Collect. Czech. Chem. Commun. 1991, 56, 449-458
https://doi.org/10.1135/cccc19910449

Potential antidepressants and inhibitors of 5-hydroxytryptamine and noradrenaline re-uptake in the brain: N,N-Dimethyl-(arylthio)thenylamines and N,N-dimethyl-2-(thienylthio)benzylamines

Karel Šindelář, Josef Pomykáček, Martin Valchář, Karel Dobrovský, Jiřina Metyšová and Zdeněk Polívka

Research Institute for Pharmacy and Biochemistry, 130 60 Prague 3

Individual author index pages


Other CCCC articles of these authors

  • Alexandra Šilhánková, Karel Šindelář, Karel Dobrovský, Ivan Krejčí, Jarmila Hodková and Zdeněk Polívka
    Synthesis of New L-Proline Amides with Anticonvulsive Effect
    1996, Vol. 61, Issue 7, pp. 1085–1092 [Abstract]
  • Vladimír Valenta, Karel Dobrovský, Ivan Krejčí and Zdeněk Polívka
    Potential Antagonists of Excitatory Amino Acids and Anticonvulsants: Some Heterocyclic (±)-Pyrrolidine-2-carboxamides
    1996, Vol. 61, Issue 7, pp. 1077–1084 [Abstract]
  • Karel Šindelář, Karel Dobrovský, Ivan Krejčí and Zdeněk Polívka
    Substituted 1-(2-Thienyl)cyclohexylamines and Related Compounds as Potential NMDA Antagonists
    1995, Vol. 60, Issue 5, pp. 894–902 [Abstract]
  • Vojtěch Kmoníček, Martin Valchář and Zdeněk Polívka
    Some 4-Substituted 1-(3-Pyridylmethyl)piperazines with Antihistamine Activity
    1994, Vol. 59, Issue 10, pp. 2343–2350 [Abstract]
  • Vladimír Valenta, Jiří Urban, Jan Taimr and Zdeněk Polívka
    Potential Nootropic Agents: Synthesis of Some 1,4-Disubstituted 2-Oxopyrrolidines and Some Related Compounds
    1994, Vol. 59, Issue 5, pp. 1126–1136 [Abstract]
  • Karel Šindelář, Alexandra Šilhánková, Jiří Urban, Jan Metyš, Martin Valchář and Zdeněk Polívka
    Antihistamine Substances. Tricyclic Analogues of N-(4,4-Diphenyl-3-butene-1-yl)nipecotic Acid and Some Related Compounds
    1994, Vol. 59, Issue 3, pp. 667–674 [Abstract]
  • Alexandra Šilhánková, Karel Dobrovský, Ivan Krejčí and Zdeněk Polívka
    Compounds Interacting with the Neuroexcitatory Amino Acids: Synthesis of 2-(4-Aralkylpiperazine-1-yl)-1-arylethanols
    1994, Vol. 59, Issue 3, pp. 658–666 [Abstract]
  • Karel Šindelář, Vojtěch Kmoníček, Marta Hrubantová and Zdeněk Polívka
    Substituted N,N-Dimethyl-3-(phenylthio)- and -4-(phenylthio)benzylamines
    1992, Vol. 57, Issue 1, pp. 194–203 [Abstract]
  • Karel Šindelář, Jiří Holoubek, Emil Svátek, Jan Metyš, Hana Blehová and Zdeněk Polívka
    Potential antihistaminics: Tricyclic carboxylic acids derived from 6,11-dihydrodibenzo[b,e]thiepine and 4,9-dihydrothieno[2,3-c]-2-benzothiepine
    1991, Vol. 56, Issue 11, pp. 2482–2493 [Abstract]
  • Vojtěch Kmoníček, Josef Pomykáček, Jiří Holoubek, Emil Svátek, Martin Valchář, Jiřina Metyšová and Zdeněk Polívka
    Potential antidepressants: 2-(fluoro-, chloro-, bromo- and cyanophenylthio)benzylamines as inhibitors of 5-hydroxytryptamine and noradrenaline re-uptake in brain
    1991, Vol. 56, Issue 11, pp. 2468–2481 [Abstract]
  • Vladimír Valenta, Marie Vlková, Martin Valchář, Karel Dobrovský and Zdeněk Polívka
    Potential antidepressants: 3-Aryl-3-(arylthio)propylamines as selective inhibitors of 5-hydroxytryptamine re-uptake in the brain
    1991, Vol. 56, Issue 7, pp. 1525–1533 [Abstract]
  • Karel Šindelář, Josef Pomykáček, Jiří Holubek, Emil Svátek, Martin Valchář, Karel Dobrovský, Jiřina Metyšová and Zdeněk Polívka
    Potential antidepressants and selective inhibitors of 5-hydroxytryptamine re-uptake in the brain: Synthesis of several potential metabolites of moxifetin and of two A-ring fluorinated analogues
    1991, Vol. 56, Issue 2, pp. 459–477 [Abstract]
  • Vladimír Valenta, Jiří Holubek, Emil Svátek, Martin Valchář, Ivan Krejčí and Miroslav Protiva
    Potential nootropic agents: Synthesis of some (2-oxo-1-pyrrolidinyl)acetamides and some related compounds
    1990, Vol. 55, Issue 11, pp. 2756–2764 [Abstract]
  • Karel Šindelář, Jiří Jílek, Josef Pomykáček, Vladimír Valenta, Marta Hrubantová, Marie Vlková, Jiří Holubek, Emil Svátek, Miroslav Ryska, Jiřina Metyšová and Miroslav Protiva
    Tricyclic neuroleptics: Synthesis of metabolites of isofloxythepin and some related compounds
