Collect. Czech. Chem. Commun. 2011, 76, 1487-1527
https://doi.org/10.1135/cccc2011176
Published online 2011-12-16 14:15:30

6-Alkynylpurines bearing electronacceptor substituents: Preparation, reactivity in cycloaddition reactions and cytostatic activity

Martin Křováčeka, Hana Dvořákováb, Ivan Votrubac, Ivana Císařovád and Dalimil Dvořáka,*

a Department of Organic Chemistry, Institute of Chemical Technology, Prague, Technická 5, 166 28 Prague 6, Czech Republic
b Laboratory of NMR Spectroscopy, Institute of Chemical Technology, Prague, Technická 5, 166 28 Prague 6, Czech Republic
c Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i., Flemingovo nám. 2, 166 10 Prague 6, Czech Republic
d Department of Inorganic Chemistry, Charles University in Prague, Hlavova 2030, 128 40 Prague 2, Czech Republic

Individual author index pages


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    4,4'-Bipyridine-2,2',6,6'-tetracarboxamide. Synthesis and Self-Assembling Properties of the Free Base and the 1 : 1 Silver(I) Triflate Complex
    2002, Vol. 67, Issue 8, pp. 1236–1246 [Abstract]
  • Michal Hocek*, Irena G. Stará, Ivo Starý and Hana Dvořáková
    Covalent Analogues of DNA Base-Pairs and Triplets IV. Synthesis of Trisubstituted Benzenes Bearing Purine and/or Pyrimidine Rings by Cyclotrimerization of 6-Ethynylpurines and/or 5-Ethynyl-1,3-dimethyluracil
    2002, Vol. 67, Issue 8, pp. 1223–1235 [Abstract]
  • Bohumír Grüner*, Ivana Císařová, Josef Čáslavský, Bernard Bonnetot and David Cornu
    Synthesis of 12-Hydroxy and 12-Dioxane Derivatives of the closo-1-Carbadodecaborate(1-) Ion. Variations on the Plešek's Cobalt Bis(dicarbollide) Pattern
    2002, Vol. 67, Issue 7, pp. 953–964 [Abstract]
  • Jaromír Plešek*, Ivana Císařová and Jaroslav Bačkovský
    Cobalt Bis(1,2-dicarbollide) Ion with a Disulfur Bridge Between B(8) and B(8'). X-Ray Structure, Absolute Configuration of One Enantiomer, and Implications
    2002, Vol. 67, Issue 5, pp. 569–576 [Abstract]
  • Hana Petříčková, Jan Čejka, Michal Hušák, Bohumil Kratochvíl, Ivana Císařová, Alexandr Jegorov* and Ladislav Cvak
    Structure Types of Dihydroergotoxine Mesylates
    2002, Vol. 67, Issue 4, pp. 490–501 [Abstract]
  • Michal Hušák, Bohumil Kratochvíl, Ivana Císařová, Ladislav Cvak, Alexandr Jegorov* and Stanislav Böhm
    Crystal Forms of Semisynthetic Ergot Alkaloid Terguride
    2002, Vol. 67, Issue 4, pp. 479–489 [Abstract]
  • Michal Hocek*, Antonín Holý and Hana Dvořáková
    Cytostatic 6-Arylpurine Nucleosides IV. Synthesis of 2-Substituted 6-Phenylpurine Ribonucleosides
    2002, Vol. 67, Issue 3, pp. 325–335 [Abstract]
  • Gabriel Birkuš, Ivan Votruba*, Miroslav Otmar and Antonín Holý
    Interactions of 1-[(S)-3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine (Cidofovir) Diphosphate with DNA Polymerases α, δ and ε*
    2001, Vol. 66, Issue 11, pp. 1698–1706 [Abstract]
  • Antonín Holý*, Ivan Votruba, Eva Tloušťová and Milena Masojídková
