, Vol. 58, Issue 9, pp. 2180–2196 [Abstract] - Miroslav Otmar, Ivan Rosenberg, Milena Masojídková and Antonín Holý
[5-(Adenin-9-yl)-5-deoxypentofuranosyl]phosphonates - A Novel Type of Nucleotide Analogs Related to HPMPA. I. Derivatives with L-arabino, D-arabino, 2-Deoxy-L-erythro and 2-Deoxy-L-threo Configuration
1993, Vol. 58, Issue 9, pp. 2159–2179 [Abstract] - Hubert Hřebabecký and Antonín Holý
Synthesis of 1-(2,3-Dideoxy-4-C-methyl-β-D-glycero-pent-2-enofuranosyl)thymine, 1-(2,3-Dideoxy-4-C-methyl-β-D-glycero-pentofuranosyl)thymine and 1-(4-C-Azidomethyl-2-deoxy-β-D-threo-pentofuranosyl)thymine
1993, Vol. 58, Issue 7, pp. 1668–1674 [Abstract] - Jindřich Jindřich, Antonín Holý and Hana Dvořáková
Synthesis of N-(3-Fluoro-2-phosphonomethoxypropyl) (FPMP) Derivatives of Heterocyclic Bases
1993, Vol. 58, Issue 7, pp. 1645–1667 [Abstract] - Hana Dvořáková and Antonín Holý
Synthesis and Biological Effects of N-(2-Phosphonomethoxyethyl) Derivatives of Deazapurine Bases
1993, Vol. 58, Issue 6, pp. 1419–1429 [Abstract] - Hana Dvořáková, Antonín Holý and Petr Alexander
Synthesis and Biological Effects of 9-(3-Hydroxy-2-phosphonomethoxypropyl) Derivatives of Deazapurine Bases
1993, Vol. 58, Issue 6, pp. 1403–1418 [Abstract] - Petr Alexander and Antonín Holý
General Method of Preparation of N-[(S)-(3-Hydroxy-2-phosphonomethoxypropyl)] Derivatives of Heterocyclic Bases
1993, Vol. 58, Issue 5, pp. 1151–1163 [Abstract] - Antonín Holý
Syntheses of Enantiomeric N-(3-Hydroxy-2-phosphonomethoxypropyl) Derivatives of Purine and Pyrimidine Bases
1993, Vol. 58, Issue 3, pp. 649–674 [Abstract] - Hana Dvořáková, Antonín Holý, Ivan Votruba and Milena Masojídková
Synthesis and Biological Effects of Acyclic Analogs of Deazapurine Nucleosides
1993, Vol. 58, Issue 3, pp. 629–648 [Abstract] - Marcela Krečmerová, Hubert Hřebabecký, Milena Masojídková and Antonín Holý
Preparation of Purine 2'-Deoxy-5'-O-phosphonomethylnucleosides and 2'-Deoxy-3'-O-phosphonomethylnucleosides
1993, Vol. 58, Issue 2, pp. 421–434 [Abstract] - Hubert Hřebabecký and Antonín Holý
Synthesis of 1-(3-Azido-2,3-dideoxy-4-C-hydroxymethyl-α-L-threo-pentofuranosyl)thymine, 1-(2,3-Dideoxy-4-C-hydroxymethyl-α-L-glycero-pentofuranosyl)thymine and 1-(2,3-Dideoxy-4-C-hydroxymethyl-α-L-glycero-pent-2-enofuranosyl)thymine
1993, Vol. 58, Issue 2, pp. 409–420 [Abstract] - Jindřich Jindřich, Hana Dvořáková and Antonín Holý
Synthesis of Isomeric N-(3-Fluoro-2-hydroxypropyl) and N-(2-Fluoro-3-hydroxypropyl) Derivatives of Purine and Pyrimidine Bases
1992, Vol. 57, Issue 7, pp. 1466–1482 [Abstract] - Tomas Cihlar, Ivan Votruba, Květoslava Horská, Radek Liboska, Ivan Rosenberg and Antonín Holý
Metabolism of 1-(S)-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine (HPMPC) in Human Embryonic Lung Cells
1992, Vol. 57, Issue 3, pp. 661–672 [Abstract] - Marcela Krečmerová, Hubert Hřebabecký and Antonín Holý
