Collect. Czech. Chem. Commun. 1983, 48, 2549-2557
https://doi.org/10.1135/cccc19832549

Affinity chromatography of rat liver S-adenosyl-L-homocysteine hydrolase

Ivan Votruba, Antonín Holý and Ivan Rosenberg

Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6

Individual author index pages


Other CCCC articles of these authors

  • Zdeněk Zídek, Antonín Holý, Daniela Franková, Evžen Buchar and Zdeněk Jiřička
    Inhibition of rat adjuvant-induced arthritis by 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA; Adefovir): Immunological, biochemical and hematological correlates
    Symposium Series 1999, Vol. 2, pp. 180–185 [Abstract]
    Published online 2016-05-09 20:59:34
  • Gabriel Birkuš, Ivan Votruba, Antonín Holý and Berta Otová
    HPMPApp as a substrate toward replicative DNA polymerases α, δ and ε
    Symposium Series 1999, Vol. 2, pp. 289–293 [Abstract]
    Published online 2016-05-08 23:33:04
  • Romana Krejčová, Květoslava Horská, Ivan Votruba and Antonín Holý
    Phosphorylation of enantiomers of HPMPG
    Symposium Series 1999, Vol. 2, pp. 286–288 [Abstract]
    Published online 2016-05-08 23:32:58
  • Martina Pressová, Miloš Buděšínský and Ivan Rosenberg
    Spontaneous oligomerization of imidazolidate of 5'-O-phosphonomethyladenosine
    Symposium Series 1999, Vol. 2, pp. 281–282 [Abstract]
    Published online 2016-05-08 23:32:45
  • Petr Alexander, Antonín Holý and Milena Masojídková
    Synthesis of N3-substituted isoguanine derivatives of acyclic nucleotide phosphonates
    Symposium Series 1999, Vol. 2, pp. 263–265 [Abstract]
    Published online 2016-05-08 23:32:12
  • Zlatko Janeba and Antonín Holý
    Synthesis of 8-hydroxy and 8-mercapto derivatives of acyclic adenine nucleoside and nucleotide analogs. Alkylation of 8-substituted adenines
    Symposium Series 1999, Vol. 2, pp. 260–262 [Abstract]
    Published online 2016-05-08 23:32:05
  • Dana Hocková, Milena Masojídková and Antonín Holý
    Significant influence of (N,N-dimethylamino)methylene protection at N6-position of adenine on regioselectivity of alkylations: Selective synthesis of 7-substituted adenines
    Symposium Series 1999, Vol. 2, pp. 257–259 [Abstract]
    Published online 2016-05-08 23:31:57
  • Michal Česnek, Michal Hocek and Antonín Holý
    Cross-coupling reactions of 2-amino-6-halopurine derivatives with organometallic reagents leading to 6-alkylated purine acyclic nucleotide analogues
    Symposium Series 1999, Vol. 2, pp. 255–256 [Abstract]
    Published online 2016-05-08 23:31:50
  • Miroslav Otmar, Ivan Votruba and Antonín Holý
    An alternative synthesis of HPMPC and HPMPA diphosphoryl derivatives
    Symposium Series 1999, Vol. 2, pp. 252–254 [Abstract]
    Published online 2016-05-08 23:31:40
  • Jana Zachová, Ivana Císařová, Miloš Buděšínský, Radek Liboska, Zdeněk Točík and Ivan Rosenberg
    Crystal and solution structure of 5'-O-(guanosine-2'-O-phosphonomethyl)cytidine, an isopolar nonisosteric phosphonate analog of GpC
    Symposium Series 1999, Vol. 2, pp. 233–236 [Abstract]
    Published online 2016-05-08 23:30:57
  • Zdeněk Točík, Ivana Kavenová and Ivan Rosenberg
    Synthetic route to novel isosteric phosphonate analogs of oligonucleotides
    Symposium Series 1999, Vol. 2, pp. 109–113 [Abstract]
    Published online 2016-05-08 20:42:08
  • Dominik Rejman, Radek Liboska, Magdalena Endová, Ivana Kavenová, Zdeněk Točík and Ivan Rosenberg
    Synthesis and hybridization properties of isopolar, nonisosteric phosphonate-based homooligonucleotides
    Symposium Series 1999, Vol. 2, pp. 96–99 [Abstract]
    Published online 2016-05-08 20:41:51
  • Dominik Rejman and Ivan Rosenberg
    Preparation of phosphonate monomers for phosphotriester solid-phase synthesis of isopolar nonisosteric oligonucleotide analogs
    Symposium Series 1999, Vol. 2, pp. 92–95 [Abstract]
    Published online 2016-05-08 20:41:45
  • Šárka Králíková, Miloš Buděšínský, Milena Masojídková, Ivana Kavenová and Ivan Rosenberg
    Synthesis of α-hydroxyphosphonate analogs of ApA and UV spectroscopy study on their complexes with poly(U)
    Symposium Series 1999, Vol. 2, pp. 89–91 [Abstract]
    Published online 2016-05-08 20:41:40
  • Markéta Rinnová and Ivan Rosenberg
    3'-N-phosphonomethyl derivatives of pyrrolidine nucleosides related to L-nucleotides
    Symposium Series 1999, Vol. 2, pp. 60–62 [Abstract]
    Published online 2016-05-08 20:41:05
  • Miroslav Otmar, Milena Masojídková and Antonín Holý
    Synthesis of acyclic 9-deazanucleosides: 9-(2,3-Dihydroxypropyl)-9-deazahypoxanthine
    Symposium Series 1999, Vol. 2, pp. 57–59 [Abstract]
    Published online 2016-05-08 20:40:59
  • Michal Hocek, Martina Havelková, Dalimil Dvořák, Antonín Holý and Ivan Votruba
    Synthesis of 6-phenylpurine bases and nucleosides by Suzuki–Miyaura cross-coupling reactions of 6-chloropurines with substituted phenylboronic acids
    Symposium Series 1999, Vol. 2, pp. 27–30 [Abstract]
    Published online 2016-05-08 20:40:17
  • Václav Vaněk, Miloš Buděšínský, Ivana Kavenová, Markéta Rinnová and Ivan Rosenberg
    Isosteric phosphonate-pyrrolidine-based dinucleoside monophosphate analogues
    Symposium Series 2002, Vol. 5, pp. 391–392 [Abstract]
    Published online 2016-01-25 20:52:06
  • Martina Pressová, Radek Liboska, Miloš Buděšínský, Šárka Králíková, Ivana Kavenová and Ivan Rosenberg
    Oligomerisation aiming at phosphonate analogues of oligoadenylates
    Symposium Series 2002, Vol. 5, pp. 383–384 [Abstract]
    Published online 2016-01-25 20:51:50
  • Ondřej Páv, Miloš Buděšínský and Ivan Rosenberg
    2'-5' Oligoadenylate analogues with C-phosphonate internucleotide linkage
    Symposium Series 2002, Vol. 5, pp. 379–380 [Abstract]
    Published online 2016-01-25 20:51:40
  • Radek Liboska, Miloš Buděšínský, Ivana Kavenová, Ondřej Páv and Ivan Rosenberg
    Hybridization properties of 4'-branched oligonucleotides
    Symposium Series 2002, Vol. 5, pp. 365–366 [Abstract]
    Published online 2016-01-25 20:51:12
  • Marcela Krečmerová, Miloš Buděšínský and Antonín Holý
    Synthesis of optically pure N6-alkyl derivatives of (2R)-3-(adenin-9-yl)-2-hydroxypropanoic acid and related compounds
    Symposium Series 2002, Vol. 5, pp. 358–360 [Abstract]
    Published online 2016-01-25 20:50:59
  • Šárka Králíková, Miloš Buděšínský, Ivana Kavenová and Ivan Rosenberg
    α-Hydroxyphosphonate oligonucleotides: A striking DNA type?
    Symposium Series 2002, Vol. 5, pp. 356–357 [Abstract]
    Published online 2016-01-25 20:50:54
  • Hubert Hřebabecký, Michal Šála, Milena Masojídková and Antonín Holý
    Synthesis of racemic 2-hydroxy-4- and 2-hydroxy-5-(hydroxymethyl)cyclohexyl nucleoside analogues
    Symposium Series 2002, Vol. 5, pp. 332–334 [Abstract]
    Published online 2016-01-25 20:42:39
  • Dana Hocková, Antonín Holý and Milena Masojídková
    Synthesis of acyclic nucleotide analogues derived from 5-substituted 2,4-diamino-6-hydroxypyrimidines
    Symposium Series 2002, Vol. 5, pp. 326–327 [Abstract]
    Published online 2016-01-25 20:42:30
  • Michal Česnek, Antonín Holý and Milena Masojídková
    Isomeric guanidinopurine nucleosides and their analogues
    Symposium Series 2002, Vol. 5, pp. 306–307 [Abstract]
    Published online 2016-01-25 20:41:57
  • Petr Čapek, Miroslav Otmar, Milena Masojídková and Antonín Holý
    Cross-coupling reactions of 2,6-dichloro-9-deazapurine
    Symposium Series 2002, Vol. 5, pp. 304–305 [Abstract]
    Published online 2016-01-25 20:41:51
  • Zdeněk Točík, Radek Liboska, Ivan Barvík, Jr., Miloš Buděšínský, Milena Masojídková, Ivana Kavenová and Ivan Rosenberg
    Isosteric phosphonate mono- and oligonucleotides originating from 4',5'-didehydronucleoside precursors: Some synthetic possibilities and limitations
    Symposium Series 2002, Vol. 5, pp. 208–214 [Abstract]
    Published online 2016-01-25 20:40:13
  • Ivan Rosenberg, Magdalena Endová-Petrová, Šárka Králíková, Radek Liboska, Dominik Rejman and Zdeněk Točík
    From nucleoside phosphonic acids to modified oligonucleotides
    Symposium Series 2002, Vol. 5, pp. 200–207 [Abstract]
    Published online 2016-01-25 20:40:07
  • Miroslav Otmar, Milena Masojídková, Ivan Votruba and Antonín Holý
    Synthesis and cytostatic activity of 2,6-diamino-9-benzyl-9-deazapurine and related compounds
    Symposium Series 2002, Vol. 5, pp. 38–39 [Abstract]
    Published online 2016-01-25 20:38:21
  • Antonín Holý
    Synthetic approaches to "opened-ring" acyclic nucleoside phosphonates – novel type of antivirals
    Symposium Series 2002, Vol. 5, pp. 27–35 [Abstract]
    Published online 2016-01-25 20:38:08
  • Silvie Vrbovská and Antonín Holý
    Novel type of bis-phosphonate congeners of acyclic nucleoside phosphonates
    Symposium Series 2005, Vol. 7, pp. 487–488 [Abstract]
    Published online 2015-11-08 11:59:01
  • Milan Vrabel, Ivan Rosenberg and Michal Hocek
    Synthesis of modified nucleosides and oligonucleotides bearing bipyridine or phenanthroline ligands
    Symposium Series 2005, Vol. 7, pp. 485–486 [Abstract]
    Published online 2015-11-08 11:58:56
  • Václav Vaněk, Miloš Buděšínský and Ivan Rosenberg
    The synthesis of monomers for prolinol-based oligonucleotides
    Symposium Series 2005, Vol. 7, pp. 483–484 [Abstract]
    Published online 2015-11-08 11:58:51
  • Zdeněk Točík, Ivan Barvík, Jr., Miloš Buděšínský and Ivan Rosenberg
    Isosteric phosphonate 3'-O-P-CH2-O-4'C internucleotide linkage: Attempts to get more data on its stereochemistry
    Symposium Series 2005, Vol. 7, pp. 481–482 [Abstract]
    Published online 2015-11-08 11:58:47
  • Markéta Schinkmanová, Ivan Votruba and Antonín Holý
    N6-methyl-AMP hydrolase activates N6-substituted purine ANPs
    Symposium Series 2005, Vol. 7, pp. 463–464 [Abstract]
    Published online 2015-11-08 11:58:20
  • Michal Šála, Hubert Hřebabecký, Milena Masojídková and Antonín Holý
    Synthesis of novel racemic conformationally locked carbocyclic nucleosides
    Symposium Series 2005, Vol. 7, pp. 461–462 [Abstract]
    Published online 2015-11-08 11:58:15
  • Ondřej Páv, Eva Protivínská, Jiří Jiráček and Ivan Rosenberg
    ABEI-labeled 2-5A: A way to chemiluminescent imaging of RNase L binding process
    Symposium Series 2005, Vol. 7, pp. 453–454 [Abstract]
    Published online 2015-11-08 11:58:03
  • Ondřej Pačes and Ivan Rosenberg
    Isopolar, isosteric 4'-substituted 2',5'-oligoadenylates as potential RNase L activators
    Symposium Series 2005, Vol. 7, pp. 447–448 [Abstract]
    Published online 2015-11-08 11:57:54
  • Radim Nencka, Ivan Votruba, Hubert Hřebabecký, Eva Tloušťová, Květa Horská, Milena Masojídková and Antonín Holý
    Design and synthesis of 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase
    Symposium Series 2005, Vol. 7, pp. 441–442 [Abstract]
    Published online 2015-11-08 11:57:40
  • Radek Liboska, Ondřej Páv and Ivan Rosenberg
    Monomers for novel phosphonate oligonucleotides, potential RNase L inhibitors
    Symposium Series 2005, Vol. 7, pp. 437–438 [Abstract]
    Published online 2015-11-08 11:57:30
  • Šárka Králíková, Miloš Buděšínský, Radek Liboska, Ondřej Páv and Ivan Rosenberg
    2',5'-Linked oligo-3'-deoxynucleotide chimeras with chiral α-hydroxyphosphonate internucleotide linkage: Improvement of hybridisation selectivity toward RNA?
