Collect. Czech. Chem. Commun. 2006, 71, 434-442

An Unusual cis-Dichloro[17-(cyclobutylmethyl)-3-methoxymorphinan-14-ol-N,O]palladium(II) Complex

Alexandr Jegorova,*, Hana Petříčkováb, Bohumil Kratochvílb and Ivana Císařovác

a IVAX Pharmaceuticals, Research Unit, Branišovská 31, 370 05 České Budějovice, Czech Republic
b Department of Solid State Chemistry, Institute of Chemical Technology, Prague, Technická 5, 166 28 Prague 6, Czech Republic
c Department of Inorganic Chemistry, Faculty of Science, Charles University, Hlavova 8, 128 43 Prague 2, Czech Republic


Synthesis and crystal structure of cis-dichloro[17-(cyclobutylmethyl)-3-methoxymorphinan-14-ol-N,O]palladium(II) methanol solvate is reported. The title complex crystallises in the triclinic P1 space group and is remarkable both by the number of independent molecules in the unit cell and the coordination sphere of palladium(II) formed by tertiary alcohol, tertiary amine and two chlorine atoms.

Keywords: Morphinan; Opioids; Palladium complexes; Alkaloids; Hemilabile complex; X-Ray diffraction.

References: 28 live references.