5'-O-Phosphonylmethyl derivatives of 2'-deoxynucleosides
1990, Vol. 55, Special Issue, pp. S121–S124 [Abstract] - Katarina Šedivá, Ivan Votruba, Antonín Holý and Ivan Rosenberg
Purine nucleoside phosphorylase: Isolation and characterization
1990, Vol. 55, Issue 12, pp. 2987–2999 [Abstract] - Marcela Krečmerová, Hubert Hřebabecký and Antonín Holý
Synthesis of 5'-O-phosphonomethyl derivatives of pyrimidine 2'-deoxynucleosides
1990, Vol. 55, Issue 10, pp. 2521–2536 [Abstract] - Květa Horská, Aleš Cvekl, Ivan Rosenberg, Antonín Holý and Karel Šebesta
DNA-dependent RNA polymerase mediated formation of methylphosphonyl internucleotide linkage
1990, Vol. 55, Issue 8, pp. 2100–2109 [Abstract] - Hubert Hřebabecký, Antonín Holý and Eric De Clercq
Synthesis of 3'-azido-2',3'-dideoxy-6-methyluridine, 2',3'-dideoxy-6-methyluridine and 2',3'-dideoxy-2',3'-didehydro-6-methyluridine
1990, Vol. 55, Issue 7, pp. 1801–1811 [Abstract] - Antonín Holý, Ivan Rosenberg and Hana Dvořáková
Synthesis of N-(2-(2-phosphonylethoxy)ethyl) derivatives of heterocyclic bases
1990, Vol. 55, Issue 3, pp. 809–818 [Abstract] - Marcela Krečmerová, Miloslav Černý, Miloš Buděšínský and Antonín Holý
Utilization of 1,6-anhydrohexoses for the preparation of some aliphatic adenosine analogs
1989, Vol. 54, Issue 10, pp. 2753–2766 [Abstract] - Antonín Holý, Ivan Rosenberg and Hana Dvořáková
Synthesis of (3-hydroxy-2-phosphonylmethoxypropyl) derivatives of heterocyclic bases
1989, Vol. 54, Issue 9, pp. 2470–2501 [Abstract] - Antonín Holý, Ivan Rosenberg and Hana Dvořáková
Synthesis of N-(2-phosphonylmethoxyethyl) derivatives of heterocyclic bases
1989, Vol. 54, Issue 8, pp. 2190–2210 [Abstract] - Aleš Cvekl, Květa Horská, Karel Šebesta, Ivan Rosenberg and Antonín Holý
Trinucleotide AUA and UAU formation catalyzed by wheat germ RNA polymerase II
1989, Vol. 54, Issue 3, pp. 811–818 [Abstract] - Antonín Holý
Synthesis of 3-amino- and 3-azidoanalogs of 9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine (HPMPA)
1989, Vol. 54, Issue 2, pp. 446–454 [Abstract] - Antonín Holý
Branched-chain derivatives of acyclic adenosine analogs: Alkyl and hydroxymethyl derivatives of S-adenosyl-L-homocysteinase inhibitors substituted at the 2- and 3-position of the side chain
1989, Vol. 54, Issue 1, pp. 248–265 [Abstract] - Ivan Rosenberg, Antonín Holý and Milena Masojídková
Phosphonylmethoxyalkyl and phosphonylalkyl derivatives of adenine
1988, Vol. 53, Issue 11, pp. 2753–2777 [Abstract] - Hana Dvořáková, Antonín Holý and Milena Masojídková
Fluorescent analogues of acyclic inhibitors of S-adenosyl-L-homocysteine hydrolase
1988, Vol. 53, Issue 8, pp. 1779–1794 [Abstract] - Antonín Holý, Masahiko Nishizawa, Ivan Rosenberg and Ivan Votruba
The effect of phosphonylmethyl analogs of ribonucleoside 5'-diphosphates on (E. coli) polynucleotide phosphorylase catalyzed reactions