    Symposium Series 2005, Vol. 7, pp. 421–422 [Abstract]
    Published online 2015-11-08 11:57:07
  • Petr Kočalka, Markéta Rinnová, Václav Vaněk, Dominik Rejman, Ivan Votruba, Ivana Tomečková, Šárka Králíková, Magdalena Petrová, Ondřej Páv, Radek Pohl, Miloš Buděšínský, Radek Liboska, Zdeněk Točík and Ivan Rosenberg
    Novel nucleoside phosphonic acids-based inhibitors of thymidine phosphorylase
    Symposium Series 2005, Vol. 7, pp. 415–416 [Abstract]
    Published online 2015-11-08 11:56:57
  • Kateřina Hořejší, Radek Pohl and Antonín Holý
    Tricyclic etheno analogs of purines derived from 2-amino-6-chloropurine
    Symposium Series 2005, Vol. 7, pp. 403–404 [Abstract]
    Published online 2015-11-08 11:56:30
  • Petra Doláková, Milena Masojídková and Antonín Holý
    Synthesis and properties of chiral open-ring acyclic nucleoside bisphosphonates
    Symposium Series 2005, Vol. 7, pp. 395–396 [Abstract]
    Published online 2015-11-08 11:56:15
  • Šárka Chalupová and Antonín Holý
    Synthesis of N4-substituted derivatives of (S)-1-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (HPMPC, Cidofovir, Vistide©)
    Symposium Series 2005, Vol. 7, pp. 387–388 [Abstract]
    Published online 2015-11-08 11:56:01
  • Miroslav Hájek, Naděžda Matulová, Ivan Votruba, Antonín Holý and Eva Tloušťová
    Acyclic nucleoside phosphonates and human telomerase inhibition
    Symposium Series 2005, Vol. 7, pp. 373–374 [Abstract]
    Published online 2015-11-08 11:55:35
  • Marcela Krečmerová and Antonín Holý
    Synthesis of C-5 substituted HPMPC (cidofovir) derivatives
    Symposium Series 2005, Vol. 7, pp. 287–290 [Abstract]
    Published online 2015-11-08 11:54:07
  • Miroslav Otmar, Milena Masojídková and Antonín Holý
    Acyclic nucleoside phosphonates containing O-substituted hydroxypyridineamines and diamines as nucleobases
    Symposium Series 2005, Vol. 7, pp. 283–285 [Abstract]
    Published online 2015-11-08 11:54:02
  • Michal Česnek and Antonín Holý
    Biological activity of selected guanidinopurines
    Symposium Series 2005, Vol. 7, pp. 249–251 [Abstract]
    Published online 2015-11-08 11:53:17
  • Peter Šilhár, Radek Pohl, Ivan Votruba and Michal Hocek
    Synthesis and transformations of 6-(hydroxymethyl)purines
    Symposium Series 2005, Vol. 7, pp. 221–224 [Abstract]
    Published online 2015-11-08 11:52:45
  • Radek Pohl, Dominik Rejman, Petr Kočalka and Ivan Rosenberg
    Pyrrolidine nucleotide analogues – conformation study
    Symposium Series 2005, Vol. 7, pp. 165–166 [Abstract]
    Published online 2015-11-08 11:51:48
  • Dominik Rejman, Petr Kočalka, Radek Pohl and Ivan Rosenberg
    Synthesis of 4'-N pyrrolidine nucleosides, nucleotides, and oligonucleotides
    Symposium Series 2005, Vol. 7, pp. 159–163 [Abstract]
    Published online 2015-11-08 11:51:43
  • Ivan Rosenberg, Ivan Barvik, Miloš Buděšínský, Petr Kočalka, Šárka Králíková, Radek Liboska, Ondřej Pačes, Ondřej Páv, Magdalena Petrová, Radek Pohl, Martina Pressová, Dominik Rejman, Ivan Votruba and Zdeněk Točík
    Nucleoside phosphonic acids and related oligonucleotides: Structural diversity vs biological properties
    Symposium Series 2005, Vol. 7, pp. 153–157 [Abstract]
    Published online 2015-11-08 11:51:38
  • Agnieszka Bzowska, Katarzyna Stępniak, Monika Olasek, Maciej Długosz, Beata Wielgus-Kutrowska, Jan Antosiewicz, Antonín Holý, Gertraud Koellner, Albrecht Stroh, Grzegorz Raszewski, Thomas Steiner and Joachim Frank
    Attempts to differentiate subunits of trimeric and hexameric purine nucleoside phosphorylases by crystal structure and solution studies using purine bases, modified purine nucleosides, acyclonucleosides and their phosphonate analogues
    Symposium Series 2005, Vol. 7, pp. 133–142 [Abstract]
    Published online 2015-11-08 11:51:21
  • Jiří Jiráček, Michaela Collinsová, Ivan Rosenberg, Hana Netušilová, Miloš Buděšínský and Timothy A. Garrow
    New inhibitors of human betaine-homocysteine S-methyltransferase
    Symposium Series 2005, Vol. 8, pp. 33–35 [Abstract]
    Published online 2015-11-06 12:02:21
  • Ondřej Sedláček, Radek Pohl and Antonín Holý
    Synthesis of 8-C-substituted 2,6-diaminopurine acyclic nucleoside phosphonates by Negishi cross-coupling
    Symposium Series 2008, Vol. 10, pp. 449–450 [Abstract]
    Published online 2015-10-30 18:44:50
  • Radek Pohl, Miloš Buděšínský, Dominik Rejman, Petr Kočalka and Ivan Rosenberg
    Conformation of pyrrolidine ring in pyrrolidine nucleotide analogues
    Symposium Series 2008, Vol. 10, pp. 435–436 [Abstract]
    Published online 2015-10-30 18:44:27
  • David Mařák, Miroslav Otmar, Martin Dračínský, Ivan Votruba and Antonín Holý
    Nucleosides and nucleotides containing 8-aza-7,9-dideazaxanthine
    Symposium Series 2008, Vol. 10, pp. 426–428 [Abstract]
    Published online 2015-10-30 18:44:11
  • Petr Jansa, Martin Dračínský and Antonín Holý
    Efficient synthesis of "open-ring, close-ring" acyclic nucleoside phosphonates
    Symposium Series 2008, Vol. 10, pp. 360–361 [Abstract]
    Published online 2015-10-30 18:42:02
  • Martin Dračínský, Marcela Krečmerová and Antonín Holý
    Study of chemical stability of antivirally active 5-azacytosine acyclic nucleoside phosphonates using NMR spectroscopy
    Symposium Series 2008, Vol. 10, pp. 338–340 [Abstract]
    Published online 2015-10-30 18:41:11
  • Petra Doláková, Martin Dračínský and Antonín Holý
    Synthesis of acyclic nucleoside diphosphate mimics
    Symposium Series 2008, Vol. 10, pp. 336–337 [Abstract]
    Published online 2015-10-30 18:41:05
  • Jiří Blažek, Antonín Holý, Petra Lipovová, Zita Purkrtová and Blanka Králová
    Analogs of pyrimidin-2-one nucleosides and their enzymatic galactosylation
    Symposium Series 2008, Vol. 10, pp. 322–324 [Abstract]
    Published online 2015-10-30 18:40:37
  • Ondřej Baszczyňski, Antonín Holý, Martin Dračínský and Blanka Klepetářová
    Synthesis of N9-(3-fluoro-2-phosphonomethoxypropyl) (FPMP) derivatives of N6-substituted adenines and 2,6-diaminopurines
    Symposium Series 2008, Vol. 10, pp. 315–316 [Abstract]
    Published online 2015-10-30 18:40:22
  • Radim Nencka, Hubert Hřebabecký, Ivan Votruba, Martin Dračínský and Antonín Holý
    Metalation of 6-halo-2,4-dimethoxypyrimidines as the key step for the synthesis of biologicaly active compounds
    Symposium Series 2008, Vol. 10, pp. 249–253 [Abstract]
    Published online 2015-10-30 18:38:37
  • Karel Pomeisl, Antonín Holý, Ivan Votruba, Radim Nencka and Radek Pohl
    Facile syntheses of pyrimidine acyclic nucleoside phosphonates and their potential evaluation for biomedical applications
    Symposium Series 2008, Vol. 10, pp. 201–205 [Abstract]
    Published online 2015-10-30 18:37:39
  • Marcela Krečmerová, Antonín Holý, Alois Pískala, Graciela Andrei, Robert Snoeck, Jan Balzarini and Erik De Clercq
    New antiviral agent, 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: esters and base-modified derivatives
    Symposium Series 2008, Vol. 10, pp. 196–200 [Abstract]
    Published online 2015-10-30 18:37:33
  • Zlatko Janeba, Antonín Holý and Zdeněk Zídek
    Biological properties of the C-8 substituted analogues of 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA)
    Symposium Series 2011, Vol. 12, pp. 344–346 [Abstract]
  • Tomáš Tichý, Graciela Andrei, Martin Dračínský, Antonín Holý, Jan Balzarini, Robert Snoeck and Marcela Krečmerová
    New amphiphilic prodrugs of adefovir and cidofovir
    Symposium Series 2011, Vol. 12, pp. 477–479 [Abstract]
    Published online 2015-08-20 10:25:04
  • Petr Jansa, Petr Špaček, Antonín Holý, Ivan Votruba and Zlatko Janeba
    Efficient one-pot synthesis of polysubstituted 6-[(1H-1,2,3-triazol-1-yl)methyl]uracils through the "click" protocol
    Symposium Series 2011, Vol. 12, pp. 467–468 [Abstract]
    Published online 2015-08-20 10:24:43
  • Ondřej Šimák, Petr Pachl, Jiří Brynda and Ivan Rosenberg
    Synthesis of new potential inhibitors of 5'-nucleotidases
    Symposium Series 2011, Vol. 12, pp. 462–464 [Abstract]
    Published online 2015-08-20 10:24:33
  • Karel Pomeisl, Antonín Holý and Marcela Krečmerová
    Use of 1,3-dioxolanes in the syntheses of α-branched alkyl and aryl N-9-[2-(phosphonomethoxy)ethyl]purines
    Symposium Series 2011, Vol. 12, pp. 438–440 [Abstract]
    Published online 2015-08-20 10:23:40
  • Magdalena Petrová, Miloš Buděšínský, Blanka Klepetářová and Ivan Rosenberg
    Synthesis and structural assignment of novel 5'-epimeric 3'-deoxy-3',4'-didehydronucleoside-5'-C-phosphonates
    Symposium Series 2011, Vol. 12, pp. 430–432 [Abstract]
    Published online 2015-08-20 10:23:23
  • Marcela Krečmerová, Antonín Holý, Dana Hocková, Martin Dračínský, Dianne T. Keough and Luke W. Guddat