    Synthesis and Cytostatic Activity of N-[2-(Phosphonomethoxy)alkyl] Derivatives of N6-Substituted Adenines, 2,6-Diaminopurines and Related Compounds
    2001, Vol. 66, Issue 10, pp. 1545–1592 [Abstract]
  • Jaroslav Zemánek, Lenka Fröhlichová, Pavel Šindelář, Petr Štěpnička, Ivana Císařová, Vojtech Varga, Michal Horáček and Karel Mach*
    Synthesis of Trichloro(η5-alkenyltetramethylcyclopentadienyl)titanium(IV) Complexes and Their Activity in Styrene Polymerization
    2001, Vol. 66, Issue 9, pp. 1359–1374 [Abstract]
  • Petr Holý, Jaroslav Podlaha, Ivana Císařová and Jiří Závada*
    Self-Assembly of 1,1'-Biphenyl-2,2',6,6'-tetracarboxamides. Effect of Substitution at the Amidic Nitrogen
    2001, Vol. 66, Issue 6, pp. 947–958 [Abstract]
  • Petr Holý, Jiří Závada*, Josef Zezula, Ivana Císařová and Jaroslav Podlaha
    Formation of Infinite Grids with Chiral Square Compartments by Self-Assembly of Achiral 1,1'-Biphenyl-2,2',6,6'-tetracarboxylic Acids. Effect of 4,4'-Substitution on the Grid Stacking
    2001, Vol. 66, Issue 5, pp. 820–832 [Abstract]
  • Jaroslav Zemánek, Petr Štěpnička, Karla Fejfarová, Róbert Gyepes, Ivana Císařová, Michal Horáček, Jiří Kubišta, Vojtech Varga and Karel Mach*
    Synthesis and Crystal Structures of Dimethylsilylene-Bridged (Amidocyclopentadienyl)dichlorotitanium(IV) Complexes with Various Substituents on the Cyclopentadienyl Ligand
    2001, Vol. 66, Issue 4, pp. 605–620 [Abstract]
  • Dušan Drahoňovský, Ivana Císařová, Petr Štěpnička, Hana Dvořáková, Petr Maloň and Dalimil Dvořák*
    An Alternative Approach to Chiral 2-[1'-(Diphenylphosphanyl)ferrocenyl]-4,5-dihydrooxazoles
    2001, Vol. 66, Issue 4, pp. 588–604 [Abstract]
  • Miroslav Otmar*, Milena Masojídková, Ivan Votruba and Antonín Holý
    An Alternative Synthesis of HPMPC and HPMPA Diphosphoryl Derivatives
    2001, Vol. 66, Issue 3, pp. 500–506 [Abstract]
  • Michal Hocek*, Antonín Holý, Ivan Votruba and Hana Dvořáková
    Cytostatic 6-Arylpurine Nucleosides III. Synthesis and Structure-Activity Relationship Study in Cytostatic Activity of 6-Aryl-, 6-Hetaryl- and 6-Benzylpurine Ribonucleosides
    2001, Vol. 66, Issue 3, pp. 483–499 [Abstract]
  • Jan Kotek, Pavel Vojtíšek, Ivana Císařová, Petr Hermann* and Ivan Lukeš
    Unusual cis/trans Isomerism in Octahedral Nickel(II) Complexes with 1,4,8,11-Tetraazacyclotetradecane-1,8-bis(methylphosphonic Acid) as a Ligand
    2001, Vol. 66, Issue 2, pp. 363–381 [Abstract]
  • Radek Cibulka*, Ivana Císařová, Jan Ondráček, František Liška and Jiří Ludvík
    Electrochemical Reductions of Ni2+, Cu2+ and Zn2+ Complexes of Azinyl Methyl Ketoximes on Mercury
    2001, Vol. 66, Issue 1, pp. 170–184 [Abstract]
  • Michal Hušák, Bohumil Kratochvíl, Ivana Císařová and Alexandr Jegorov*
    Crystal Structures of Two New Cyclosporin Clathrates
    2000, Vol. 65, Issue 12, pp. 1950–1958 [Abstract]
  • Lenka Lukešová, Jiří Ludvík, Ivana Císařová and Petr Štěpnička*
    Group 6 Metal Mixed Carbonyl Complexes with a Carboxyferrocenylphosphane
    2000, Vol. 65, Issue 12, pp. 1897–1910 [Abstract]