1987, Vol. 52, Issue 12, pp. 3042–3057 [Abstract] - Petr Holý, Martin Bělohradský, Ivan Stibor, Juraj Koudelka, David Šaman, Jana Hodačová, Antonín Holý and Jiří Závada
Crown and azacrown ethers with pendant adenine group
1987, Vol. 52, Issue 12, pp. 2971–2982 [Abstract] - Antonín Holý and Ivan Rosenberg
Synthesis of 9-(2-phosphonylmethoxyethyl)adenine and related compounds
1987, Vol. 52, Issue 11, pp. 2801–2809 [Abstract] - Ivan Rosenberg and Antonín Holý
Synthesis of potential prodrugs and metabolites of 9-(S)-(3-hydroxy-2-phosphonylmethoxypropyl)adenine
1987, Vol. 52, Issue 11, pp. 2792–2800 [Abstract] - Antonín Holý and Ivan Rosenberg
Synthesis of isomeric and enantiomeric O-phosphonylmethyl derivatives of 9-(2,3-dihydroxypropyl)adenine
1987, Vol. 52, Issue 11, pp. 2775–2791 [Abstract] - Ivan Rosenberg and Antonín Holý
Synthesis of phosphonylmethyl analogues of diribonucleoside monophosphates containing modified internucleotide bond
1987, Vol. 52, Issue 10, pp. 2572–2588 [Abstract] - Helmut Pischel, Antonín Holý, Jiří Veselý, Günther Wagner and Dieter Cech
Hydrophilic 1-(carboxymethyl)-5-fluorouracil amides: Preparation and cytostatic activity
1987, Vol. 52, Issue 8, pp. 2061–2069 [Abstract] - Antonín Holý, Joachim König, Jiří Veselý, Dieter Cech, Ivan Votruba and Erik De Clercq
5'-O-Alkyl-5-fluorouridines: Synthesis and biological activity
1987, Vol. 52, Issue 6, pp. 1589–1608 [Abstract] - Maria K. Spassova, Antonín Holý and Milena Masojídková
Ribonucleosides of 3-amino- and 3,5-diaminopyrazole-4-carboxylic acid and their open-chain analogues: Synthesis and reactions
1986, Vol. 51, Issue 7, pp. 1512–1531 [Abstract] - Antonín Holý, Jitka Kohoutová, Aleš Merta and Ivan Votruba
9-(Aminoalkyl)-8-hydroxyadenines: Preparation, mechanism of formation and use in affinity chromatography of S-adenosyl-L-homocysteine hydrolase
1986, Vol. 51, Issue 2, pp. 459–477 [Abstract] - Milena Masojídková, Jaroslav Zajíček, Miloš Buděšínský, Ivan Rosenberg and Antonín Holý
Conformational study on ribonucleoside O-phosphonylmethyl derivatives by 1H NMR spectroscopy
1985, Vol. 50, Issue 8, pp. 1899–1905 [Abstract] - Antonín Holý and Ivan Rosenberg
An improved synthesis of S-adenosyl-L-homocysteine and related compounds
1985, Vol. 50, Issue 7, pp. 1514–1518 [Abstract] - Ivan Rosenberg and Antonín Holý
Phosphonylmethyl analogues of ribonucleoside 2',3'-cyclic phosphates and 2'(3')-nucleotide methyl esters: Synthesis and properties
1985, Vol. 50, Issue 7, pp. 1507–1513 [Abstract] - Antonín Holý, Anita Ludziša, Ivan Votruba, Kateřina Šedivá and Helmut Pischel
Preparation of analogues of cytosine and 2-pyrimidinone nucleosides and their effect on bacterial (Escherichia coli A 19) cytidine aminohydrolase
1985, Vol. 50, Issue 2, pp. 393–417 [Abstract] - Antonín Holý, Ivan Votruba and Erik De Clercq