    9-[2-Hydroxy-3-(phosphonomethoxy)propyl] ("iso-HPMP") derivatives of purine bases and their side-chain modified analogues: synthesis and antimalarial activity
    Symposium Series 2011, Vol. 12, pp. 381–382 [Abstract]
    Published online 2015-08-20 10:19:45
  • Petr Jansa, Antonín Holý, Martin Dračínský, Ondřej Baszczyňski, Michal Česnek and Zlatko Janeba
    The unique impact of microwave irradiaton on the chemistry of acyclic nucleoside phosphonates
    Symposium Series 2011, Vol. 12, pp. 347–348 [Abstract]
    Published online 2015-08-20 10:18:28
  • Petr Jansa, Martin Maxmilian Kaiser, Antonín Holý and Zlatko Janeba
    A novel, highly stereoselective synthetic approach for the preparation of substituted 2,5-dihydro-2,5-dihydroxyfurans
    Symposium Series 2011, Vol. 12, pp. 339–341 [Abstract]
    Published online 2015-08-20 10:13:05
  • Martin Dračínský, Petr Jansa, Jana Chocholoušová, Jaroslav Vacek, Soňa Kovačková and Antonín Holý
    The mechanism of isotopic exchange reaction of hydrogen H-5 of uracil derivatives in water and in non-protic solvents
    Symposium Series 2011, Vol. 12, pp. 323–324 [Abstract]
    Published online 2015-08-20 10:12:29
  • Lucie Čechová, Petr Jansa, Michal Šála, Martin Dračínský, Antonín Holý and Zlatko Janeba
    The optimized microwave-assisted decomposition of formamides and its synthetic utility in the amination of purines and pyrimidines
    Symposium Series 2011, Vol. 12, pp. 312–313 [Abstract]
    Published online 2015-08-20 10:12:06
  • Michal Česnek, Petra Břehová, Martin Dračínský, Antonín Holý and Zlatko Janeba
    The efficient synthesis of 2-aryl substituted pyrimidine acyclic nucleoside phosphonates using Liebeskind-Srogl cross-coupling
    Symposium Series 2011, Vol. 12, pp. 310–311 [Abstract]
    Published online 2015-08-20 10:12:01
  • Ondřej Baszczyňski, Petr Jansa, Dana Hocková, Zlatko Janeba, Martin Dračínský, Antonín Holý, Dianne T. Keough, John de Jersey and Luke W. Guddat
    3-Fluoro-2-(phosphonomethoxy)propyl hypoxanthine and guanine derivatives as inhibitors of plasmodial hypoxanthine-guanine-xanthine phosphoribosyltransferases
    Symposium Series 2011, Vol. 12, pp. 302–303 [Abstract]
    Published online 2015-08-20 10:11:43
  • Dana Hocková, Antonín Holý, Michal Česnek, Ondřej Baszczyňski, Tomáš Tichý, Marcela Krečmerová, Zlatko Janeba, Tina S. Skinner-Adams, Lieve Naesens, Dianne T. Keoughd, John de Jersey and Luke W. Guddat
    Acyclic nucleoside phosphonates as inhibitors of hypoxanthine-guanine-xanthine phosphoribosyltransferase: new anti-malarial chemotherapy leads
    Symposium Series 2011, Vol. 12, pp. 171–174 [Abstract]
    Published online 2015-08-20 10:00:19
  • Ondřej Šimák, Petr Pachl, Tomáš Jandušík, Jiří Brynda, Miloš Buděšínský and Ivan Rosenberg
    Bi-substrate inhibitors of human pyrimidine 5’-nucleotidases
    Symposium Series 2014, Vol. 14, pp. 381–382 [Abstract]
    Published online 2015-07-06 23:09:12
  • Michal Šála, Milan Dejmek, Eliška Procházková, Hubert Hřebabecký, Jiří Rybáček, Martin Dračínský, Pavel Novák, Šárka Rosenbergová, Jiří Fukal, Vladimír Sychrovský, Ivan Rosenberg and Radim Nencka
    Novel conformationally locked nucleosides and oligonucleotides based on bicyclo[3.2.1]octane scaffold as a pseudosugar moiety
    Symposium Series 2014, Vol. 14, pp. 379–380 [Abstract]
    Published online 2015-07-06 23:09:07
  • Magdalena Petrová, Miloš Buděšínský, Eva Zborníková, Natalia Panova, Pavel Novák and Ivan Rosenberg
    Activation of human RNase L by 5’-C-phosphonate-modified oligoadenylates
    Symposium Series 2014, Vol. 14, pp. 348–349 [Abstract]
    Published online 2015-07-06 23:07:50
  • Ondřej Páv, Eva Zborníková, Miloš Buděšínský and Ivan Rosenberg
    Phosphanucleosides containing 1-hydroxymethylphospholane 1-oxide ring
    Symposium Series 2014, Vol. 14, pp. 344–345 [Abstract]
    Published online 2015-07-06 23:07:39
  • Ondřej Kostov, Eva Zborníková, Miloš Buděšínský, Pavel Novák and Ivan Rosenberg
    Sulfur-containing phosphonate monomers for oligonucleotide synthesis
    Symposium Series 2014, Vol. 14, pp. 308–309 [Abstract]
    Published online 2015-07-06 23:06:12
  • Martin Maxmilian Kaiser, Pavel Novák, Šárka Rosenbergová, Lenka Poštová-Slavětínská, Ivan Rosenberg and Zlatko Janeba
    Oligonucleotides modified with acyclic nucleoside phosphonate (HPEP) units
    Symposium Series 2014, Vol. 14, pp. 293–294 [Abstract]
    Published online 2015-07-06 23:05:30
  • Martin Křováček, Hana Dvořáková, Ivan Votruba, Ivana Císařová and Dalimil Dvořák*
    6-Alkynylpurines bearing electronacceptor substituents: Preparation, reactivity in cycloaddition reactions and cytostatic activity
    2011, Vol. 76, Issue 12, pp. 1487–1527 [Abstract]
  • Petr Jansa*, Petr Špaček, Ivan Votruba, Petra Břehová, Martin Dračínský, Blanka Klepetářová and Zlatko Janeba
    Efficient one-pot synthesis of polysubstituted 6-[(1H-1,2,3-triazol-1-yl)methyl]uracils through the “click” protocol
    2011, Vol. 76, Issue 9, pp. 1121–1131 [Abstract]
  • Ivana Poláková, Miloš Buděšínský, Zdeněk Točík and Ivan Rosenberg*
    Tetrofuranose nucleoside phosphonic acids: Synthesis and properties
    2011, Vol. 76, Issue 5, pp. 503–536 [Abstract]
  • Ivan Votruba*, Jana Trýznová, Petra Břehová, Eva Tloušťová, Květoslava Horská, Jindřich Fanfrlík, Ondřej Přenosil and Antonín Holý
    Inhibition of human purine nucleoside phosphorylase by tenofovir phosphate congeners
    2010, Vol. 75, Issue 12, pp. 1249–1257 [Abstract]
  • Tomáš Elbert*, Petra Břehová and Antonín Holý
    The preparation of 3H-labeled acyclic nucleoside phosphonates and study of their stability
    2010, Vol. 75, Issue 7, pp. 757–766 [Abstract]
  • Zlatko Janeba*, Milena Masojídková and Antonín Holý
    Alternative synthesis of 9-{3-[(diisopropoxyphosphoryl)methoxy]-2-hydroxypropyl}adenine and its free phosphonates substituted at the C-8 position of purine base
    2010, Vol. 75, Issue 3, pp. 371–381 [Abstract]
  • Michal Šála, Hubert Hřebabecký*, Martin Dračínský, Milena Masojídková, Armando M. De Palma, Johan Neyts and Antonín Holý
    Synthesis of novel racemic carbocyclic nucleosides derived from 5,6-disubstituted norbornene
    2010, Vol. 75, Issue 1, pp. 1–20 [Abstract]
  • Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
    New carbocyclic nucleoside analogues built on a bicyclo[2.2.2]octane-2,2-dimethanol template
    2009, Vol. 74, Issue 9, pp. 1425–1441 [Abstract]
  • Vojtěch Balšánek, Lucie Tichotová, Jiří Kuneš, Marcel Špulák, Milan Pour*, Ivan Votruba and Vladimír Buchta
    Cytostatic tetrazole–butenolide conjugates: linking tetrazole and butenolide rings via stille coupling and biological activity of the target substances
    2009, Vol. 74, Issue 7-8, pp. 1161–1178 [Abstract]
  • Dominik Rejman*, Petr Kočalka, Radek Pohl, Zdeněk Točík and Ivan Rosenberg*
    Synthesis and hybridization of oligonucleotides modified at AMP sites with adenine pyrrolidine phosphonate nucleotides
    2009, Vol. 74, Issue 6, pp. 935–955 [Abstract]
  • Hubert Hřebabecký*, Martin Dračínský, Armando M. De Palma, Johan Neyts and Antonín Holý
    Synthesis of novel carbocyclic nucleoside analogues derived from 7-oxabicyclo[2.2.1]heptane-2-methanol
    2009, Vol. 74, Issue 3, pp. 487–502 [Abstract]
  • Hubert Hřebabecký*, Martin Dračínský, Armando M. De Palma, Johan Neyts and Antonín Holý
    Synthesis of novel racemic carbocyclic nucleoside analogues derived from 4,8-dioxatricyclo[4.2.1.03,7]nonane-9-methanol and 4-oxatricyclo[4.3.1.03,7]decane-10-methanol, compounds with activity against Coxsackie viruses
    2009, Vol. 74, Issue 3, pp. 469–485 [Abstract]
  • Markéta Schinkmanová*, Ivan Votruba, Riri Shibata, Bin Han, Xiaohong Liu, Tomas Cihlar and Antonín Holý
    Human N6-Methyl-AMP/DAMP Aminohydrolase (Abacavir 5'-Monophosphate Deaminase) is Capable of Metabolizing N6-Substituted Purine Acyclic Nucleoside Phosphonates
    2008, Vol. 73, Issue 2, pp. 275–291 [Abstract]
  • Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
    Synthesis of Novel Carbocyclic Nucleoside Analogues Containing Bicyclo[2.2.1]hept-2-ene-2-methanol
    2008, Vol. 73, Issue 1, pp. 44–58 [Abstract]
  • Ondřej Pačes, Zdeněk Točík* and Ivan Rosenberg*
    A New Linker for Solid-Phase Synthesis of Oligonucleotides with Terminal Phosphate Group
    2008, Vol. 73, Issue 1, pp. 32–43 [Abstract]
  • Milan Dejmek, Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
    Synthesis of Novel Carbocyclic Nucleoside Analogues Derived from 2-(Hydroxymethyl)bicyclo[2.2.1]heptane
    2007, Vol. 72, Issue 11, pp. 1523–1544 [Abstract]
  • Hubert Hřebabecký*, Martin Dračínský and Antonín Holý
    Synthesis of Novel Carbocyclic Nucleosides and Pro-Tides Derived from 4-Oxatricyclo[4.2.1.03,7]nonane-9-methanol
    2007, Vol. 72, Issue 10, pp. 1331–1349 [Abstract]