    1990, Vol. 55, Issue 9, pp. 2282–2303 [Abstract]
  • Vojtěch Kmoníček, Emil Svátek, Jiří Holubek, Miroslav Ryska, Martin Valchář and Miroslav Protiva
    Synthesis of 1-acyl- and 1-(thioacyl)-4-benzylpiperazines as potential antidepressants
    1990, Vol. 55, Issue 7, pp. 1817–1827 [Abstract]
  • Vladimír Valenta, Karel Šindelář, Jiří Holubek, Miroslav Ryska, Ivan Krejčí, Antonín Dlabač and Miroslav Protiva
    Potential nootropic agents: Synthesis of a series of (2-oxo-1-pyrrolidinyl)acetic acid piperazides
    1990, Vol. 55, Issue 6, pp. 1613–1629 [Abstract]
  • Karel Šindelář, Jiří Holubek, Ivan Koruna, Marta Hrubantová and Miroslav Protiva
    Modified syntheses of 2-(methylthio)-10-(2-(1-methyl-2-piperidinyl)ethyl)phenothiazine (thioridazine) and 1-(3-(2-(methylsulfonyl)-10-phenothiazinyl)propyl)-piperidine-4-carboxamide (metopimazine)
    1990, Vol. 55, Issue 6, pp. 1586–1601 [Abstract]
  • Vladimír Valenta, Jiří Holubek, Emil Svátek, Oluše Matoušová, Jiřina Metyšová and Miroslav Protiva
    Potential neuroleptics of the orthopramide series; synthesis of heterocyclic 5-amino-2-methoxybenzamides and of some related compounds
    1990, Vol. 55, Issue 5, pp. 1297–1310 [Abstract]
  • Jiří Jílek, Karel Šindelář, Jaroslava Grimová, Eva Maturová, Jiří Holubek, Emil Svátek, Jiřina Metyšová, Jan Metyš, Marta Hrubantová and Miroslav Protiva
    Potential antidepressant and anti-inflammatory agents: 4-(2-Propylthio)acetophenone oximes and 4-(2-propylthio)phenylalkanoic acids
    1990, Vol. 55, Issue 5, pp. 1266–1277 [Abstract]
  • Jiří Urban, Zdeněk Šedivý, Jiří Holubek, Emil Svátek, Miroslav Ryska, Ivan Koruna, Antonín Dlabač, Martin Valchář, Jiřina Metyšová, Zdeněk Polívka, Karel Šindelář, Josef Pomykáček, Marta Hrubantová and Miroslav Protiva
    Potential antidepressants: 1-(2-(Methoxy- and hydroxyphenylthio)phenyl)-2-propylamines
    1990, Vol. 55, Issue 4, pp. 1077–1098 [Abstract]
  • Vladimír Valenta, Zdeněk Vejdělek, Karel Šindelář and Miroslav Protiva
    Potential anticonvulsants: Some derivatives and analogues of 2-propylpentanoic acid
    1990, Vol. 55, Issue 4, pp. 1067–1076 [Abstract]
  • Miloš Beran, Antonín Černý, Miroslav Kuchař, Hana Adamírová, Jiří Holubek, Jan Taimr, Jaroslav Vachek, Maria Frühaufová, Karel Řežábek, Martin Valchář and Ivan Krejčí
    9,10-Dihydroergopeptines modified in position 6
    1990, Vol. 55, Issue 3, pp. 819–832 [Abstract]
  • Vladimír Valenta, Marie Vlková, Jiří Holubek, Emil Svátek, Jiřina Metyšová and Miroslav Protiva
    Potential neuroleptics of the orthopramide series; Synthesis of N-(3-(tert.amino)propyl)-5-sulfamoyl-2-methoxybenzamides
    1990, Vol. 55, Issue 3, pp. 797–808 [Abstract]
  • Karel Šindelář, Jiří Holubek, Emil Svátek, Jiří Schlanger, Antonín Dlabač, Martin Valchář, Marta Hrubantová and Miroslav Protiva
    Open-ring models of hetero-cannabinoids: Synthesis of 2-(alkylthio)-5-(2-aminoethyl)hydroquinone derivatives
    1990, Vol. 55, Issue 3, pp. 782–796 [Abstract]
  • Karel Šindelář, Vladimír Valenta, Jiří Holubek, Oluše Matoušová and Miroslav Protiva
    Potential antidepressants. Synthesis of 6,11-dihydrodibenzo[b,e]thiepin-11-yl (dimethylaminomethyl)phenyl ethers, sulfides, amines and some related compounds
    1990, Vol. 55, Issue 1, pp. 282–295 [Abstract]
  • Jiří Jílek, Karel Šindelář, Josef Pomykáček, Vojtěch Kmoníček, Zdeněk Šedivý, Marta Hrubantová, Jiří Holubek, Emil Svátek, Miroslav Ryska, Ivan Koruna, Martin Valchář, Antonín Dlabač, Jiřina Metyšová, Nataša Dlohožková and Miroslav Protiva
    Potential antidepressants: 2-(Methoxy- and hydroxyphenylthio)benzylamines as selective inhibitors of 5-hydroxytryptamine re-uptake in the brain
    1989, Vol. 54, Issue 12, pp. 3294–3338 [Abstract]
  • Zdeněk Polívka, Miloš Buděšínský, Jiří Holubek, Bohdan Schneider, Zdeněk Šedivý, Emil Svátek, Oluše Matoušová, Jan Metyš, Martin Valchář, Radomír Souček and Miroslav Protiva
    4H-Benzo[4,5]cyclohepta[1,2-b]thiophenes and 9,10-dihydro derivatives - Sulfonium analogues of pizotifen and ketotifen; Chirality of ketotifen; Synthesis of the 2-bromo derivative of ketotifen
    1989, Vol. 54, Issue 9, pp. 2443–2469 [Abstract]