  • Michal Hocek*, Antonín Holý, Ivan Votruba and Hana Dvořáková
    Cytostatic 6-Arylpurine Nucleosides II. Synthesis of Sugar-Modified Derivatives: 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-, 9-(5-Deoxy-β-D-ribofuranosyl)- and 9-(2,3-Dihydroxypropyl)-6-phenylpurines
    2000, Vol. 65, Issue 11, pp. 1683–1697 [Abstract]
  • Romana Krejčová, Květoslava Horská, Ivan Votruba* and Antonín Holý
    Phosphorylation of Purine (Phosphonomethoxy)alkyl Derivatives by Mitochondrial AMP Kinase (AK2 Type) from L1210 Cells
    2000, Vol. 65, Issue 10, pp. 1653–1668 [Abstract]
  • Jaroslav Podlaha, Ivana Císařová, Daniel Alexander, Petr Holý, Tomáš Kraus and Jiří Závada*
    Topological Correspondence Between Crystal Structure of 2,4,6-Trimethylbenzene-1,3,5-tris(methanaminium) 2,4,6-Trimethylbenzene-1,3,5-triacetate and Cesium Chloride
    2000, Vol. 65, Issue 10, pp. 1587–1596 [Abstract]
  • Jan Kotek, Pavel Vojtíšek, Ivana Císařová, Petr Hermann*, Petr Jurečka, Jan Rohovec and Ivan Lukeš
    Bis(methylphosphonic Acid) Derivatives of 1,4,8,11-Tetraazacyclotetradecane (Cyclam). Synthesis, Crystal and Molecular Structures, and Solution Properties
    2000, Vol. 65, Issue 8, pp. 1289–1316 [Abstract]
  • Jaroslav Podlaha, Ivana Císařová*, Ludmila Soukupová and Jan Schraml
    Molecular and Crystal Structure of Benzohydroxamic Acid and Its Ring-Substituted Derivatives
    2000, Vol. 65, Issue 8, pp. 1273–1288 [Abstract]
  • Róbert Gyepes, Ivana Císařová, Michal Horáček, Jiří Čejka, Lidmila Petrusová and Karel Mach*
    Crystal Structures of Unusual Titanocene By-products from Attempted Dimerization of Terminal Alkynes
    2000, Vol. 65, Issue 8, pp. 1248–1261 [Abstract]
  • Martina Havelková, Martin Studenovský and Dalimil Dvořák*
    N1-Substituted Hypoxanthine Derivatives from the Reaction of 6-Halopurines with Michael Acceptors Under the Conditions of Heck Reaction
    2000, Vol. 65, Issue 5, pp. 797–804 [Abstract]
  • Daniel Alexander, Stanislav Böhm, Ivana Císařová, Petr Holý, Jaroslav Podlaha, Miroslav Šlouf and Jiří Závada*
    Sterically Crowded Hexaalkyl Benzene-1,2,3,4,5,6-hexakis[α-(alkoxycarbonyl)propanoates]. Synthesis and Conformation Analysis
    2000, Vol. 65, Issue 5, pp. 673–694 [Abstract]
  • Robert Klvaňa, Radek Pohl, Jan Pawlas, Jan Čejka, Hana Dvořáková, Richard Hrabal, Stanislav Böhm*, Bohumil Kratochvíl and Josef Kuthan
    Sterically Crowded Heterocycles. XII. Atropisomerism of (1-Aryl-3,5-diphenyl-1H-pyrrol-2-yl)(phenyl)methanones
    2000, Vol. 65, Issue 5, pp. 651–666 [Abstract]
  • Miroslav Havránek and Dalimil Dvořák*
    3-(Tributylstannyl)allyl Alcohols: Useful Building Blocks for Solid-Phase Synthesis of Skipped Dienes and Trienes
    2000, Vol. 65, Issue 3, pp. 434–454 [Abstract]
  • Ivana Císařová, Jaroslav Podlaha, Stanislav Böhm and Otto Exner*
    Steric Effects and Steric Inhibition of Resonance in Benzene Derivatives: 2,3-Dimethylbenzoic Acid
    2000, Vol. 65, Issue 2, pp. 216–226 [Abstract]
  • Romana Krejčová, Květoslava Horská, Ivan Votruba* and Antonín Holý