  • Silvie Vrbková*, Martin Dračínský and Antonín Holý
    Bifunctional Acyclic Nucleoside Phosphonates: 2. Symmetrical 2-{[Bis(phosphono)methoxy]methyl}ethyl Derivatives of Purines and Pyrimidines
    2007, Vol. 72, Issue 7, pp. 965–983 [Abstract]
  • Marcela Krečmerová*, Antonín Holý and Milena Masojídková
    Pyrimidine Acyclic Nucleotide Analogues with Aromatic Substituents in C-5 Position
    2007, Vol. 72, Issue 7, pp. 927–951 [Abstract]
  • Michal Česnek*, Milena Masojídková, Antonín Holý, Veronika Šolínová, Dušan Koval and Václav Kašička
    Synthesis and Properties of 2-Guanidinopurines
    2006, Vol. 71, Issue 9, pp. 1303–1319 [Abstract]
  • Michal Pechar*, Alena Braunová, Vladimír Šubr, Karel Ulbrich and Antonín Holý
    Polymeric Conjugates of 9-[2-(Phosphonomethoxy)ethyl]purine with Potential Antiviral and Cytostatic Activity
    2006, Vol. 71, Issue 8, pp. 1211–1220 [Abstract]
  • Hubert Hřebabecký*, Milena Masojídková, Martin Dračínský and Antonín Holý
    Synthesis of Novel Conformationally Locked Carbocyclic Nucleosides Derived from 3-(Hydroxymethyl)bicyclo[2.2.1]heptane-2,5-diol
    2006, Vol. 71, Issue 6, pp. 871–888 [Abstract]
  • Tuomas Lönnberg, Šárka Králíková, Ivan Rosenberg and Harri Lönnberg*
    Kinetics and Mechanisms for the Isomerization of Internucleosidic 3'-O-P-CH2-5' and 3'-O-P-CH(OH)-5' Linkages to Their 2',5'-Counterparts
    2006, Vol. 71, Issue 6, pp. 859–870 [Abstract]
  • Peter Šilhár, Radek Pohl, Ivan Votruba, Blanka Klepetářová and Michal Hocek*
    Synthesis of 6-Amino-, 6-Methyl- and 6-Aryl-2-(hydroxymethyl)purine Bases and Nucleosides
    2006, Vol. 71, Issue 6, pp. 788–803 [Abstract]
  • Michal Šála, Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
    Synthesis of Novel Racemic Conformationally Locked Carbocyclic Nucleosides Derived from 7-Substituted Bicyclo[2.2.1]hept-5-ene-2,2-dimethanols
    2006, Vol. 71, Issue 5, pp. 635–649 [Abstract]
  • Karel Pomeisl*, Ivan Votruba, Antonín Holý and Radek Pohl
    Syntheses of Base and Side-Chain Modified Pyrimidine 1-[2-(Phosphonomethoxy)propyl] Derivatives as Potent Inhibitors of Thymidine Phosphorylase (PD-ECGF) from SD-Lymphoma
    2006, Vol. 71, Issue 4, pp. 595–624 [Abstract]
  • Marcela Krečmerová*, Milena Masojídková and Antonín Holý
    Preparation of C-5 Substituted Cidofovir Derivatives
    2006, Vol. 71, Issue 4, pp. 579–594 [Abstract]
  • Silvie Vrbovská*, Antonín Holý, Radek Pohl and Milena Masojídková
    Bifunctional Acyclic Nucleoside Phosphonates. 1. Symmetrical 1,3-Bis[(phosphonomethoxy)propan-2-yl] Derivatives of Purines and Pyrimidines
    2006, Vol. 71, Issue 4, pp. 543–566 [Abstract]
  • Kateřina Hořejší, Radek Pohl and Antonín Holý*
    Tricyclic Purine Analogs Derived from 2-Amino-6-chloropurine and 2,6-Diaminopurine and Their Methylated Quaternary Salts
    2006, Vol. 71, Issue 1, pp. 77–90 [Abstract]
  • Květoslava Horská, Ivan Votruba* and Antonín Holý
    Interaction of Phosphates of the Acyclic Nucleoside Phosphonates with Nucleoside Diphosphate Kinase from Yeast and Bovine Liver
    2006, Vol. 71, Issue 1, pp. 35–43 [Abstract]
  • Šárka Chalupová*, Antonín Holý and Milena Masojídková
    Synthesis of N4-Substituted Derivatives of 1-[2-(Phosphonomethoxy)ethyl]cytosine and Its Diisopropyl Ester as a Model Reaction for the Synthesis of N4-Substituted Derivatives of Cidofovir
    2005, Vol. 70, Issue 12, pp. 2066–2074 [Abstract]
  • Šárka Chalupová*, Antonín Holý and Milena Masojídková
    Synthesis of Some N4-Substituted Derivatives of 1-[(S)-3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine (HPMPC, Cidofovir)
    2005, Vol. 70, Issue 12, pp. 2053–2065 [Abstract]
  • Peter Šilhár, Radek Pohl, Ivan Votruba and Michal Hocek*
    Synthesis of 2-Substituted 6-(Hydroxymethyl)purine Bases and Nucleosides
    2005, Vol. 70, Issue 10, pp. 1669–1695 [Abstract]
  • Karel Pomeisl*, Radek Pohl, Antonín Holý and Ivan Votruba
    Simple Transformation of Thymine 1-[3-Hydroxy-2-(phosphonomethoxy)propyl] Derivatives to Their 1-[3-Fluoro-2-(phosphonomethoxy)propyl] Counterparts
    2005, Vol. 70, Issue 9, pp. 1465–1481 [Abstract]
  • Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
    Synthesis of Novel Conformationally Locked Carbocyclic Nucleosides Derived from 5,5- and 6,6-Bis(hydroxymethyl)bicyclo[2.2.1]heptan-2-ol
    2005, Vol. 70, Issue 4, pp. 519–538 [Abstract]
  • Pavel Turek, Martin Kotora*, Michal Hocek* and Ivan Votruba
    Novel Method for Preparation of Highly Substituted 6-Arylpurines by Reactions of 6-Alkynylpurines with Zirconacyclopentadienes
    2005, Vol. 70, Issue 3, pp. 339–349 [Abstract]
  • Dana Hocková*, Milena Masojídková and Antonín Holý
    Sonogashira Cross-Coupling in the Synthesis of Acyclic Nucleoside Phosphonates: Preparation of 6-[(Phosphonomethoxy)alkynyl]- and 6-[(Phosphonomethoxy)alkyl]pyrimidines
    2005, Vol. 70, Issue 2, pp. 247–258 [Abstract]
  • Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
    Synthesis of Racemic 9-(6- and 2,6-Substituted 9H-Purin-9-yl)-5-oxatricyclo[4.2.1.03,7]nonane-3-methanols, Novel Conformationally Locked Carbocyclic Nucleosides
    2005, Vol. 70, Issue 1, pp. 103–123 [Abstract]
  • Petr Nauš, Ivan Votruba and Michal Hocek*
    Covalent Analogues of DNA Base-Pairs and Triplets VII. Synthesis and Cytostatic Activity of Bis(purin-6-yl)acetylene and -diacetylene Nucleosides
    2004, Vol. 69, Issue 10, pp. 1955–1970 [Abstract]
  • Marcela Krečmerová*, Milena Masojídková and Antonín Holý
    Synthesis of N9- and N7-[2-Hydroxy-3-(phosphonomethoxy)propyl] Derivatives of N6-Substituted Adenines, 2,6-Diaminopurines and Related Compounds
    2004, Vol. 69, Issue 10, pp. 1889–1913 [Abstract]
  • Michal Šála, Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
    Synthesis of Racemic 2-Hydroxy-4- and 2-Hydroxy-5-(hydroxymethyl)cyclohexane Pyrimidine C-Nucleoside Analogues
    2004, Vol. 69, Issue 4, pp. 918–932 [Abstract]
  • Alois Pískala*, Naeem B. Hanna, Milena Masojídková, Pavel Fiedler and Ivan Votruba
    Synthesis of N4-Amino and N4-Hydroxy Derivatives of 5-Azacytidine. A Facile Rearrangement of the N4-Amino Derivative to 5-(3-β-D-Ribofuranosylureido)-1H-1,2,4-triazole
    2004, Vol. 69, Issue 4, pp. 905–917 [Abstract]
  • Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
    Synthesis of Purine Nucleoside Analogues Derived from Carbocyclic 5-C-(Hydroxymethyl)hexopyranoses
    2004, Vol. 69, Issue 2, pp. 435–452 [Abstract]
  • Michal Česnek*, Antonín Holý and Milena Masojídková
    New 2-Alkynyl Derivatives of the Acyclic Nucleoside 9-(2,3-Dihydroxypropyl)adenine and Their 6-Guanidinopurine Counterparts as Potential Effectors of Adenosine Receptors
    2003, Vol. 68, Issue 11, pp. 2201–2218 [Abstract]
  • Marcela Krečmerová*, Miloš Buděšínský, Milena Masojídková and Antonín Holý
    Synthesis of Optically Active N6-Alkyl Derivatives of (R)-3-(Adenin-9-yl)-2-hydroxypropanoic Acid and Related Compounds
    2003, Vol. 68, Issue 5, pp. 931–950 [Abstract]
  • Petr Čapek, Miroslav Otmar*, Milena Masojídková, Ivan Votruba and Antonín Holý
    A Facile Synthesis of 9-Deaza Analogue of Olomoucine
    2003, Vol. 68, Issue 4, pp. 779–791 [Abstract]
  • Hubert Hřebabecký*, Milena Masojídková and Antonín Holý
    Synthesis of Racemic 2-Hydroxy-4- and 2-Hydroxy-5-(hydroxymethyl)cyclohexane Nucleoside Analogues
    2002, Vol. 67, Issue 11, pp. 1681–1699 [Abstract]
  • Dominik Rejman, Šárka Králíková, Zdeněk Točík, Radek Liboska and Ivan Rosenberg*
    Selective Cleavage of O-(Dimethoxytrityl) Protecting Group with Sodium Periodate
    2002, Vol. 67, Issue 4, pp. 502–508 [Abstract]
  • Michal Hocek*, Antonín Holý and Hana Dvořáková
    Cytostatic 6-Arylpurine Nucleosides IV. Synthesis of 2-Substituted 6-Phenylpurine Ribonucleosides
    2002, Vol. 67, Issue 3, pp. 325–335 [Abstract]
  • Gabriel Birkuš, Ivan Votruba*, Miroslav Otmar and Antonín Holý
    Interactions of 1-[(S)-3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine (Cidofovir) Diphosphate with DNA Polymerases α, δ and ε*
    2001, Vol. 66, Issue 11, pp. 1698–1706 [Abstract]
  • Antonín Holý*, Ivan Votruba, Eva Tloušťová and Milena Masojídková
    Synthesis and Cytostatic Activity of N-[2-(Phosphonomethoxy)alkyl] Derivatives of N6-Substituted Adenines, 2,6-Diaminopurines and Related Compounds
    2001, Vol. 66, Issue 10, pp. 1545–1592 [Abstract]
  • Zlatko Janeba*, Antonín Holý and Milena Masojídková
    Transformation of 8-[(2-Hydroxyalkyl)sulfanyl]adenines to 6-Amino-7H-purin-8(9H)-one Derivatives
    2001, Vol. 66, Issue 9, pp. 1393–1406 [Abstract]
  • Hubert Hřebabecký* and Antonín Holý
    Synthesis of Carba Analogues of Deoxy-4-C-(hydroxymethyl)hexopyranoses, Intermediates in the Synthesis of Carbocyclic Nucleosides
    2001, Vol. 66, Issue 5, pp. 785–798 [Abstract]