  • Jiří Jílek, Jiří Urban, Vojtěch Kmoníček, Josef Pomykáček, Jiří Holubek, Emil Svátek, Oluše Matoušová, Jan Metyš, Martin Valchář, Stanislav Wildt and Miroslav Protiva
    Potential anticonvulsants: 3-Chlorobenzophenone derivatives
    1989, Vol. 54, Issue 8, pp. 2248–2260 [Abstract]
  • Karel Šindelář, Marta Hrubantová, Emil Svátek, Oluše Matoušová, Jiřina Metyšová, Martin Valchář and Miroslav Protiva
    Potential antidepressants: 4-(Thioaryloxy)piperidines
    1989, Vol. 54, Issue 8, pp. 2240–2247 [Abstract]
  • Jiří Jílek, Jiří Urban, Petr Taufmann, Jiří Holubek, Antonín Dlabač, Martin Valchář and Miroslav Protiva
    Potential antidepressants: 2-(Phenylthio)aralkylamines
    1989, Vol. 54, Issue 7, pp. 1995–2008 [Abstract]
  • Vladimír Valenta, Marie Vlková, Jiří Holubek, Jiřina Metyšová and Miroslav Protiva
    Potential antidepressants: 10-Amino-2-chloro-10,11-dihydrodibenzo[b,f]thiepins
    1989, Vol. 54, Issue 7, pp. 1979–1994 [Abstract]
  • Vojtěch Kmoníček, Zdeněk Vejdělek, Jiří Holubek, Martin Valchář and Miroslav Protiva
    Potential antidepressants: 1-(4-Aminoalkoxy)phenyl)-2-propylamines
    1989, Vol. 54, Issue 6, pp. 1721–1733 [Abstract]
  • Zdeněk Polívka, Vladimír Valenta, Karel Šindelář, Jiří Holubek, Miloš Buděšínský, Miroslav Ryska, Ivan Koruna, Jitka Kohoutová, Jan Metyš, Jiřina Metyšová, Martin Valchář and Miroslav Protiva
    Potential antidepressants: Saturated side chain amines derived from 6,11-dihydrodibenzo[b,e]thiepin and 4,9-dihydrothieno[2,3-c]-2-benzothiepin
    1989, Vol. 54, Issue 1, pp. 235–247 [Abstract]
  • Karel Šindelář, Jiřina Metyšová and Miroslav Protiva
    Potential antidepressants: 2-(6,11-Dihydrodibenzo[b,e]thiepin-11-yl)-4,5-dihydroimidazoles
    1989, Vol. 54, Issue 1, pp. 229–234 [Abstract]
  • Irena Červená, Jiří Holubek, Emil Svátek, Jan Metyš, Martin Valchář and Miroslav Protiva
    Potential antidepressants: Synthesis of two 4-(aminoalkoxy)dibenzo[b,e]thiepin-11(6H)-ones
    1989, Vol. 54, Issue 1, pp. 225–228 [Abstract]
  • Jiří Jílek, Martin Valchář, Jiří Holubek, Nataša Dlohožková, Josef Pomykáček, Oluše Matoušová, Jiřina Metyšová and Miroslav Protiva
    Noncataleptic neuroleptic agents: 2-(4-(2-(2-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yloxy)ethyl)piperazine-1-yl)ethanol and some related compounds
    1988, Vol. 53, Issue 11, pp. 2731–2741 [Abstract]
  • Hana Hulinská, Zdeněk Polívka, Jiří Jílek, Karel Šindelář, Jiří Holubek, Emil Svátek, Oluše Matoušová, Miloš Buděšínský, Hana Frycová and Miroslav Protiva
    Experimental antiulcer agents: N-substituted 2-(4-methyl-1-piperazinyl)acetamides as pirenzepine models and some related compounds
    1988, Vol. 53, Issue 8, pp. 1820–1844 [Abstract]
  • Zdeněk Polívka, Jan Metyš and Miroslav Protiva
    6,11-Dihydrodibenzo[b,e]thiepin-11-yl 3-quinuclidinyl ethers: New potential intidepressants and antihistamine agents
    1988, Vol. 53, Issue 8, pp. 1806–1811 [Abstract]
  • Zdeněk Polívka, Jiřina Metyšová, Martin Valchář and Miroslav Protiva
    Potential antidepressants: N-phenacyl derivatives of (E)-N-methyl-3-(6,11-dihydrodibenzo[b,e]thiepin-11-ylidene)propylamine
    1988, Vol. 53, Issue 4, pp. 884–888 [Abstract]
  • Jiří Jílek, Jiří Holubek, Emil Svátek, Jan Metyš, Hana Frycová, Josef Pomykáček and Miroslav Protiva
    Tricyclic analogues of the antiallergic agent oxatomide: 1-(3-(4-(10,11-Dihydro-5H-dibenzo[a,d]cycloheptene-5-yl)-1-piperazinyl)propyl)-1,3-dihydro-2H-benzimidazol-2-one and the related 6,11-dihydrodibenzo[b,e]thiepin, 4,9-dihydrothieno[2,3-c]-2-benzothiepin, and 10,11-dihydrodibenzo[b,f]thiepin derivatives
    1988, Vol. 53, Issue 4, pp. 870–883 [Abstract]
  • Karel Šindelář, Zdeněk Šedivý, Marta Hrubantová, Martin Valchář, Jiřina Metyšová and Miroslav Protiva
    Synthesis of (2-(phenylthio)phenyl)acetamidines and related amidoximes as potential antidepressants
    1988, Vol. 53, Issue 2, pp. 381–388 [Abstract]
  • Karel Šindelář, Jiří Holubek, Oluše Matoušová, Emil Svátek, Martin Valchář, Antonín Dlabač, Nataša Dlohožková, Marta Hrubantová and Miroslav Protiva
    Aminoalkylidene and aminoalkyl derivatives of 6,11-dihydrodibenzo[b,e]thiepin-2- and -9-carbonitrile and 4,10-dihydrothieno[2,3-c]-1-benzothiepin-6-carbonitrile; Antidepressants with a new activity profile