    Isoenzymes of GMP Kinase from L1210 Cells: Isolation and Characterization
    1999, Vol. 64, Issue 3, pp. 559–570 [Abstract]
  • Pavel Pihera, Hana Dvořáková and Jiří Svoboda*
    Diels-Alder Reactions of Vinyl Derivatives of [1]Benzothieno[3,2-b]furan
    1999, Vol. 64, Issue 2, pp. 389–407 [Abstract]
  • Antonín Holý*, Miloš Buděšínský, Jaroslav Podlaha and Ivana Císařová
    Synthesis of Quaternary 1-[2-(Phosphonomethoxy)ethyl] Derivatives of 2,4-Diaminopyrimidine and Related Acyclic Nucleotide Analogs
    1999, Vol. 64, Issue 2, pp. 242–256 [Abstract]
  • Petr Suchý, Dalimil Dvořák* and Martina Havelková
    Unexpected Course of the Reaction of 1,3-Bis(dimethylamino)trimethinium Perchlorate with 3-Substituted Prop-2-ynals Leading to 1-Aryl-2,4,6-triformylbenzenes
    1999, Vol. 64, Issue 1, pp. 119–129 [Abstract]
  • Hana Dvořáková, Dalimil Dvořák and Antonín Holý
    Synthesis of Acyclic Nucleotide Analogues Derived from 6-(sec- or tert-Alkyl)purines via Coupling of 6-Chloropurine Derivatives with Organocuprates
    1998, Vol. 63, Issue 12, pp. 2065–2074 [Abstract]
  • Gabriel Birkuš, Pavel Kramata, Ivan Votruba, Berta Otová, Miroslav Otmar and Antonín Holý
    Nonproteolyzed Form of DNA-Polymerase ε from T-Cell Spontaneous Lymphoma of Sprague-Dawley Inbred Rat: Isolation and Characterization
    1998, Vol. 63, Issue 5, pp. 723–731 [Abstract]
  • Miloš Tichý, Luděk Ridvan, Miloš Buděšínský, Jiří Závada, Jaroslav Podlaha and Ivana Císařová
    Axially Chiral Bis(α-amino Acid)s and Their Deamino Analogues. Synthesis and Configurational Assignment
    1998, Vol. 63, Issue 2, pp. 211–221 [Abstract]
  • Petr Štěpnička, Ivana Císařová, Jan Sedláček, Jiří Vohlídal and Miroslav Polášek
    Synthesis of Triferrocenylbenzenes by Tantalum(V)-Catalyzed Cyclotrimerization of Ethynylferrocene. The Crystal Structure of 1,3,5-Triferrocenylbenzene
    1997, Vol. 62, Issue 10, pp. 1577–1584 [Abstract]
  • Lenka Olšanská, Tomas Cihlar, Ivan Votruba* and Antonín Holý
    Transport of Adefovir (PMEA) in Human T-Lymphoblastoid Cells
    1997, Vol. 62, Issue 5, pp. 821–828 [Abstract]
  • Jaromír Plešek, Stanislav Heřmánek, Andreas Franken, Ivana Císařová and Christiane Nachtigal
    Dimethyl Sulfate Induced Nucleophilic Substitution of the [Bis(1,2-dicarbollido)-3-cobalt(1-)]ate Ion. Syntheses, Properties and Structures of Its 8,8'-μ-Sulfato, 8-Phenyland 8-Dioxane Derivatives
    1997, Vol. 62, Issue 1, pp. 47–56 [Abstract]
  • Pavel Kramata, Gabriel Birkuš, Miroslav Otmar, Ivan Votruba and Antonín Holý
    Structural features of acyclic nucleotide analogs conferring inhibitory effects on cellular replicative DNA polymerases
    1996, Vol. 61, Special Issue, pp. S188–S191 [Abstract]
  • Antonín Holý, Zdeněk Zídek and Ivan Votruba
    Inhibition of murine lymphocyte proliferation by N6-substituted acyclic purine nucleoside phosphonates
    1996, Vol. 61, Special Issue, pp. S182–S187 [Abstract]
  • Romana Krejčová, Květoslava Horská, Ivan Votruba and Antonín Holý