  • Zlatko Janeba*, Antonín Holý and Milena Masojídková
    Synthesis of 8-Amino- and N-Substituted 8-Aminoadenine Derivatives of Acyclic Nucleoside and Nucleotide Analogs
    2001, Vol. 66, Issue 3, pp. 517–532 [Abstract]
  • Miroslav Otmar*, Lucie Poláková, Milena Masojídková and Antonín Holý
    A Facile Synthesis of Azetidin-2-ylphosphonic Acid and Its 1-Alkyl Derivatives
    2001, Vol. 66, Issue 3, pp. 507–516 [Abstract]
  • Miroslav Otmar*, Milena Masojídková, Ivan Votruba and Antonín Holý
    An Alternative Synthesis of HPMPC and HPMPA Diphosphoryl Derivatives
    2001, Vol. 66, Issue 3, pp. 500–506 [Abstract]
  • Michal Hocek*, Antonín Holý, Ivan Votruba and Hana Dvořáková
    Cytostatic 6-Arylpurine Nucleosides III. Synthesis and Structure-Activity Relationship Study in Cytostatic Activity of 6-Aryl-, 6-Hetaryl- and 6-Benzylpurine Ribonucleosides
    2001, Vol. 66, Issue 3, pp. 483–499 [Abstract]
  • Petr Alexander*, Antonín Holý, Miloš Buděšínský and Milena Masojídková
    Synthesis of Acyclic Nucleotide Analogues Derived from N3-Substituted Isoguanine
    2000, Vol. 65, Issue 11, pp. 1713–1725 [Abstract]
  • Zlatko Janeba*, Antonín Holý and Milena Masojídková
    Synthesis of Acyclic Nucleoside and Nucleotide Analogs Derived from 6-Amino-7H-purine-8(9H)-thione and 8-(Methylsulfanyl)adenine
    2000, Vol. 65, Issue 11, pp. 1698–1712 [Abstract]
  • Michal Hocek*, Antonín Holý, Ivan Votruba and Hana Dvořáková
    Cytostatic 6-Arylpurine Nucleosides II. Synthesis of Sugar-Modified Derivatives: 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-, 9-(5-Deoxy-β-D-ribofuranosyl)- and 9-(2,3-Dihydroxypropyl)-6-phenylpurines
    2000, Vol. 65, Issue 11, pp. 1683–1697 [Abstract]
  • Romana Krejčová, Květoslava Horská, Ivan Votruba* and Antonín Holý
    Phosphorylation of Purine (Phosphonomethoxy)alkyl Derivatives by Mitochondrial AMP Kinase (AK2 Type) from L1210 Cells
    2000, Vol. 65, Issue 10, pp. 1653–1668 [Abstract]
  • Michal Česnek, Michal Hocek* and Antonín Holý
    Synthesis of Acyclic Nucleotide Analogues Derived from 2-Amino-6-C-substituted Purines via Cross-Coupling Reactions of 2-Amino-9-{2-[(diisopropoxyphosphoryl)methoxy]ethyl}-6-halopurines with Diverse Organometallic Reagents
    2000, Vol. 65, Issue 8, pp. 1357–1373 [Abstract]
  • Zlatko Janeba*, Antonín Holý and Milena Masojídková
    Synthesis of Acyclic Nucleoside and Nucleotide Analogs Derived from 6-Amino-7H-purin-8(9H)-one
    2000, Vol. 65, Issue 7, pp. 1126–1144 [Abstract]
  • Kateřina Meszárosová, Antonín Holý* and Milena Masojídková
    Synthesis of Acyclic Adenine 8,N-Anhydronucleosides
    2000, Vol. 65, Issue 7, pp. 1109–1125 [Abstract]
  • Hubert Hřebabecký* and Antonín Holý
    Synthesis of Carbocyclic 4'-C-Hydroxymethyl Analogues of Azidodeoxythymidine, Deoxythymidine, Deoxydidehydrothymidine and Thymidine Carba Analogue with Fused Oxetane Ring
    2000, Vol. 65, Issue 3, pp. 395–406 [Abstract]
  • Hubert Hřebabecký* and Antonín Holý
    Synthesis of Carba Analogues of 2'-Deoxy-4'-C-(hydroxymethyl)nucleosides
    1999, Vol. 64, Issue 9, pp. 1485–1496 [Abstract]
  • Dana Hocková*, Milena Masojídková and Antonín Holý
    7-(1-Cyanobut-3-en-1-yl)-N6-[(N,N-dimethylamino)methylene]adenine as a Starting Compound for the Synthesis of α-Branched Acyclic Analogues of N7-Isomer of Adenosine
    1999, Vol. 64, Issue 8, pp. 1316–1324 [Abstract]
  • Claudia A. Blindauer, Antonín Holý and Helmut Sigel*
    Metal Ion-Binding Properties of the Nucleotide Analogue 1-[2-(Phosphonomethoxy)ethyl]cytosine (PMEC) in Aqueous Solution
    1999, Vol. 64, Issue 4, pp. 613–632 [Abstract]
  • Romana Krejčová, Květoslava Horská, Ivan Votruba* and Antonín Holý
    Isoenzymes of GMP Kinase from L1210 Cells: Isolation and Characterization
    1999, Vol. 64, Issue 3, pp. 559–570 [Abstract]
  • Antonín Holý*, Miloš Buděšínský, Jaroslav Podlaha and Ivana Císařová
    Synthesis of Quaternary 1-[2-(Phosphonomethoxy)ethyl] Derivatives of 2,4-Diaminopyrimidine and Related Acyclic Nucleotide Analogs
    1999, Vol. 64, Issue 2, pp. 242–256 [Abstract]
  • Michal Hocek* and Antonín Holý
    Perfluoroalkylation of 6-Iodopurines by Trimethyl(perfluoroalkyl)silanes. Synthesis of 6-(Perfluoroalkyl)purine Bases, Nucleosides and Acyclic Nucleotide Analogues
    1999, Vol. 64, Issue 2, pp. 229–241 [Abstract]
  • Hana Dvořáková, Dalimil Dvořák and Antonín Holý
    Synthesis of Acyclic Nucleotide Analogues Derived from 6-(sec- or tert-Alkyl)purines via Coupling of 6-Chloropurine Derivatives with Organocuprates
    1998, Vol. 63, Issue 12, pp. 2065–2074 [Abstract]
  • Hubert Hřebabecký, Milena Masojídková and Antonín Holý
    Synthesis of Carba Analogues of Deoxy-4-C-(hydroxymethyl)pentofuranoses, Intermediates in the Synthesis of Carbocyclic Nucleosides
    1998, Vol. 63, Issue 12, pp. 2044–2064 [Abstract]
  • Gabriel Birkuš, Pavel Kramata, Ivan Votruba, Berta Otová, Miroslav Otmar and Antonín Holý
    Nonproteolyzed Form of DNA-Polymerase ε from T-Cell Spontaneous Lymphoma of Sprague-Dawley Inbred Rat: Isolation and Characterization
    1998, Vol. 63, Issue 5, pp. 723–731 [Abstract]
  • Hubert Hřebabecký and Antonín Holý
    Preparation of Thymidine-4'-C-carboxylic Acid and Its Derivatives
    1997, Vol. 62, Issue 7, pp. 1128–1135 [Abstract]
  • Hubert Hřebabecký, Jan Balzarini and Antonín Holý
    Preparation of Chloro and Sulfanyl Derivatives of 1-(2-Deoxy-4-C-hydroxymethyl-α-L-threo-Pentofuranosyl)uracil
    1997, Vol. 62, Issue 7, pp. 1114–1127 [Abstract]
  • Hubert Hřebabecký, Miloš Buděšínský, Milena Masojídková, Zdeněk Havlas and Antonín Holý
    1-(3,5-O-Alkylidene-2-deoxy-4-C-hydroxymethyl-α-L-threo-pentofuranosyl)uracils
    1997, Vol. 62, Issue 6, pp. 957–970 [Abstract]
  • Dana Hocková and Antonín Holý
    Synthesis of Some "Abbreviated" NAD+ Analogues
    1997, Vol. 62, Issue 6, pp. 948–956 [Abstract]
  • Lenka Olšanská, Tomas Cihlar, Ivan Votruba* and Antonín Holý
    Transport of Adefovir (PMEA) in Human T-Lymphoblastoid Cells
    1997, Vol. 62, Issue 5, pp. 821–828 [Abstract]
  • Michal Hocek, Milena Masojídková and Antonín Holý
    Synthesis of Acyclic Nucleotide Analogues Derived from 6-Hetarylpurines via Cross-Coupling Reactions of 9-[2-(Diethoxyphosphonylmethoxy)ethyl]-6-iodopurine with Hetaryl Organometallic Reagents
    1997, Vol. 62, Issue 1, pp. 136–146 [Abstract]
  • Jaroslav Zajíček, Ivan Rosenberg, Radek Liboska, Zdeněk Točík, G. Victor Fazakerley, Wilhelm Guschlbauer and Antonín Holý
    Conformational Studies on Diribonucleoside Monophosphate Analogs Containing a Nonisosteric, Isopolar, Phosphonate-Based Internucleotide Linkage
    1997, Vol. 62, Issue 1, pp. 83–98 [Abstract]
  • Pavel Kramata, Gabriel Birkuš, Miroslav Otmar, Ivan Votruba and Antonín Holý
    Structural features of acyclic nucleotide analogs conferring inhibitory effects on cellular replicative DNA polymerases
    1996, Vol. 61, Special Issue, pp. S188–S191 [Abstract]
  • Antonín Holý, Zdeněk Zídek and Ivan Votruba
    Inhibition of murine lymphocyte proliferation by N6-substituted acyclic purine nucleoside phosphonates
    1996, Vol. 61, Special Issue, pp. S182–S187 [Abstract]
  • Magdalena Endová, Milena Masojídková and Ivan Rosenberg
    Synthesis of some derivatives of 1-[2-deoxy-3,5-O-(1-diethylphosphono)alkylidene-β-D-threo-pentofuranosyl]thymine substituted in the ω-position of the alkylidene moiety
    1996, Vol. 61, Special Issue, pp. S167–S170 [Abstract]
  • Romana Krejčová, Květoslava Horská, Ivan Votruba and Antonín Holý
    Phosphorylation of phosphonomethoxyalkylguanines by GMP-kinase isoenzymes
    1996, Vol. 61, Special Issue, pp. S134–S136 [Abstract]
  • Lan Dinh Chu, Hubert Hřebabecký and Antonín Holý
    A new synthesis of 2,2'-anhydro-5-alkyl/aryl-3-glycosyluracils
    1996, Vol. 61, Special Issue, pp. S129–S131 [Abstract]
  • Ivan Rosenberg and Radek Liboska
    A novel class of PME and HPMP derivatives of nucleobases modified in the heterocyclic moiety
    1996, Vol. 61, Special Issue, pp. S126–S128 [Abstract]
  • Šárka Králíková and Ivan Rosenberg
    The addition of phosphorous acid esters on the carbonyl group of 3'-ketonucleosides and nucleoside-5'-aldehydes: Synthesis of novel class of nucleotide analogs
    1996, Vol. 61, Special Issue, pp. S124–S125 [Abstract]
  • Dominik Rejman and Ivan Rosenberg
    Synthesis of 2'-alkoxy and 2'-aryloxy derivatives of 9-(2-phosphonomethoxyethyl)adenine (PMEA) and related compounds
    1996, Vol. 61, Special Issue, pp. S122–S123 [Abstract]
  • Roman Wágner, Dalimil Dvořák and Antonín Holý
    New application of the Stille coupling in the synthesis of 5-substituted uracils
    1996, Vol. 61, Special Issue, pp. S118–S119 [Abstract]
  • Zlatko Janeba and Antonín Holý