    1988, Vol. 53, Issue 2, pp. 340–360 [Abstract]
  • Zdeněk Polívka, Jiří Holubek, Miloš Buděšínský, Oluše Matoušová, Emil Svátek, Jan Metyš and Miroslav Protiva
    Potential antihistamine agents: 4-(6,11-Dihydrodibenzo[b,e]thiepin-11-ylidene)-1-methyltetrahydrothiopyranium iodide and similar sulfonium salts derived from related tricyclic systems
    1987, Vol. 52, Issue 11, pp. 2758–2774 [Abstract]
  • Irena Červená, Jiří Holubek, Emil Svátek, Martin Valchář and Miroslav Protiva
    Potential antidepressants: 3-Methyl-6-dimethylamino-1,2-diphenylhexan-3-ol and related compounds
    1987, Vol. 52, Issue 10, pp. 2564–2571 [Abstract]
  • Karel Šindelář, Miloš Buděšínský, Tomáš Vaněk, Jiří Holubek, Emil Svátek, Oluše Matoušová, Charles Wayne Rees and Miroslav Protiva
    Reaction of 6,11-dihydrodibenzo[b,e]thiepin-11-carbonitrile with 1,2-dibromoethane, a reinvestigation. Formation of 11,12-dihydro-6H-6,12-methanodibenzo[b,f]thiocin-12-carbonitrile
    1987, Vol. 52, Issue 9, pp. 2281–2294 [Abstract]
  • Miroslav Protiva, Jiří Jílek, Miroslav Rajšner, Karel Šindelář, Václav Bártl, Miroslav Ryska, Ivan Koruna, Jiří Holubek, Emil Svátek, Jiřina Metyšová, Antonín Dlabač, Josef Pomykáček and František Mikšík
    Fluorinated tricyclic neuroleptics with prolonged action: derivatives and analogues of 2-(4-(7-fluoro-2-isopropyl-10,11-dihydrodibenzo[b,f]thiepin-11-yl)-piperazine-1-yl)ethanol
    1987, Vol. 52, Issue 7, pp. 1811–1833 [Abstract]
  • Zdeněk Polívka, Irena Lichá, Petr Taufmann, Emil Svátek, Jiří Holubek and Miroslav Protiva
    Synthesis of 3-(6,11-dihydrodibenzo[b,e]thiepin-11-ylidene)propanoic acid and related compounds
    1987, Vol. 52, Issue 6, pp. 1566–1582 [Abstract]
  • Vojtěch Kmoníček, Jiří Holubek, Emil Svátek, Jiřina Metyšová and Miroslav Protiva
    2-(tert.amino)-11-(4-methylpiperazino)dibenzo[b,f]thiepins and their 10,11-dihydro derivatives; Synthesis and neuroleptic activity
    1987, Vol. 52, Issue 3, pp. 793–803 [Abstract]
  • Karel Šindelář, Jiří Holubek, Miroslav Ryska, Ivan Koruna and Miroslav Protiva
    5-Substituted and 5,7-disubstituted 5,7-dihydrodibenzo[c,e]thiepins and the corresponding S-oxygenated compounds: Alkylamines, carboxylic acids, and carboxamides; synthesis and pharmacological screening
    1986, Vol. 51, Issue 12, pp. 2848–2868 [Abstract]
  • Miroslav Protiva, Jiří Jílek, Irena Červená, Josef Pomykáček, Václav Bártl, Antonín Dlabač, Martin Valchář, Jiřina Metyšová, Jiří Holubek and Emil Svátek
    Noncataleptic neuroleptic agents: 4-Substituted 1-(2-chloro-7-fluoro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazines and related compounds
    1986, Vol. 51, Issue 11, pp. 2598–2616 [Abstract]
  • Zdeněk Polívka, Jan Metyš and Miroslav Protiva
    Heterocyclic ethers derived from 6,11-dihydrodibenzo[b,e]thiepin-11-ols and 4,9-dihydrothieno[2,3-c]-2-benzothiepin-4-ol; A new series of potential antidepressants and antihistamine agents
    1986, Vol. 51, Issue 9, pp. 2034–2049 [Abstract]
  • Jiří Jílek, Martin Valchář, Josef Pomykáček, Antonín Dlabač and Miroslav Protiva
    Noncataleptic neuroleptic agents: Synthesis of some esters of 2-chloro-10-(4-(2-hydroxyethyl)piperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1986, Vol. 51, Issue 7, pp. 1503–1508 [Abstract]
  • Miroslav Protiva, Jiří Jílek, Miroslav Rajšner, Josef Pomykáček, Miroslav Ryska, Jiří Holubek, Emil Svátek and Jiřina Metyšová
    Fluorinated tricyclic neuroleptics with prolonged action: 7-Fluoro-11-[4-(2-hydroxyethyl)piperazino]-2-isopropyl-10,11-dihydrodibenzo[b,f]thiepin
    1986, Vol. 51, Issue 3, pp. 698–722 [Abstract]
  • Miroslav Protiva, Antonín Dlabač, Martin Valchář, Stanislav Wildt, Irena Červená and Zdeněk Šedivý
    Potential noncataleptic neuroleptic agents; 2,6-Dichloro-, 2,7-dichloro- and 2,8-dichloro-10-piperazino-10,11-dihydrodibenzo[b,f]thiepins
    1986, Vol. 51, Issue 1, pp. 156–166 [Abstract]
  • Irena Červená, Jiří Holubek, Emil Svátek, Jiřina Metyšová, Martin Valchář, Antonín Dlabač, Stanislav Wildt and Miroslav Protiva