Structure-activity studies on open-chain analogues of nucleosides: Inhibition of S-adenosyl-L-homocysteine hydrolase and antiviral activity 2. Acid open-chain analogues
1985, Vol. 50, Issue 1, pp. 262–279 [Abstract] - Antonín Holý, Ivan Votruba and Erik De Clercq
Structure-activity studies on open-chain analogues of nucleosides: Inhibition of S-adenosyl-L-homocysteine hydrolase and antiviral activity 1. Neutral open-chain analogues
1985, Vol. 50, Issue 1, pp. 245–261 [Abstract] - Helmut Pischel, Antonín Holý, Jiří Veselý and Günther Wagner
Preparation and biological effects of N-tris(hydroxymethyl)methylaminocarbonylmethyl derivatives of heterocyclic bases
1984, Vol. 49, Issue 11, pp. 2541–2550 [Abstract] - Antonín Holý
Preparation and synthetic utilization of 3-(adenin-9-yl)-2-hydroxyalkanoic acids and their derivatives
1984, Vol. 49, Issue 9, pp. 2148–2166 [Abstract] - Ladislava Šebestová, Ivan Votruba and Antonín Holý
S-adenosine-L-homocysteine hydrolase from Nicotiana tabacum L.: Isolation and properties
1984, Vol. 49, Issue 6, pp. 1543–1551 [Abstract] - Aleš Merta, Ivan Votruba, Jiří Veselý and Antonín Holý
S-adenosyl-L-homocysteine hydrolase from mouse leukemic cells: Isolation and properties
1983, Vol. 48, Issue 9, pp. 2701–2708 [Abstract] - Ivan Votruba, Antonín Holý and Ivan Rosenberg
Affinity chromatography of rat liver S-adenosyl-L-homocysteine hydrolase
1983, Vol. 48, Issue 9, pp. 2549–2557 [Abstract] - Antonín Holý
Preparation of isomeric 3-aminopropylamino derivatives of 9-(RS)-(2,3-dihydroxypropyl)adenine
1983, Vol. 48, Issue 7, pp. 1910–1921 [Abstract] - Jiří Veselý, Ivan Rosenberg and Antonín Holý
Donor activity of 5'-O-phosphonylmethyl analogues of ATP and GTP in the phosphorylation of uridine catalyzed by uridine kinase from mouse leukemic cells
1983, Vol. 48, Issue 6, pp. 1783–1787 [Abstract] - Květa Horská, Ivan Rosenberg, Antonín Holý and Karel Šebesta
5'-O-diphosphorylphosphonylmethylribonucleosides - A new group of DNA-dependent RNA polymerase inhibitors
1983, Vol. 48, Issue 5, pp. 1352–1357 [Abstract] - Ivan Rosenberg and Antonín Holý
Preparation of 2'(3')-O-phosphonylmethyl derivatives of ribonucleosides
1983, Vol. 48, Issue 3, pp. 778–789 [Abstract] - Jiří Veselý, Ivan Rosenberg and Antonín Holý
Inhibition by CTP and UTP analogues of uridine kinase from mouse leukemic cells
1982, Vol. 47, Issue 12, pp. 3464–3469 [Abstract] - Antonín Holý and Ivan Rosenberg
Preparation of 5'-O-phosphonylmethyl analogues of nucleoside-5'-phosphates, 5'-diphosphates and 5'-triphosphates
1982, Vol. 47, Issue 12, pp. 3447–3463 [Abstract] - Antonín Holý
Synthesis of eight stereoisomeric 5-(adenin-9-yl)-2,3,4-trihydroxypentanoic acids
1982, Vol. 47, Issue 11, pp. 2969–2988 [Abstract] - Helmut Pischel, Antonín Holý, Jiří Veselý, Günther Wagner and Dieter Cech