    Intramolecular cyclization of some (S)-9-(3-hydroxy-2-phosphonomethoxypropyl)adenine derivatives
    1996, Vol. 61, Special Issue, pp. S116–S117 [Abstract]
  • Ivan Rosenberg and Šárka Králíková
    A simple synthetic route to the preparation of 2-(1-phosphonoalkoxy)ethyl derivatives of heterocyclic bases as novel nucleotide analogs related to PMEA
    1996, Vol. 61, Special Issue, pp. S81–S84 [Abstract]
  • Zdeněk Točík, Iva Kavenová and Ivan Rosenberg
    Preparation of 4'-phosphonomethoxy derivatives of nucleosides: Addition of hydroxymethanephosphonic acid dialkyl esters to 4',5'-didehydronucleosides
    1996, Vol. 61, Special Issue, pp. S76–S80 [Abstract]
  • Michal Hocek and Antonín Holý
    Acyclic nucleotide analogues derived from 6-(1-aminoalkyl)purines
    1996, Vol. 61, Special Issue, pp. S55–S58 [Abstract]
  • Dana Hocková and Antonín Holý
    "Abbreviated" NAD+ analogues containing a phosphonate function
    1996, Vol. 61, Special Issue, pp. S52–S54 [Abstract]
  • Miroslav Otmar, Milena Masojídková and Antonín Holý
    Two synthetic approaches to 9-deaza analogues of 9-(2,3-dihydroxypropyl)adenine (DHPA)
    1996, Vol. 61, Special Issue, pp. S49–S51 [Abstract]
  • Dana Hocková, Milena Masojídková and Antonín Holý
    "Abbreviated" NAD+ Analogues Containinga Phosphonate Function
    1996, Vol. 61, Issue 10, pp. 1538–1548 [Abstract]
  • Michal Hocek, Milena Masojídková, Antonín Holý, Graciela Andrei, Robert Snoeck, Jan Balzarini and Erik De Clercq
    Synthesis and Antiviral Activity of Acyclic Nucleotide Analogues Derived from 6-(Aminomethyl)purines and Purine-6-carboxamidines
    1996, Vol. 61, Issue 10, pp. 1525–1537 [Abstract]
  • Radek Liboska, Milena Masojídková and Ivan Rosenberg
    Carbocyclic Phosphonate-Based Nucleotide Analogs Related to PMEA II. Racemic cis-Configured Derivatives
    1996, Vol. 61, Issue 5, pp. 778–790 [Abstract]
  • Marcela Krečmerová, Hubert Hřebabecký and Antonín Holý
    Synthesis of 5-Phenylcytosine Nucleoside Derivatives
    1996, Vol. 61, Issue 4, pp. 645–655 [Abstract]
  • Marcela Krečmerová, Hubert Hřebabecký and Antonín Holý
    Preparation of 5-Benzyluracil and 5-Benzylcytosine Nucleosides as Potential Inhibitors of Uridine Phosphorylase
    1996, Vol. 61, Issue 4, pp. 627–644 [Abstract]
  • Marcela Krečmerová, Hubert Hřebabecký, Milena Masojídková and Antonín Holý
    2',3'-Dideoxy- and 3'-Azido-2',3'-dideoxynucleosides of 5-Phenyl-2(1H)-pyrimidinone. Preparation of 2',3'-Dideoxypentofuranoses
    1996, Vol. 61, Issue 3, pp. 478–488 [Abstract]
  • Marcela Krečmerová, Hubert Hřebabecký, Milena Masojídková and Antonín Holý
    Synthesis of 5-Phenyl-2(1H)-pyrimidinone Nucleosides
    1996, Vol. 61, Issue 3, pp. 458–477 [Abstract]
  • Zlatko Janeba, Antonín Holý, Hana Votavová and Milena Masojídková
    Intramolecular Cyclization of Some Acyclic Nucleoside Analogs
    1996, Vol. 61, Issue 3, pp. 442–457 [Abstract]
  • Radek Liboska, Milena Masojídková and Ivan Rosenberg
    Carbocyclic Phosphonate-Based Nucleotide Analogs Related to PMEA. I. Racemic trans-Configured Derivatives
    1996, Vol. 61, Issue 2, pp. 313–332 [Abstract]
  • Pavel Kramata, Jaroslav Černý, Gabriel Birkuš, Ivan Votruba, Berta Otová and Antonín Holý
    DNA-Polymerases α, δ and ε from T-Cell Spontaneous Lymphoblastic Leukemia of Sprague-Dawley Inbred Rat: Isolation and Characterization
    1995, Vol. 60, Issue 9, pp. 1555–1572 [Abstract]
  • Antonín Holý, Hana Dvořáková and Milena Masojídková
    Synthesis of Enantiomeric N-(2-Phosphonomethoxypropyl) Derivatives of Purine and Pyrimidine Bases. II. The Synthon Approach
    1995, Vol. 60, Issue 8, pp. 1390–1409 [Abstract]
  • Michal Hocek and Antonín Holý
    A Facile Synthesis of 6-Cyanopurine Bases
    1995, Vol. 60, Issue 8, pp. 1386–1389 [Abstract]
  • Antonín Holý and Milena Masojídková
    Synthesis of Enantiomeric N-(2-Phosphonomethoxypropyl) Derivatives of Purine and Pyrimidine Bases. I. The Stepwise Approach
    1995, Vol. 60, Issue 7, pp. 1196–1212 [Abstract]
  • Michal Hocek, Milena Masojídková and Antonín Holý
    Synthesis of Acyclic Nucleotide Analogues Derived from 2-(Aminomethyl)adenine and 2-(Aminomethyl)hypoxanthine
    1995, Vol. 60, Issue 5, pp. 875–882 [Abstract]
  • Marcela Krečmerová, Antonín Holý and Milena Masojídková
    Synthesis of 3-(4-Pyridinyl)-, 3-(2-Chloro-4-pyridinyl)- and 3-(2-Amino-4-pyridinyl)propoxymethanephosphonic Acid
    1995, Vol. 60, Issue 4, pp. 670–680 [Abstract]
  • Marcela Krečmerová and Antonín Holý
    Preparation of Phosphonomethyl Ethers Derived from 2-Phenylethanol and Its Amino Derivatives
    1995, Vol. 60, Issue 4, pp. 659–669 [Abstract]
  • Kristina Juricová, Svatava Smrčková and Antonín Holý
    Synthesis of Base-Modified "Abbreviated" NAD Analogues
    1995, Vol. 60, Issue 2, pp. 237–250 [Abstract]
  • Dana Hocková, Milena Masojídková, Miloš Buděšínský and Antonín Holý
    Acyclic Nucleoside and Nucleotide Analogs Derived from 2-Azaadenine
    1995, Vol. 60, Issue 2, pp. 224–236 [Abstract]
  • Ivan Votruba, Antonín Holý, Hana Dvořáková, Jaroslav Günter, Dana Hocková, Hubert Hřebabecký, Tomas Cihlar and Milena Masojídková
    Synthesis of 2-Deoxy-β-D-ribonucleosides and 2,3-Dideoxy-β-D-pentofuranosides on Immobilized Bacterial Cells
    1994, Vol. 59, Issue 10, pp. 2303–2330 [Abstract]
  • Petr Alexander and Antonín Holý
    Prodrugs of Analogs of Nucleic Acid Components
    1994, Vol. 59, Issue 10, pp. 2127–2165 [Abstract]
  • Hana Dvořáková, Antonín Holý and Ivan Rosenberg
    Synthesis of Some 2'-C-Alkyl Derivatives of 9-(2-Phosphonomethoxyethyl)adenine and Related Compounds
    1994, Vol. 59, Issue 9, pp. 2069–2094 [Abstract]
  • Petr Alexander, Antonín Holý and Milena Masojídková
    Synthesis of 9-(2-Phosphinomethoxyethyl)adenine and Related Compounds
    1994, Vol. 59, Issue 8, pp. 1870–1878 [Abstract]
  • Petr Alexander, Antonín Holý and Milena Masojídková
    Preparation of 9-(2-Phosphonomethoxyethyl)adenine Esters as Potential Prodrugs
    1994, Vol. 59, Issue 8, pp. 1853–1869 [Abstract]
  • Hubert Hřebabecký and Antonín Holý
    Synthesis of Deoxy, Dideoxy and Didehydrodideoxy Analogs of 9-(4-C-Hydroxymethyl-α-L-pentofuranosyl)adenine
    1994, Vol. 59, Issue 7, pp. 1654–1664 [Abstract]
  • Hubert Hřebabecký, Jan Dočkal and Antonín Holý
    Synthesis of Deoxy, Dideoxy and Didehydrodideoxy Analogs of 9-(β-D-Hexofuranosyl)adenine
    1994, Vol. 59, Issue 6, pp. 1408–1419 [Abstract]
  • Maria Spassova, Hana Dvořáková, Antonín Holý, Miloš Buděšínský and Milena Masojídková
    Synthesis of N-(3-Azido-2-hydroxypropyl), N-(3-Phthalimido-2-hydroxypropyl) and N-(3-Amino-2-hydroxypropyl) Derivatives of Heterocyclic Bases
    1994, Vol. 59, Issue 5, pp. 1153–1174 [Abstract]
  • Hubert Hřebabecký and Antonín Holý
    Synthesis of 1-(3-Azido-2,3-dideoxy-β-D-ribo-hexofuranosyl)-, 1-(2,3-Dideoxy-β-D-erythro-hexofuranosyl)- and 1-(2,3-Dideoxy-β-D-erythro-hex-2-enofuranosyl)pyrimidine Nucleosides
    1994, Vol. 59, Issue 2, pp. 412–420 [Abstract]
  • Radek Liboska and Ivan Rosenberg
    Synthesis and antiviral activity of novel carbocyclic nucleoside and nucleotide analogs
    1993, Vol. 58, Special Issue, pp. S259–S261 [Abstract]
  • Miroslav Otmar, Ivan Rosenberg, Milena Masojídková and Antonín Holý
    [5-(9-Adeninyl)-5'-deoxy-L-pentofuranosyl]phosphonates: Conformationally restricted nucleotide analogs related to (S)-HPMPA
    1993, Vol. 58, Special Issue, pp. S256–S258 [Abstract]
  • Hubert Hřebabecký, Jan Dočkal and Antonín Holý
    Synthesis of deoxy, dideoxy and didehydrodideoxy analogues of 9-(β-D-hexofuranosyl)adenine and 9-(4-C-hydroxymethyl-α-L-pentofuranosyl)adenine
    1993, Vol. 58, Special Issue, pp. S241–S243 [Abstract]
  • Ivan Rosenberg and Radek Liboska
    Preparation of isosters of 9-[2-(phosphonomethoxy)ethyl] adenine
    1993, Vol. 58, Special Issue, pp. S94–S97 [Abstract]
  • Antonín Holý, Hana Dvořáková and Ivan Rosenberg
    Synthesis and antiviral activity of some 2'-C-alkyl derivatives of 9-(2-phosphonomethoxyethyl)adenine
    1993, Vol. 58, Special Issue, pp. S86–S90 [Abstract]
  • Miroslav Otmar, Ivan Rosenberg, Milena Masojídková and Antonín Holý
    [5-(Adenin-9-yl)-5-deoxy-L-pentofuranosyl]phosphonates - A Novel Type of Nucleotide Analogs Related to HPMPA. II. Synthesis of L-ribo and L-xylo Configurated Derivatives by Recyclization of Diethyl (5-RS)-[1,2-O-Isopropylidene-5-O-methanesulfonyl-D-pentofuranos-5-C-yl]phosphonates under Acidic Conditions
    1993, Vol. 58, Issue 9, pp. 2180–2196 [Abstract]
  • Miroslav Otmar, Ivan Rosenberg, Milena Masojídková and Antonín Holý
    [5-(Adenin-9-yl)-5-deoxypentofuranosyl]phosphonates - A Novel Type of Nucleotide Analogs Related to HPMPA. I. Derivatives with L-arabino, D-arabino, 2-Deoxy-L-erythro and 2-Deoxy-L-threo Configuration