    6-Substituted and 2-chloro-6-substituted 10-piperazino-10,11-dihydrodibenzo[b,f]thiepins as potential antidepressants; Synthesis and pharmacology
    1986, Vol. 51, Issue 1, pp. 141–155 [Abstract]
  • Jiří Jílek, Jiří Holubek, Emil Svátek, Jiřina Metyšová, Josef Pomykáček, Zdeněk Šedivý and Miroslav Protiva
    Potential metabolites of the neuroleptic agents belonging to the 8-methylthio-10-piperazino-10,11-dihydrodibenzo[b,f]thiepin series; Synthesis of 2-hydroxy and 3-hydroxy derivatives
    1985, Vol. 50, Issue 10, pp. 2179–2190 [Abstract]
  • Karel Šindelář, Jiří Holubek, Emil Svátek, Miroslav Ryska, Martin Valchář and Miroslav Protiva
    Butaclamol-like neuroleptic agents: Synthesis of 1-(11H-dibenz[b,f]-1,4-oxathiepin-11-yl)methyl-4-isobutylpiperidin-4-ol and of some related compounds
    1985, Vol. 50, Issue 7, pp. 1484–1497 [Abstract]
  • Karel Šindelář, Jan Metyš and Miroslav Protiva
    Potential antidiarrheal agents: 1-(11-Cyano-6,11-dihydrodibenzo[b,e]thiepin-11-yl-alkyl)- and 1-(10-cyano-10,11-dihydrodibenzo[b,f]thiepin-10-yl-alkyl)-4-substituted piperidines
    1985, Vol. 50, Issue 5, pp. 1089–1096 [Abstract]
  • Zdeněk Polívka, Jiří Holubek, Emil Svátek, Jan Metyš and Miroslav Protiva
    Synthesis of the semi-rigid analogues of prothiadene and dithiadene as potential antidepressant and antihistamine agents: 11-[2-(Dimethylaminomethyl)cyclohexylidene]-6,11-dihydrodibenzo[b,e]thiepins and 4-[2-(dimethylaminomethyl)cyclohexylidene]-4,9-dihydrothieno-[2,3-c]-2-benzothiepins
    1985, Vol. 50, Issue 5, pp. 1078–1088 [Abstract]
  • Vladimír Valenta, Zdeněk Prošek, Jiřina Metyšová, Martin Valchář, Antonín Dlabač and Miroslav Protiva
    Cataleptic and noncataleptic neuroleptic agents: Synthesis and pharmacology of 4-(2-chloro and 8-chloro substituted 10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine-1-ylalkyl ethers and sulfides
    1985, Vol. 50, Issue 5, pp. 1070–1077 [Abstract]
  • Zdeněk Vejdělek, Zdeněk Polívka and Miroslav Protiva
    Synthesis of 7-chloro-5-(4-chlorophenyl)-1-methyl-1,3-dihydro-1,4-benzodiazepin-2-one
    1985, Vol. 50, Issue 5, pp. 1064–1069 [Abstract]
  • Jiří Jílek, Jiří Holubek, Emil Svátek, Jiří Schlanger, Josef Pomykáček and Miroslav Protiva
    Highly polar potential metabolites of the neuroleptic agent oxyprothepin: Synthesis of 2-hydroxy-8-methylsulfonyl and 3-hydroxy-8-methylsulfonyl derivatives of 10-[4-(3-hydroxypropyl)piperazino]-10,11-dihydrodibenzo[b,f]thiepin
    1985, Vol. 50, Issue 2, pp. 519–537 [Abstract]
  • Karel Šindelář, Jiří Holubek, Jiří Schlanger, Antonín Dlabač, Martin Valchář and Miroslav Protiva
    Synthesis of spiro(piperidine-4,6'-dibenz[b,e]-1,4-oxathiepin) and its 1-methyl derivative as potential antidepressant agents
    1985, Vol. 50, Issue 2, pp. 503–509 [Abstract]
  • Jiří Jílek, Miroslav Rajšner, Jiřina Metyšová, Josef Pomykáček and Miroslav Protiva
    Fluorinated tricyclic neuroleptics with prolonged action: 8-Alkyl derivatives of 3-fluoro-10-piperazino-10,11-dihydrodibenzo[b,f]thiepins
    1984, Vol. 49, Issue 11, pp. 2638–2648 [Abstract]
  • Karel Šindelář, Jiří Holubek, Miroslav Ryska, Antonín Dlabač, Martin Valchář, Jiřina Metyšová and Miroslav Protiva
    Tricyclic compounds containing two chalcogen atoms in the central seven-membered rings as potential drugs: Synthesis of 3-chloro-6-(1-methyl-4-piperidyl)-6H-dibenz[b,e]-1,4-oxathiepin and 6-oxodibenz[b,e]-1,4-oxathiepin-2-acetic acid
    1984, Vol. 49, Issue 11, pp. 2531–2540 [Abstract]
  • Václav Bártl, Karel Šindelář, Vladimír Valenta, Jiří Holubek, Emil Svátek, Jiří Schlanger, Antonín Dlabač, Jiřina Metyšová and Miroslav Protiva
    Potential antipsychotic agents: 2-Chloro- and 2-methyl-11-(2-piperazinoethoxy)-6,11-dihydrodibenzo[b,e]thiepins and some related compounds; Synthesis and pharmacology
    1984, Vol. 49, Issue 11, pp. 2520–2530 [Abstract]
  • Václav Bártl, Jiří Jílek, Jiřina Metyšová, Martin Valchář, Antonín Dlabač, Stanislav Wildt and Miroslav Protiva
    Neuroleptic 2-chloro-11-(2-piperazineethoxy)-10,11-dihydrodibenzo[b,f]thiepins: Synthesis and pharmacology
    1984, Vol. 49, Issue 8, pp. 1810–1815 [Abstract]
  • Václav Bártl, Antonín Dlabač, Martin Valchář and Miroslav Protiva