Synthesis and biological activity of N-substituted 5-fluorouracil-1-acetamides
1982, Vol. 47, Issue 10, pp. 2806–2813 [Abstract] - Antonín Holý
Preparation of enantiomeric and racemic 2,3,4,5-tetrahydroxypentyl derivatives of adenine, cytosine and uracil
1982, Vol. 47, Issue 10, pp. 2786–2805 [Abstract] - Antonín Holý, Ivan Votruba and Erik De Clercq
Synthesis and antiviral activity of stereoisomeric eritadenines
1982, Vol. 47, Issue 5, pp. 1392–1407 [Abstract] - Antonín Holý
Stereospecific synthesis of isomeric 4-substituted 9-(2,3-dihydroxybutyl)adenines
1982, Vol. 47, Issue 1, pp. 173–189 [Abstract] - Ivan Votruba and Antonín Holý
Eritadenines - Novel type of potent inhibitors of S-adenosyl-L-homocysteine hydrolase
1982, Vol. 47, Issue 1, pp. 167–172 [Abstract] - Antonín Holý
Preparation of aliphatic analogues of S-adenosyl-L-homocysteine and related compounds
1981, Vol. 46, Issue 12, pp. 3134–3144 [Abstract] - Helmut Pischel, Antonín Holý and Günther Wagner
Preparation of conjugates of uridine with proteins by the imido ester condensation method
1981, Vol. 46, Issue 4, pp. 933–940 [Abstract] - Svetlana Pristašová, Marta Rosenbergová and Antonín Holý
Decyclizing phosphodiesterases associated with plasma membranes of the chick chorioalantois
1981, Vol. 46, Issue 2, pp. 520–524 [Abstract] - Beatrice Schwarz, Dieter Cech, Antonín Holý and Jan Škoda
Preparation, antibacterial effects and enzymatic degradation of 5-fluorouracil nucleosides
1980, Vol. 45, Issue 11, pp. 3217–3230 [Abstract] - Ivan Votruba and Antonín Holý
Inhibition of S-adenosyl-L-homocysteine hydrolase by the aliphatic nucleoside analogue - 9-(S)-(2,3-dihydroxypropyl)adenine
1980, Vol. 45, Issue 11, pp. 3039–3044 [Abstract] - Pavol Kois, Ivan Rosenberg and Antonín Holý
Affinity chromatography of guanyloribonuclease from streptomyces aureofaciens
1980, Vol. 45, Issue 10, pp. 2839–2846 [Abstract] - Pavol Kois and Antonín Holý
Preparation of derivatives of inosine 5'-phosphorothioate for use in affinity chromatography
1980, Vol. 45, Issue 10, pp. 2830–2838 [Abstract] - Antonín Holý and Pavol Kois
Synthesis of 2'(3')-phosphates and 2'(3')-phosphorothioates of 5'-O-carboxymethylinosine and related compounds
1980, Vol. 45, Issue 10, pp. 2817–2829 [Abstract] - Antonín Holý and Erik De Clercq
Preparation, spectral properties and biological activities of 5-bromo-6-methyl-2'-deoxyuridine and 5-iodo-6-methyl-2'-deoxyuridine
1980, Vol. 45, Issue 8, pp. 2364–2370 [Abstract] - Antonina P. Kavunenko and Antonín Holý
Ribonuclease a catalyzed preparative synthesis of dinucleoside monophosphates containing uridine analogues
1980, Vol. 45, Issue 2, pp. 611–616 [Abstract] - Helmut Pischel, Antonín Holý and Günther Wagner
Synthesis of conjugates of 5'-O-carboxymethyl-5-halogeno-2'-deoxyuridines and 5'-O-carboxymethyl-5-halogenouridines with proteins