    Phosphorylation of phosphonomethoxyalkylguanines by GMP-kinase isoenzymes
    1996, Vol. 61, Special Issue, pp. S134–S136 [Abstract]
  • Roman Wágner, Dalimil Dvořák and Antonín Holý
    New application of the Stille coupling in the synthesis of 5-substituted uracils
    1996, Vol. 61, Special Issue, pp. S118–S119 [Abstract]
  • Zdeněk Arnold, Dalimil Dvořák and Miroslav Havránek
    Convenient Preparation of 1,3-Bis(dimethylamino)trimethinium Perchlorate, Tetrafluoroborate and Hexafluorophosphate
    1996, Vol. 61, Issue 11, pp. 1637–1641 [Abstract]
  • Petr Štěpnička and Ivana Císařová
    Crystal Structure of Dibromo(η4-1,5-cyclooctadiene)palladium(II)
    1996, Vol. 61, Issue 9, pp. 1335–1341 [Abstract]
  • Pavel Vojtíšek and Ivana Císařová
    Complexes of Tris(N-piperidinomethyl)phosphine Oxide with Zinc and Cadmium
    1996, Vol. 61, Issue 9, pp. 1321–1334 [Abstract]
  • Michal Horáček, Róbert Gyepes, Ivana Císařová, Miroslav Polášek, Vojtech Varga and Karel Mach
    Syntheses and Crystal Structures of Bis[(trimethylsilyl)tetramethylcyclopentadienyl]titanium Dichloride and Monochloride
    1996, Vol. 61, Issue 9, pp. 1307–1320 [Abstract]
  • Zdeněk Mička, Lucie Prokopová, Ivana Císařová and David Havlíček
    Crystal Structure, Thermoanalytical Properties and Infrared Spectra of Double Magnesium Selenates
    1996, Vol. 61, Issue 9, pp. 1295–1306 [Abstract]
  • Jiří Vohlídal, Jaromír Plešek, Jan Sedláček, Ivana Císařová, Pavel Matějka and Stanislav Heřmánek
    Cobaltacarboranylacetylene 8,8'-(μ-CHC-CH2S)-(1,2-C2B9H10)2-3-Co(III): Synthesis, Characterization and Polymerization of New Substituted Acetylene
    1996, Vol. 61, Issue 6, pp. 877–887 [Abstract]
  • Václav Všetečka, Ivana Císařová and Jaroslav Podlaha
    Conformation of Methylsulfonyl Group: A Comparison of the Data for 2-Chlorophenyl Methyl Sulfone in Solution and in Crystal
    1996, Vol. 61, Issue 5, pp. 733–741 [Abstract]
  • Jaroslav Podlaha, Ivana Císařová, Martin Bělohradský and Jiří Závada
    Crystal and Molecular Structure of cis-2,2',3',2"-Tetraacetoxy-1,1':4',1"-ternaphthyl
    1996, Vol. 61, Issue 5, pp. 726–732 [Abstract]
  • Roman Řeřicha, Ivana Císařová and Jaroslav Podlaha
    Crystal and Molecular Structure of Lithium Benzohydroxamate-Benzohydroxamic Acid (1 : 1) Adduct
    1996, Vol. 61, Issue 1, pp. 139–146 [Abstract]
  • Pavel Kramata, Jaroslav Černý, Gabriel Birkuš, Ivan Votruba, Berta Otová and Antonín Holý
    DNA-Polymerases α, δ and ε from T-Cell Spontaneous Lymphoblastic Leukemia of Sprague-Dawley Inbred Rat: Isolation and Characterization
    1995, Vol. 60, Issue 9, pp. 1555–1572 [Abstract]
  • Antonín Holý, Hana Dvořáková and Milena Masojídková
    Synthesis of Enantiomeric N-(2-Phosphonomethoxypropyl) Derivatives of Purine and Pyrimidine Bases. II. The Synthon Approach
    1995, Vol. 60, Issue 8, pp. 1390–1409 [Abstract]
  • Ivana Císařová, Jana Podlahová and Jaroslav Podlaha
    Crystal Structure of the Adduct Hexahydroxotelluric Acid-Disodium Ethylenediaminetetraacetate-Water (1/1/2)
    1995, Vol. 60, Issue 5, pp. 820–828 [Abstract]