    11-(4-Piperidylidene)-6,11-dihydrodibenzo[b,e]thiepins as potential antipsychotic agents; Synthesis and pharmacology
    1984, Vol. 49, Issue 8, pp. 1800–1809 [Abstract]
  • Karel Šindelář, Jiří Holubek, Miroslav Ryska, Emil Svátek, Antonín Dlabač, Martin Valchář and Miroslav Protiva
    Analogues of the neuroleptic agent isobutaclamol: Stereoisomeric 3b,4,5,6,7,9,9a,10-octahydro-[1]benzothiepino[2,3,4-ed]pyrido[2,1-a]isoquinolin-5-ols and some related compounds
    1984, Vol. 49, Issue 4, pp. 1021–1038 [Abstract]
  • Vladimír Valenta, Antonín Dlabač, Martin Valchář and Miroslav Protiva
    α-Benzyldopamine and some related compounds: Synthesis and pharmacological screening
    1984, Vol. 49, Issue 4, pp. 1002–1008 [Abstract]
  • Jiří Urban, Antonín Dlabač, Martin Valchář and Miroslav Protiva
    Potential noncataleptic neuroleptic agents: 2,3-Dichloro-10-[4-(2-hydroxyethyl)piperazino]-10,11-dihydrobenzo[b,f]thiepin
    1984, Vol. 49, Issue 4, pp. 992–1001 [Abstract]
  • Zdeněk Polívka, Jiří Holubek, Emil Svátek, Jan Metyš and Miroslav Protiva
    Potential hypnotics and anxiolytics: Synthesis of 2-bromo-4-(2-chlorophenyl)-9-[4-(2-methoxyethyl)piperazino]-6H-thieno[3,2,4-triazolo[4,3-a]-1,4-diazepine and of some related compounds
    1984, Vol. 49, Issue 3, pp. 621–636 [Abstract]
  • Jiří Jílek, Josef Pomykáček, Jiří Holubek, Emil Svátek, Miroslav Ryska, Jiří Protiva and Miroslav Protiva
    Reactions of 4,4'-disubstituted diphenyl sulfides with chloroacetyl chloride and aluminium chloride
    1984, Vol. 49, Issue 3, pp. 603–620 [Abstract]
  • Zdeněk Polívka, Jiří Jílek, Jiří Holubek, Emil Svátek, Antonín Dlabač, Martin Valchář and Miroslav Protiva
    Noncataleptic neuroleptic agents: 2-Halogeno-8-isopropyl-10-piperazino-10,11-dihydrodibenzo[b,f,]thiepins
    1984, Vol. 49, Issue 1, pp. 86–109 [Abstract]
  • Zdeněk Polívka, Jiří Holubek, Jan Metyš, Zdeněk Šedivý and Miroslav Protiva
    Potential hypnotics and anxiolytics: 8-Chloro-6-(2-chlorophenyl)-1-[4-(2-methoxyethyl)piperazino]-methyl-4H-s-triazolo[4,3-a]-1,4-benzodiazepine and related compounds
    1983, Vol. 48, Issue 12, pp. 3433–3443 [Abstract]
  • Zdeněk Polívka, Martin Valchář and Miroslav Protiva
    Potential noncataleptic neuroleptic agents: Synthesis and pharmacology of 7-chloro-4-[4-(2-hydroxyethyl)piperazino]-4,5-dihydrothieno[2,3-b]-1-benzothiepin
    1983, Vol. 48, Issue 10, pp. 2970–2976 [Abstract]
  • Zdeněk Polívka, Miroslav Ryska, Jiří Holubek, Emil Svátek, Jan Metyš and Miroslav Protiva
    Potential hypnotics and anxiolytics in the 4H-s-triazolo[4,3-a]-1,4-benzodiazepine series: 8-Chloro-6-(2-chlorophenyl)-1-[4-(2-methoxyethyl)piperazino]-4H-s-triazolo[4,3-a]-1,4-benzodiazepine and some related compounds
    1983, Vol. 48, Issue 8, pp. 2395–2410 [Abstract]
  • Karel Šindelář, Jiří Holubek, Miroslav Ryska, Emil Svátek, Jiří Urban and Miroslav Protiva
    11-(Dimethylaminoalkyl)-6,11-dihydrodibenzo[b,e]thiepin-11-carbonitriles and some related compounds
    1983, Vol. 48, Issue 7, pp. 1898–1909 [Abstract]
  • Zdeněk Polívka, Jiří Holubek, Emil Svátek, Antonín Dlabač, Dušan Půček, Zdeněk Šedivý and Miroslav Protiva
    3-(4-Methylpiperazino)dibenzo[b,f]-1,2,4-triazolo[4,3-d]-1,4-thiazepine and its 6-chloro and 12-chloro derivatives; Synthesis and pharmacology
    1983, Vol. 48, Issue 5, pp. 1465–1476 [Abstract]
  • Karel Šindelář, Jiří Holubek, Miroslav Ryska, Emil Svátek, Jiří Urban, Jaroslava Grimová, Irena Červená, Marta Hrubantová and Miroslav Protiva
    Dibenzo[b,f]thiepin-10-carbonitrile, its 10,11-dihydro derivative, some transformation products and related compounds
    1983, Vol. 48, Issue 4, pp. 1187–1211 [Abstract]
  • Jiří Jílek, Josef Pomykáček, Zdeněk Prošek, Jiří Holubek, Emil Svátek, Jiřina Metyšová, Antonín Dlabač and Miroslav Protiva
    8-Chloro and 8-methylthio derivatives of 10-piperazino-10,11-dihydrodibenzo[b,f]thiepins; New compounds and new procedures
    1983, Vol. 48, Issue 3, pp. 906–927 [Abstract]
  • Zdeněk Polívka, Miroslav Rajšner, Jan Metyš, Jiří Holubek, Emil Svátek, Miroslav Ryska and Miroslav Protiva