    1993, Vol. 58, Issue 9, pp. 2159–2179 [Abstract]
  • Jiří Smrt, Luboš Arnold, Jan Svoboda, Roman Hák and Ivan Rosenberg
    Synthesis of Oligodeoxynucleotides Eliminating the Use of Acetonitrile
    1993, Vol. 58, Issue 7, pp. 1692–1698 [Abstract]
  • Hubert Hřebabecký and Antonín Holý
    Synthesis of 1-(2,3-Dideoxy-4-C-methyl-β-D-glycero-pent-2-enofuranosyl)thymine, 1-(2,3-Dideoxy-4-C-methyl-β-D-glycero-pentofuranosyl)thymine and 1-(4-C-Azidomethyl-2-deoxy-β-D-threo-pentofuranosyl)thymine
    1993, Vol. 58, Issue 7, pp. 1668–1674 [Abstract]
  • Jindřich Jindřich, Antonín Holý and Hana Dvořáková
    Synthesis of N-(3-Fluoro-2-phosphonomethoxypropyl) (FPMP) Derivatives of Heterocyclic Bases
    1993, Vol. 58, Issue 7, pp. 1645–1667 [Abstract]
  • Hana Dvořáková and Antonín Holý
    Synthesis and Biological Effects of N-(2-Phosphonomethoxyethyl) Derivatives of Deazapurine Bases
    1993, Vol. 58, Issue 6, pp. 1419–1429 [Abstract]
  • Hana Dvořáková, Antonín Holý and Petr Alexander
    Synthesis and Biological Effects of 9-(3-Hydroxy-2-phosphonomethoxypropyl) Derivatives of Deazapurine Bases
    1993, Vol. 58, Issue 6, pp. 1403–1418 [Abstract]
  • Petr Alexander and Antonín Holý
    General Method of Preparation of N-[(S)-(3-Hydroxy-2-phosphonomethoxypropyl)] Derivatives of Heterocyclic Bases
    1993, Vol. 58, Issue 5, pp. 1151–1163 [Abstract]
  • Antonín Holý
    Syntheses of Enantiomeric N-(3-Hydroxy-2-phosphonomethoxypropyl) Derivatives of Purine and Pyrimidine Bases
    1993, Vol. 58, Issue 3, pp. 649–674 [Abstract]
  • Hana Dvořáková, Antonín Holý, Ivan Votruba and Milena Masojídková
    Synthesis and Biological Effects of Acyclic Analogs of Deazapurine Nucleosides
    1993, Vol. 58, Issue 3, pp. 629–648 [Abstract]
  • Marcela Krečmerová, Hubert Hřebabecký, Milena Masojídková and Antonín Holý
    Preparation of Purine 2'-Deoxy-5'-O-phosphonomethylnucleosides and 2'-Deoxy-3'-O-phosphonomethylnucleosides
    1993, Vol. 58, Issue 2, pp. 421–434 [Abstract]
  • Hubert Hřebabecký and Antonín Holý
    Synthesis of 1-(3-Azido-2,3-dideoxy-4-C-hydroxymethyl-α-L-threo-pentofuranosyl)thymine, 1-(2,3-Dideoxy-4-C-hydroxymethyl-α-L-glycero-pentofuranosyl)thymine and 1-(2,3-Dideoxy-4-C-hydroxymethyl-α-L-glycero-pent-2-enofuranosyl)thymine
    1993, Vol. 58, Issue 2, pp. 409–420 [Abstract]
  • Pavel Kramata and Ivan Votruba
    Enzymes of Human Herpesviruses
    1992, Vol. 57, Issue 8, pp. 1577–1612 [Abstract]
  • Jindřich Jindřich, Hana Dvořáková and Antonín Holý
    Synthesis of Isomeric N-(3-Fluoro-2-hydroxypropyl) and N-(2-Fluoro-3-hydroxypropyl) Derivatives of Purine and Pyrimidine Bases
    1992, Vol. 57, Issue 7, pp. 1466–1482 [Abstract]
  • Tomas Cihlar, Ivan Votruba, Květoslava Horská, Radek Liboska, Ivan Rosenberg and Antonín Holý
    Metabolism of 1-(S)-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine (HPMPC) in Human Embryonic Lung Cells
    1992, Vol. 57, Issue 3, pp. 661–672 [Abstract]
  • Marcela Krečmerová, Hubert Hřebabecký and Antonín Holý
    5'-O-Phosphonylmethyl derivatives of 2'-deoxynucleosides
    1990, Vol. 55, Special Issue, pp. S121–S124 [Abstract]
  • Katarina Šedivá, Ivan Votruba, Antonín Holý and Ivan Rosenberg
    Purine nucleoside phosphorylase: Isolation and characterization
    1990, Vol. 55, Issue 12, pp. 2987–2999 [Abstract]
  • Marcela Krečmerová, Hubert Hřebabecký and Antonín Holý
    Synthesis of 5'-O-phosphonomethyl derivatives of pyrimidine 2'-deoxynucleosides
    1990, Vol. 55, Issue 10, pp. 2521–2536 [Abstract]
  • Květa Horská, Aleš Cvekl, Ivan Rosenberg, Antonín Holý and Karel Šebesta
    DNA-dependent RNA polymerase mediated formation of methylphosphonyl internucleotide linkage
    1990, Vol. 55, Issue 8, pp. 2100–2109 [Abstract]
  • Hubert Hřebabecký, Antonín Holý and Eric De Clercq
    Synthesis of 3'-azido-2',3'-dideoxy-6-methyluridine, 2',3'-dideoxy-6-methyluridine and 2',3'-dideoxy-2',3'-didehydro-6-methyluridine
    1990, Vol. 55, Issue 7, pp. 1801–1811 [Abstract]
  • Antonín Holý, Ivan Rosenberg and Hana Dvořáková
    Synthesis of N-(2-(2-phosphonylethoxy)ethyl) derivatives of heterocyclic bases
    1990, Vol. 55, Issue 3, pp. 809–818 [Abstract]
  • Marcela Krečmerová, Miloslav Černý, Miloš Buděšínský and Antonín Holý
    Utilization of 1,6-anhydrohexoses for the preparation of some aliphatic adenosine analogs
    1989, Vol. 54, Issue 10, pp. 2753–2766 [Abstract]
  • Antonín Holý, Ivan Rosenberg and Hana Dvořáková
    Synthesis of (3-hydroxy-2-phosphonylmethoxypropyl) derivatives of heterocyclic bases
    1989, Vol. 54, Issue 9, pp. 2470–2501 [Abstract]
  • Antonín Holý, Ivan Rosenberg and Hana Dvořáková
    Synthesis of N-(2-phosphonylmethoxyethyl) derivatives of heterocyclic bases
    1989, Vol. 54, Issue 8, pp. 2190–2210 [Abstract]
  • Aleš Cvekl, Květa Horská, Karel Šebesta, Ivan Rosenberg and Antonín Holý
    Trinucleotide AUA and UAU formation catalyzed by wheat germ RNA polymerase II
    1989, Vol. 54, Issue 3, pp. 811–818 [Abstract]
  • Antonín Holý
    Synthesis of 3-amino- and 3-azidoanalogs of 9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine (HPMPA)
    1989, Vol. 54, Issue 2, pp. 446–454 [Abstract]
  • Antonín Holý
    Branched-chain derivatives of acyclic adenosine analogs: Alkyl and hydroxymethyl derivatives of S-adenosyl-L-homocysteinase inhibitors substituted at the 2- and 3-position of the side chain
    1989, Vol. 54, Issue 1, pp. 248–265 [Abstract]
  • Ivan Rosenberg, Antonín Holý and Milena Masojídková
    Phosphonylmethoxyalkyl and phosphonylalkyl derivatives of adenine
    1988, Vol. 53, Issue 11, pp. 2753–2777 [Abstract]
  • Hana Dvořáková, Antonín Holý and Milena Masojídková
    Fluorescent analogues of acyclic inhibitors of S-adenosyl-L-homocysteine hydrolase
    1988, Vol. 53, Issue 8, pp. 1779–1794 [Abstract]
  • Antonín Holý, Masahiko Nishizawa, Ivan Rosenberg and Ivan Votruba
    The effect of phosphonylmethyl analogs of ribonucleoside 5'-diphosphates on (E. coli) polynucleotide phosphorylase catalyzed reactions
    1987, Vol. 52, Issue 12, pp. 3042–3057 [Abstract]
  • Petr Holý, Martin Bělohradský, Ivan Stibor, Juraj Koudelka, David Šaman, Jana Hodačová, Antonín Holý and Jiří Závada
    Crown and azacrown ethers with pendant adenine group
    1987, Vol. 52, Issue 12, pp. 2971–2982 [Abstract]
  • Antonín Holý and Ivan Rosenberg
    Synthesis of 9-(2-phosphonylmethoxyethyl)adenine and related compounds
    1987, Vol. 52, Issue 11, pp. 2801–2809 [Abstract]
  • Ivan Rosenberg and Antonín Holý
    Synthesis of potential prodrugs and metabolites of 9-(S)-(3-hydroxy-2-phosphonylmethoxypropyl)adenine
    1987, Vol. 52, Issue 11, pp. 2792–2800 [Abstract]
  • Antonín Holý and Ivan Rosenberg
    Synthesis of isomeric and enantiomeric O-phosphonylmethyl derivatives of 9-(2,3-dihydroxypropyl)adenine
    1987, Vol. 52, Issue 11, pp. 2775–2791 [Abstract]
  • Ivan Rosenberg and Antonín Holý
    Synthesis of phosphonylmethyl analogues of diribonucleoside monophosphates containing modified internucleotide bond
    1987, Vol. 52, Issue 10, pp. 2572–2588 [Abstract]
  • Helmut Pischel, Antonín Holý, Jiří Veselý, Günther Wagner and Dieter Cech
    Hydrophilic 1-(carboxymethyl)-5-fluorouracil amides: Preparation and cytostatic activity
    1987, Vol. 52, Issue 8, pp. 2061–2069 [Abstract]
  • Antonín Holý, Joachim König, Jiří Veselý, Dieter Cech, Ivan Votruba and Erik De Clercq
    5'-O-Alkyl-5-fluorouridines: Synthesis and biological activity
    1987, Vol. 52, Issue 6, pp. 1589–1608 [Abstract]
  • Maria K. Spassova, Antonín Holý and Milena Masojídková
    Ribonucleosides of 3-amino- and 3,5-diaminopyrazole-4-carboxylic acid and their open-chain analogues: Synthesis and reactions
    1986, Vol. 51, Issue 7, pp. 1512–1531 [Abstract]
  • Antonín Holý, Jitka Kohoutová, Aleš Merta and Ivan Votruba
    9-(Aminoalkyl)-8-hydroxyadenines: Preparation, mechanism of formation and use in affinity chromatography of S-adenosyl-L-homocysteine hydrolase
    1986, Vol. 51, Issue 2, pp. 459–477 [Abstract]
  • Milena Masojídková, Jaroslav Zajíček, Miloš Buděšínský, Ivan Rosenberg and Antonín Holý
    Conformational study on ribonucleoside O-phosphonylmethyl derivatives by 1H NMR spectroscopy
    1985, Vol. 50, Issue 8, pp. 1899–1905 [Abstract]
  • Antonín Holý and Ivan Rosenberg
    An improved synthesis of S-adenosyl-L-homocysteine and related compounds
    1985, Vol. 50, Issue 7, pp. 1514–1518 [Abstract]
  • Ivan Rosenberg and Antonín Holý
    Phosphonylmethyl analogues of ribonucleoside 2',3'-cyclic phosphates and 2'(3')-nucleotide methyl esters: Synthesis and properties
    1985, Vol. 50, Issue 7, pp. 1507–1513 [Abstract]
  • Antonín Holý, Anita Ludziša, Ivan Votruba, Kateřina Šedivá and Helmut Pischel
    Preparation of analogues of cytosine and 2-pyrimidinone nucleosides and their effect on bacterial (Escherichia coli A 19) cytidine aminohydrolase