  • Ivan Votruba, Antonín Holý, Hana Dvořáková, Jaroslav Günter, Dana Hocková, Hubert Hřebabecký, Tomas Cihlar and Milena Masojídková
    Synthesis of 2-Deoxy-β-D-ribonucleosides and 2,3-Dideoxy-β-D-pentofuranosides on Immobilized Bacterial Cells
    1994, Vol. 59, Issue 10, pp. 2303–2330 [Abstract]
  • Hana Dvořáková, Antonín Holý and Ivan Rosenberg
    Synthesis of Some 2'-C-Alkyl Derivatives of 9-(2-Phosphonomethoxyethyl)adenine and Related Compounds
    1994, Vol. 59, Issue 9, pp. 2069–2094 [Abstract]
  • Maria Spassova, Hana Dvořáková, Antonín Holý, Miloš Buděšínský and Milena Masojídková
    Synthesis of N-(3-Azido-2-hydroxypropyl), N-(3-Phthalimido-2-hydroxypropyl) and N-(3-Amino-2-hydroxypropyl) Derivatives of Heterocyclic Bases
    1994, Vol. 59, Issue 5, pp. 1153–1174 [Abstract]
  • Antonín Holý, Hana Dvořáková and Ivan Rosenberg
    Synthesis and antiviral activity of some 2'-C-alkyl derivatives of 9-(2-phosphonomethoxyethyl)adenine
    1993, Vol. 58, Special Issue, pp. S86–S90 [Abstract]
  • Jindřich Jindřich, Antonín Holý and Hana Dvořáková
    Synthesis of N-(3-Fluoro-2-phosphonomethoxypropyl) (FPMP) Derivatives of Heterocyclic Bases
    1993, Vol. 58, Issue 7, pp. 1645–1667 [Abstract]
  • Hana Dvořáková and Antonín Holý
    Synthesis and Biological Effects of N-(2-Phosphonomethoxyethyl) Derivatives of Deazapurine Bases
    1993, Vol. 58, Issue 6, pp. 1419–1429 [Abstract]
  • Hana Dvořáková, Antonín Holý and Petr Alexander
    Synthesis and Biological Effects of 9-(3-Hydroxy-2-phosphonomethoxypropyl) Derivatives of Deazapurine Bases
    1993, Vol. 58, Issue 6, pp. 1403–1418 [Abstract]
  • Hana Dvořáková, Antonín Holý, Ivan Votruba and Milena Masojídková
    Synthesis and Biological Effects of Acyclic Analogs of Deazapurine Nucleosides
    1993, Vol. 58, Issue 3, pp. 629–648 [Abstract]
  • Dalimil Dvořák, David Šaman, Zdeněk Arnold, Ivana Císařová and Václav Petříček
    Cycloaddition Reactions of Arylmethylenemalonaldehydes with Olefins
    1992, Vol. 57, Issue 11, pp. 2337–2358 [Abstract]
  • Pavel Kramata and Ivan Votruba
    Enzymes of Human Herpesviruses
    1992, Vol. 57, Issue 8, pp. 1577–1612 [Abstract]
  • Jindřich Jindřich, Hana Dvořáková and Antonín Holý
    Synthesis of Isomeric N-(3-Fluoro-2-hydroxypropyl) and N-(2-Fluoro-3-hydroxypropyl) Derivatives of Purine and Pyrimidine Bases
    1992, Vol. 57, Issue 7, pp. 1466–1482 [Abstract]
  • Tomas Cihlar, Ivan Votruba, Květoslava Horská, Radek Liboska, Ivan Rosenberg and Antonín Holý
    Metabolism of 1-(S)-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine (HPMPC) in Human Embryonic Lung Cells
    1992, Vol. 57, Issue 3, pp. 661–672 [Abstract]
  • Katarina Šedivá, Ivan Votruba, Antonín Holý and Ivan Rosenberg
    Purine nucleoside phosphorylase: Isolation and characterization
    1990, Vol. 55, Issue 12, pp. 2987–2999 [Abstract]
  • Ladislav Lešetický, Stanislav Smrček, Vladimír Sváta, Jana Podlahová, Jaroslav Podlaha and Ivana Císařová