1980, Vol. 45, Issue 2, pp. 606–610 [Abstract] - Ivan Rosenberg and Antonín Holý
Nucleolytic enzymes of rape seedlings II. Unspecific acid phosphomonoester hydrolase
1979, Vol. 44, Issue 11, pp. 3327–3340 [Abstract] - Helmut Pischel, Antonín Holý and Günther Wagner
Synthesis of conjugates of 1-(carboxymethyl)cytosine and 1-(5-O-carboxymethyl-β-D-arabinofuranosyl)cytosine with proteins
1979, Vol. 44, Issue 10, pp. 3023–3032 [Abstract] - Antonín Holý
Preparation of 9-(β-D-ribofuranosyl)-2-hydroxypurine
1979, Vol. 44, Issue 9, pp. 2846–2853 [Abstract] - Antonín Holý and Miroslav Vaněček
The synthesis and the pharmacological properties of enantiomeric derivatives of 7-(2,3-dihydroxypropyl)theophylline
1979, Vol. 44, Issue 8, pp. 2550–2555 [Abstract] - Antonín Holý
Acid-catalyzed migration of N4-acyl groups in cytosine derivatives
1979, Vol. 44, Issue 6, pp. 1819–1827 [Abstract] - Helmut Pischel, Antonín Holý and Günther Wagner
Synthesis of conjugates of 5-halouracils with proteins using activated esters
1979, Vol. 44, Issue 5, pp. 1634–1641 [Abstract] - Antonín Holý and Ivan Rosenberg
New pyrimidine (uridine) specific cyclizing 2'-ribonucleotidyltransferase and nonspecific decyclizing 2',3'-phosphodiesterase
1979, Vol. 44, Issue 3, pp. 957–975 [Abstract] - Valentina I. Gulyaeva and Antonín Holý
The effect of acceptor modification upon the synthesis of dinucleoside phosphates catalyzed by non-specific ribonucleases of Penicillium claviforme
1979, Vol. 44, Issue 2, pp. 613–625 [Abstract] - Antonín Holý
Synthesis of racemic and optically active erythro- and threo-9-(2,3,4-trihydroxybutyl)adenines and related compounds
1979, Vol. 44, Issue 2, pp. 593–612 [Abstract] - Antonín Holý
Synthesis of new mono- and disubstituted hydroxyalkyl and aminoalkyl derivatives of heterocyclic bases
1978, Vol. 43, Issue 12, pp. 3444–3465 [Abstract] - Jiřina Černá, Antonín Holý and Ivan Rychlík
The stimulation of ribosomal peptidyl transferase by cytosine and its derivatives
1978, Vol. 43, Issue 12, pp. 3279–3291 [Abstract] - Antonín Holý
Synthesis of some 2,3-dihydroxypropyl derivatives of purine bases
1978, Vol. 43, Issue 11, pp. 3103–3117 [Abstract] - Magdaléna Rosinová, Antonín Holý and Eva Zelinková
Substrate specificity of adenosine aminohydrolase from Streptomyces aureofaciens
1978, Vol. 43, Issue 9, pp. 2330–2340 [Abstract] - Alois Čihák and Antonín Holý
Distribution and metabolic transformation of 9-(S)-(2,3-dihydroxypropyl)adenine, an effective virostatic agent, in mice
1978, Vol. 43, Issue 8, pp. 2082–2088 [Abstract] - Antonín Holý
Synthesis of N-(2,3-dihydroxypropyl) derivatives of heterocyclic bases
1978, Vol. 43, Issue 8, pp. 2054–2061 [Abstract] - Antonín Holý and G. Kowollik
Nucleic acid components and their analogues. CXXXI. A simple enzymatic synthesis of nucleoside 5'-phosphates
1970, Vol. 35, Issue 3, pp. 1013–1016 [Abstract]