    Antiaminic agents derived from thieno[2,3-c]-2-benzothiepin: 4-(1-Methyl-4-piperidylidene)-4,9-dihydrothieno[2,3-c]-2-benzothiepin and some related compounds
    1983, Vol. 48, Issue 2, pp. 623–641 [Abstract]
  • Karel Šindelář, Jiřina Metyšová, Jiří Holubek, Emil Svátek, Miroslav Ryska and Miroslav Protiva
    Fluorinated tricyclic neuroleptics with prolonged action: 3-Fluoro-10-[4-(2-hydroxyethyl)piperazino]-10,11-dihydrodibenzo[b,f]thiepins with less common substituents in position 8
    1983, Vol. 48, Issue 1, pp. 144–155 [Abstract]
  • Miroslav Protiva, Zdeněk Šedivý, Jiří Holubek, Emil Svátek, Jiřina Metyšová and Marie Bartošová
    Potential psychotropic and antihistamine agents: 1- and 3-alkyl-9-(3-dimethylaminopropylidene)-thioxanthenes and 3-alkyl-11-piperazino-10,11-dihydrodibenzo[b,f]thiepins
    1982, Vol. 47, Issue 11, pp. 3134–3147 [Abstract]
  • Karel Šindelář, Jiří Holubek, Emil Svátek, Miroslav Ryska, Antonín Dlabač, Jiřina Metyšová and Miroslav Protiva
    Tricyclic psychotropic agents containing two chalcogen atoms in the central ring: 2-Fluoro-8-substituted 6-(4-piperidyl)-6H-dibenz[b,e]-1,4-oxathiepins
    1982, Vol. 47, Issue 11, pp. 3114–3133 [Abstract]
  • Miroslav Protiva, Karel Šindelář, Vladimír Valenta, Jiří Holubek, Emil Svátek, Miroslav Ryska, Jiří Schlanger, Jiří Urban and Marta Hrubantová
    Reactions of 11-chloro-11-phenyl-6,11-dihydrodibenzo[b,e]-thiepin with piperidine and some further nucleophiles
    1982, Vol. 47, Issue 11, pp. 3094–3113 [Abstract]
  • Karel Šindelář, Jiřina Metyšová, Jiří Holubek, Emil Svátek, Jiří Protiva and Miroslav Protiva
    Tricyclic psychotropic agents containing two chalcogen atoms in the central ring: 8-Substituted 6-(4-piperidyl)-6H-dibenz[b,e]-1,4-oxathiepins
    1982, Vol. 47, Issue 11, pp. 3077–3093 [Abstract]
  • Jiří Jílek, Josef Pomykáček, Jiřina Metyšová and Miroslav Protiva
    Fluorinated tricyclic neuroleptics with prolonged action: 8-Methoxy, 8-ethoxy, 8-ethylthio and 8-hydroxy derivatives of 3-fluoro-10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1982, Vol. 47, Issue 5, pp. 1382–1391 [Abstract]
  • Karel Šindelář, Jiří Holubek, Emil Svátek, Miroslav Ryska, Antonín Dlabač and Miroslav Protiva
    Tricyclic psychotropic agents containing two chalcogen atoms in the central ring: Synthesis of 6-(aminoalkyl) derivatives of 6H-dibenz[b,e]-1,4-oxathiepin
    1982, Vol. 47, Issue 5, pp. 1367–1381 [Abstract]
  • Karel Šindelář, Jiří Holubek, Miroslav Ryska, Antonín Dlabač, Jiřina Metyšová, Emil Svátek, Marta Hrubantová, Jiří Protiva and Miroslav Protiva
    Tricyclic psychotropic agents containing two chalcogen atoms in the central ring: Derivatives of 11H-dibenz[b,f]-1,4-oxathiepin
    1982, Vol. 47, Issue 3, pp. 967–983 [Abstract]
  • Karel Šindelář, Jiří Holubek, Miroslav Ryska, Emil Svátek, Antonín Dlabač, Marta Hrubantová and Miroslav Protiva
    Tricyclic psychotropic agents containing two chalcogen atoms in the central ring: Synthesis of 11-(dimethylaminoalkyl) derivatives of 11H-dibenzo[b,e]-1,4-dioxepin and 11H-dibenzo[b,e]-1,4-dithiepin
    1982, Vol. 47, Issue 1, pp. 72–87 [Abstract]
  • Jiří Jílek, Josef Pomykáček, Jiří Němec and Miroslav Protiva
    1-(3-Dimethylamino-1-phenylpropyl)piperazines and related compounds: Synthesis and pharmacological screening
    1981, Vol. 46, Issue 11, pp. 2729–2733 [Abstract]
  • Miroslav Protiva, Zdeněk Šedivý, Josef Pomykáček, Václav Bártl, Jiří Holubek and Emil Svátek
    Potential metabolites of the noncataleptic neuroleptics: Synthesis of 2-chloro-6-hydroxy(and methoxy)-10-[4-(2-hydroxyethyl)piperazino]-10,11-dihydrodibenzo[b,f]thiepin
    1981, Vol. 46, Issue 9, pp. 2245–2253 [Abstract]
  • Zdeněk Polívka, Jiří Holubek, Emil Svátek, Jiřina Metyšová and Miroslav Protiva
    Fluorinated tricyclic neuroleptics: Synthesis and pharmacology of 2-chloro-8-fluoro-4-(4-methylpiperazino)-4,5-dihydrothieno[2,3-b]-1-benzothiepin
    1981, Vol. 46, Issue 9, pp. 2222–2233 [Abstract]
  • Miroslav Protiva, Karel Šindelář, Zdeněk Šedivý, Jiří Holubek and Marie Bartošová
    Potential metabolites of tricyclic neuroleptics: 3,7-Dimethoxy and 7,8-dimethoxy derivatives of 10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1981, Vol. 46, Issue 8, pp. 1808–1817 [Abstract]