    The synthesis and X-ray structure of 3,7-diiododibenzosuberone. Synthesis of 3,7-diiodoamitriptyline
    1990, Vol. 55, Issue 11, pp. 2677–2684 [Abstract]
  • Antonín Holý, Ivan Rosenberg and Hana Dvořáková
    Synthesis of N-(2-(2-phosphonylethoxy)ethyl) derivatives of heterocyclic bases
    1990, Vol. 55, Issue 3, pp. 809–818 [Abstract]
  • Antonín Holý, Ivan Rosenberg and Hana Dvořáková
    Synthesis of (3-hydroxy-2-phosphonylmethoxypropyl) derivatives of heterocyclic bases
    1989, Vol. 54, Issue 9, pp. 2470–2501 [Abstract]
  • Antonín Holý, Ivan Rosenberg and Hana Dvořáková
    Synthesis of N-(2-phosphonylmethoxyethyl) derivatives of heterocyclic bases
    1989, Vol. 54, Issue 8, pp. 2190–2210 [Abstract]
  • Pavel Kočovský and Dalimil Dvořák
    Transition-metal catalysis in Michael addition of β-dicarbonyls: Tuning of the reaction conditions
    1988, Vol. 53, Issue 11, pp. 2667–2674 [Abstract]
  • Hana Dvořáková, Antonín Holý and Milena Masojídková
    Fluorescent analogues of acyclic inhibitors of S-adenosyl-L-homocysteine hydrolase
    1988, Vol. 53, Issue 8, pp. 1779–1794 [Abstract]
  • Antonín Holý, Masahiko Nishizawa, Ivan Rosenberg and Ivan Votruba
    The effect of phosphonylmethyl analogs of ribonucleoside 5'-diphosphates on (E. coli) polynucleotide phosphorylase catalyzed reactions
    1987, Vol. 52, Issue 12, pp. 3042–3057 [Abstract]
  • Dalimil Dvořák, David Šaman, Miloš Buděšínský and Zdeněk Arnold
    Arbuzov rearrangement in the reaction of arylmethylenemalonaldehydes with trimethyl phosphite: Formation of 2-(α-dimethoxyphosphonylbenzyl)-3-methoxyacroleins
    1987, Vol. 52, Issue 12, pp. 2926–2935 [Abstract]
  • Dalimil Dvořák and Zdeněk Arnold
    Reaction of arylmethylenemalonaldehydes with some nucleophiles
    1987, Vol. 52, Issue 11, pp. 2699–2709 [Abstract]
  • Dalimil Dvořák, David Šaman, Jana Hodačová, Vladimír Král and Zdeněk Arnold
    Michael reaction of methylenemalonaldehydes: Synthetic approach to 4H-pyran-5-carboxaldehydes and 2-amino-4H-pyran-5-carboxaldehydes
    1987, Vol. 52, Issue 11, pp. 2687–2698 [Abstract]
  • Jiří Brynda, Bohumil Kratochvíl and Ivana Císařová
    The determination of crystal structure of chromium(II) phosphite dihydrate, CrHPO3 2 H2O
    1987, Vol. 52, Issue 7, pp. 1742–1747 [Abstract]
  • Antonín Holý, Joachim König, Jiří Veselý, Dieter Cech, Ivan Votruba and Erik De Clercq
    5'-O-Alkyl-5-fluorouridines: Synthesis and biological activity
    1987, Vol. 52, Issue 6, pp. 1589–1608 [Abstract]
  • Antonín Holý, Jitka Kohoutová, Aleš Merta and Ivan Votruba
    9-(Aminoalkyl)-8-hydroxyadenines: Preparation, mechanism of formation and use in affinity chromatography of S-adenosyl-L-homocysteine hydrolase
    1986, Vol. 51, Issue 2, pp. 459–477 [Abstract]
  • Ludmila A. Yanovskaya, Galya V. Kryshtal, Dalimil Dvořák, Vladimír Král and Zdeněk Arnold
    Substituted methylenemalonaldehydes: Condensation of dialdehydes with 1,3-bis(dimethylamino)trimethinium perchlorate
    1985, Vol. 50, Issue 10, pp. 2270–2274 [Abstract]
  • Zdeněk Arnold and Dalimil Dvořák