    1985, Vol. 50, Issue 2, pp. 393–417 [Abstract]
  • Antonín Holý, Ivan Votruba and Erik De Clercq
    Structure-activity studies on open-chain analogues of nucleosides: Inhibition of S-adenosyl-L-homocysteine hydrolase and antiviral activity 2. Acid open-chain analogues
    1985, Vol. 50, Issue 1, pp. 262–279 [Abstract]
  • Antonín Holý, Ivan Votruba and Erik De Clercq
    Structure-activity studies on open-chain analogues of nucleosides: Inhibition of S-adenosyl-L-homocysteine hydrolase and antiviral activity 1. Neutral open-chain analogues
    1985, Vol. 50, Issue 1, pp. 245–261 [Abstract]
  • Helmut Pischel, Antonín Holý, Jiří Veselý and Günther Wagner
    Preparation and biological effects of N-tris(hydroxymethyl)methylaminocarbonylmethyl derivatives of heterocyclic bases
    1984, Vol. 49, Issue 11, pp. 2541–2550 [Abstract]
  • Antonín Holý
    Preparation and synthetic utilization of 3-(adenin-9-yl)-2-hydroxyalkanoic acids and their derivatives
    1984, Vol. 49, Issue 9, pp. 2148–2166 [Abstract]
  • Ladislava Šebestová, Ivan Votruba and Antonín Holý
    S-adenosine-L-homocysteine hydrolase from Nicotiana tabacum L.: Isolation and properties
    1984, Vol. 49, Issue 6, pp. 1543–1551 [Abstract]
  • Aleš Merta, Ivan Votruba, Jiří Veselý and Antonín Holý
    S-adenosyl-L-homocysteine hydrolase from mouse leukemic cells: Isolation and properties
    1983, Vol. 48, Issue 9, pp. 2701–2708 [Abstract]
  • Antonín Holý
    Preparation of isomeric 3-aminopropylamino derivatives of 9-(RS)-(2,3-dihydroxypropyl)adenine
    1983, Vol. 48, Issue 7, pp. 1910–1921 [Abstract]
  • Jiří Veselý, Ivan Rosenberg and Antonín Holý
    Donor activity of 5'-O-phosphonylmethyl analogues of ATP and GTP in the phosphorylation of uridine catalyzed by uridine kinase from mouse leukemic cells
    1983, Vol. 48, Issue 6, pp. 1783–1787 [Abstract]
  • Květa Horská, Ivan Rosenberg, Antonín Holý and Karel Šebesta
    5'-O-diphosphorylphosphonylmethylribonucleosides - A new group of DNA-dependent RNA polymerase inhibitors
    1983, Vol. 48, Issue 5, pp. 1352–1357 [Abstract]
  • Ivan Rosenberg and Antonín Holý
    Preparation of 2'(3')-O-phosphonylmethyl derivatives of ribonucleosides
    1983, Vol. 48, Issue 3, pp. 778–789 [Abstract]
  • Jiří Veselý, Ivan Rosenberg and Antonín Holý
    Inhibition by CTP and UTP analogues of uridine kinase from mouse leukemic cells
    1982, Vol. 47, Issue 12, pp. 3464–3469 [Abstract]
  • Antonín Holý and Ivan Rosenberg
    Preparation of 5'-O-phosphonylmethyl analogues of nucleoside-5'-phosphates, 5'-diphosphates and 5'-triphosphates
    1982, Vol. 47, Issue 12, pp. 3447–3463 [Abstract]
  • Antonín Holý
    Synthesis of eight stereoisomeric 5-(adenin-9-yl)-2,3,4-trihydroxypentanoic acids
    1982, Vol. 47, Issue 11, pp. 2969–2988 [Abstract]
  • Helmut Pischel, Antonín Holý, Jiří Veselý, Günther Wagner and Dieter Cech
    Synthesis and biological activity of N-substituted 5-fluorouracil-1-acetamides
    1982, Vol. 47, Issue 10, pp. 2806–2813 [Abstract]
  • Antonín Holý
    Preparation of enantiomeric and racemic 2,3,4,5-tetrahydroxypentyl derivatives of adenine, cytosine and uracil
    1982, Vol. 47, Issue 10, pp. 2786–2805 [Abstract]
  • Antonín Holý, Ivan Votruba and Erik De Clercq
    Synthesis and antiviral activity of stereoisomeric eritadenines
    1982, Vol. 47, Issue 5, pp. 1392–1407 [Abstract]
  • Antonín Holý
    Stereospecific synthesis of isomeric 4-substituted 9-(2,3-dihydroxybutyl)adenines
    1982, Vol. 47, Issue 1, pp. 173–189 [Abstract]
  • Ivan Votruba and Antonín Holý
    Eritadenines - Novel type of potent inhibitors of S-adenosyl-L-homocysteine hydrolase
    1982, Vol. 47, Issue 1, pp. 167–172 [Abstract]
  • Antonín Holý
    Preparation of aliphatic analogues of S-adenosyl-L-homocysteine and related compounds
    1981, Vol. 46, Issue 12, pp. 3134–3144 [Abstract]
  • Helmut Pischel, Antonín Holý and Günther Wagner
    Preparation of conjugates of uridine with proteins by the imido ester condensation method
    1981, Vol. 46, Issue 4, pp. 933–940 [Abstract]
  • Svetlana Pristašová, Marta Rosenbergová and Antonín Holý
    Decyclizing phosphodiesterases associated with plasma membranes of the chick chorioalantois
    1981, Vol. 46, Issue 2, pp. 520–524 [Abstract]
  • Beatrice Schwarz, Dieter Cech, Antonín Holý and Jan Škoda
    Preparation, antibacterial effects and enzymatic degradation of 5-fluorouracil nucleosides
    1980, Vol. 45, Issue 11, pp. 3217–3230 [Abstract]
  • Ivan Votruba and Antonín Holý
    Inhibition of S-adenosyl-L-homocysteine hydrolase by the aliphatic nucleoside analogue - 9-(S)-(2,3-dihydroxypropyl)adenine
    1980, Vol. 45, Issue 11, pp. 3039–3044 [Abstract]
  • Pavol Kois, Ivan Rosenberg and Antonín Holý
    Affinity chromatography of guanyloribonuclease from streptomyces aureofaciens
    1980, Vol. 45, Issue 10, pp. 2839–2846 [Abstract]
  • Pavol Kois and Antonín Holý
    Preparation of derivatives of inosine 5'-phosphorothioate for use in affinity chromatography
    1980, Vol. 45, Issue 10, pp. 2830–2838 [Abstract]
  • Antonín Holý and Pavol Kois
    Synthesis of 2'(3')-phosphates and 2'(3')-phosphorothioates of 5'-O-carboxymethylinosine and related compounds
    1980, Vol. 45, Issue 10, pp. 2817–2829 [Abstract]
  • Antonín Holý and Erik De Clercq
    Preparation, spectral properties and biological activities of 5-bromo-6-methyl-2'-deoxyuridine and 5-iodo-6-methyl-2'-deoxyuridine
    1980, Vol. 45, Issue 8, pp. 2364–2370 [Abstract]
  • Antonina P. Kavunenko and Antonín Holý
    Ribonuclease a catalyzed preparative synthesis of dinucleoside monophosphates containing uridine analogues
    1980, Vol. 45, Issue 2, pp. 611–616 [Abstract]
  • Helmut Pischel, Antonín Holý and Günther Wagner
    Synthesis of conjugates of 5'-O-carboxymethyl-5-halogeno-2'-deoxyuridines and 5'-O-carboxymethyl-5-halogenouridines with proteins
    1980, Vol. 45, Issue 2, pp. 606–610 [Abstract]
  • Ivan Rosenberg and Antonín Holý
    Nucleolytic enzymes of rape seedlings II. Unspecific acid phosphomonoester hydrolase
    1979, Vol. 44, Issue 11, pp. 3327–3340 [Abstract]
  • Helmut Pischel, Antonín Holý and Günther Wagner
    Synthesis of conjugates of 1-(carboxymethyl)cytosine and 1-(5-O-carboxymethyl-β-D-arabinofuranosyl)cytosine with proteins
    1979, Vol. 44, Issue 10, pp. 3023–3032 [Abstract]
  • Antonín Holý
    Preparation of 9-(β-D-ribofuranosyl)-2-hydroxypurine
    1979, Vol. 44, Issue 9, pp. 2846–2853 [Abstract]
  • Antonín Holý and Miroslav Vaněček
    The synthesis and the pharmacological properties of enantiomeric derivatives of 7-(2,3-dihydroxypropyl)theophylline
    1979, Vol. 44, Issue 8, pp. 2550–2555 [Abstract]
  • Antonín Holý
    Acid-catalyzed migration of N4-acyl groups in cytosine derivatives
    1979, Vol. 44, Issue 6, pp. 1819–1827 [Abstract]
  • Helmut Pischel, Antonín Holý and Günther Wagner
    Synthesis of conjugates of 5-halouracils with proteins using activated esters
    1979, Vol. 44, Issue 5, pp. 1634–1641 [Abstract]
  • Antonín Holý and Ivan Rosenberg
    New pyrimidine (uridine) specific cyclizing 2'-ribonucleotidyltransferase and nonspecific decyclizing 2',3'-phosphodiesterase
    1979, Vol. 44, Issue 3, pp. 957–975 [Abstract]
  • Valentina I. Gulyaeva and Antonín Holý
    The effect of acceptor modification upon the synthesis of dinucleoside phosphates catalyzed by non-specific ribonucleases of Penicillium claviforme
    1979, Vol. 44, Issue 2, pp. 613–625 [Abstract]
  • Antonín Holý
    Synthesis of racemic and optically active erythro- and threo-9-(2,3,4-trihydroxybutyl)adenines and related compounds
    1979, Vol. 44, Issue 2, pp. 593–612 [Abstract]
  • Antonín Holý
    Synthesis of new mono- and disubstituted hydroxyalkyl and aminoalkyl derivatives of heterocyclic bases
    1978, Vol. 43, Issue 12, pp. 3444–3465 [Abstract]
  • Jiřina Černá, Antonín Holý and Ivan Rychlík
    The stimulation of ribosomal peptidyl transferase by cytosine and its derivatives
    1978, Vol. 43, Issue 12, pp. 3279–3291 [Abstract]
  • Antonín Holý
    Synthesis of some 2,3-dihydroxypropyl derivatives of purine bases
    1978, Vol. 43, Issue 11, pp. 3103–3117 [Abstract]
  • Magdaléna Rosinová, Antonín Holý and Eva Zelinková
    Substrate specificity of adenosine aminohydrolase from Streptomyces aureofaciens
    1978, Vol. 43, Issue 9, pp. 2330–2340 [Abstract]
  • Alois Čihák and Antonín Holý
    Distribution and metabolic transformation of 9-(S)-(2,3-dihydroxypropyl)adenine, an effective virostatic agent, in mice
    1978, Vol. 43, Issue 8, pp. 2082–2088 [Abstract]
  • Antonín Holý
    Synthesis of N-(2,3-dihydroxypropyl) derivatives of heterocyclic bases
    1978, Vol. 43, Issue 8, pp. 2054–2061 [Abstract]