    Benzylidenemalonaldehydes: Synthesis of 4-aryl-2-dimethylamino-4H-1,3-oxazine-5-carboxaldehyde
    1985, Vol. 50, Issue 10, pp. 2265–2269 [Abstract]
  • Dalimil Dvořák, Miloš Buděšínský, David Šaman and Zdeněk Arnold
    Benzylidenemalonaldehydes: A redox reaction during the attempted cycloaddition on nitrosobenzene
    1985, Vol. 50, Issue 10, pp. 2260–2264 [Abstract]
  • Ludmila A. Yanovskaya, Galya V. Kryshtal, Dalimil Dvořák, Vladimír Král and Zdeněk Arnold
    Synthesis of polyenylidenemalonaldehydes
    1985, Vol. 50, Issue 6, pp. 1300–1304 [Abstract]
  • Antonín Holý, Anita Ludziša, Ivan Votruba, Kateřina Šedivá and Helmut Pischel
    Preparation of analogues of cytosine and 2-pyrimidinone nucleosides and their effect on bacterial (Escherichia coli A 19) cytidine aminohydrolase
    1985, Vol. 50, Issue 2, pp. 393–417 [Abstract]
  • Antonín Holý, Ivan Votruba and Erik De Clercq
    Structure-activity studies on open-chain analogues of nucleosides: Inhibition of S-adenosyl-L-homocysteine hydrolase and antiviral activity 2. Acid open-chain analogues
    1985, Vol. 50, Issue 1, pp. 262–279 [Abstract]
  • Antonín Holý, Ivan Votruba and Erik De Clercq
    Structure-activity studies on open-chain analogues of nucleosides: Inhibition of S-adenosyl-L-homocysteine hydrolase and antiviral activity 1. Neutral open-chain analogues
    1985, Vol. 50, Issue 1, pp. 245–261 [Abstract]
  • Zdeněk Arnold, Dalimil Dvořák and Vladimír Král
    Vinylogues and heterocyclic analogues of benzylidenemalonaldehydes
    1984, Vol. 49, Issue 11, pp. 2613–2619 [Abstract]
  • Zdeněk Arnold, Vladimír Král and Dalimil Dvořák
    Synthesis of benzylidenemalonaldehydes
    1984, Vol. 49, Issue 11, pp. 2602–2612 [Abstract]
  • Ladislava Šebestová, Ivan Votruba and Antonín Holý
    S-adenosine-L-homocysteine hydrolase from Nicotiana tabacum L.: Isolation and properties
    1984, Vol. 49, Issue 6, pp. 1543–1551 [Abstract]
  • Aleš Merta, Ivan Votruba, Jiří Veselý and Antonín Holý
    S-adenosyl-L-homocysteine hydrolase from mouse leukemic cells: Isolation and properties
    1983, Vol. 48, Issue 9, pp. 2701–2708 [Abstract]
  • Ivan Votruba, Antonín Holý and Ivan Rosenberg
    Affinity chromatography of rat liver S-adenosyl-L-homocysteine hydrolase
    1983, Vol. 48, Issue 9, pp. 2549–2557 [Abstract]
  • Antonín Holý, Ivan Votruba and Erik De Clercq
    Synthesis and antiviral activity of stereoisomeric eritadenines
    1982, Vol. 47, Issue 5, pp. 1392–1407 [Abstract]
  • Ivan Votruba and Antonín Holý
    Eritadenines - Novel type of potent inhibitors of S-adenosyl-L-homocysteine hydrolase
    1982, Vol. 47, Issue 1, pp. 167–172 [Abstract]
  • Miroslav Janda, Jan Šrogl, Hana Dvořáková, Dalimil Dvořák and Ivan Stibor
    Electrooxidation of 2-arylfurans
    1981, Vol. 46, Issue 4, pp. 906–916 [Abstract]
  • Ivan Votruba and Antonín Holý
    Inhibition of S-adenosyl-L-homocysteine hydrolase by the aliphatic nucleoside analogue - 9-(S)-(2,3-dihydroxypropyl)adenine
    1980, Vol. 45, Issue 11, pp. 3039–3044 [Abstract]