  • Miroslav Protiva, Karel Šindelář, Jiřina Metyšová, Jiří Holubek, Miroslav Ryska, Emil Svátek, Zdeněk Šedivý and Josef Pomykáček
    Fluorinated tricyclic neuroleptics with prolonged action: 3-Fluoro-8-halogeno derivatives of 10-piperazino-10,11-dihydrodibenzo[b,f]thiepins
    1981, Vol. 46, Issue 8, pp. 1788–1799 [Abstract]
  • Jiří Jílek, Josef Pomykáček, Jiřina Metyšová and Miroslav Protiva
    Neuroleptic agents derived from perathiepin: 6,7-Dichloro derivative of 10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin and related compounds
    1981, Vol. 46, Issue 7, pp. 1607–1613 [Abstract]
  • Miroslav Protiva, Zdeněk Šedivý, Josef Pomykáček, Emil Svátek and Jiří Holubek
    Potential metabolites of the neuroleptic agent octoclothepin; Synthesis of 8-chloro-2,6-dihydroxy and 8-chloro-3,6-dihydroxy derivatives of 10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1981, Vol. 46, Issue 5, pp. 1199–1209 [Abstract]
  • Karel Šindelář, Jiří Holubek, Jan Metyš, Marie Bartošová and Miroslav Protiva
    Synthesis of 3-(2-alkoxyphenoxy)-2-methyl (or phenyl)propylamines as potential antidepressants
    1981, Vol. 46, Issue 3, pp. 597–606 [Abstract]
  • Václav Bártl, Jiřina Metyšová and Miroslav Protiva
    2-Chloro-7-fluoro- and 2-chloro-3,7-difluoro-11-[4-(4-fluoroaralkyl)piperazino]-10,11-dihydrodibenzo-[b,f]thiepins and related compounds; Long acting tranquillizers
    1981, Vol. 46, Issue 1, pp. 141–147 [Abstract]
  • Karel Šindelář, Miroslav Ryska, Jiří Holubek, Emil Svátek, Jiřina Metyšová, Jiří Protiva and Miroslav Protiva
    Fluorinated tricyclic neuroleptics with prolonged action: 3-Fluoro-8-trifluoromethyl derivatives of 10-(4-methylpiperazino)- and 10-[4-(2-hydroxyethyl)piperazino]-10,11-dihydrodibenzo-[b,f]thiepin
    1981, Vol. 46, Issue 1, pp. 118–140 [Abstract]
  • Karel Šindelář, Jiří Jílek, Jiří Körbl, Fedir Jančik, Emil Svátek, Jiřina Metyšová and Miroslav Protiva
    Potential metabolites of the neuroleptic agent chlorprothixene; synthesis and pharmacology of the 3-, 4-, 6- and 7-hydroxy and methoxy derivatives of 2-chloro-9-(3-dimethylaminopropylidene)-thioxanthenes
    1980, Vol. 45, Issue 11, pp. 3166–3181 [Abstract]
  • Irena Červená, Marta Hrubantová, Emil Svátek, Jiří Holubek, Miroslav Ryska, Jiřina Metyšová and Miroslav Protiva
    Fluorinated analogues of tricyclic neuroleptics: 6,9-difluoro derivative of 10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1980, Vol. 45, Issue 10, pp. 2688–2694 [Abstract]
  • Karel Šindelář, Emil Svátek, Jiří Holubek, Miroslav Ryska, Jiřina Metyšová, Zdeněk Šedivý and Miroslav Protiva
    Fluorinated analogues of the tricyclic neuroleptics; 7-Fluoro and 7-trifluoromethyl derivative of 10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1980, Vol. 45, Issue 4, pp. 1086–1098 [Abstract]
  • Jiří Jílek, Josef Pomykáček, Antonín Dlabač, Marie Bartošová and Miroslav Protiva
    Neuroleptics of the 8-methylthio-10-piperazino-10,11-dihydrodibenzo[b,f]thiepin series: New compounds and new procedures
    1980, Vol. 45, Issue 2, pp. 504–516 [Abstract]
  • Karel Šindelář, Jiří Holubek, Emil Svátek and Miroslav Protiva
    Synthesis of 3-chloro-5-(4-methylpiperazino)-6,7-dihydro-5H-dibenzo[b,g]thiocin, an eight-membered ring homologue of the neuroleptic agent octoclothepin
    1980, Vol. 45, Issue 2, pp. 491–503 [Abstract]
  • Karel Šindelář, Jiří Holubek, Emil Svátek, Miroslav Ryska, Jiřina Metyšová, Zdeněk Šedivý and Miroslav Protiva
    Potential metabolites of the neuroleptic agents noroxyclothepin and oxyclothepin; Synthesis of 8-chloro-3-hydroxy-10-[4-(2-hydroxyethyl)piperazino]- and -10-[4-(3-hydroxypropyl)piperazino]-10,11-dihydrodibenzo[b,f]thiepin
    1979, Vol. 44, Issue 12, pp. 3617–3626 [Abstract]
  • Miroslav Rajšner, František Mikšík, Jiřina Metyšová and Miroslav Protiva
    Fluorinated tricyclic neuroleptics: Synthesis and pharmacology of 8-fluoro-4-(4-methylpiperazino)-4,5-dihydrothieno[2,3-b]-1-benzothiepin
    1979, Vol. 44, Issue 10, pp. 2997–3007 [Abstract]
  • Miroslav Protiva, Karel Šindelář, Zdeněk Šedivý and Josef Pomykáček
    Potential metabolites of tricyclic neuroleptics: 2,8-Dihydroxy and 3,8-dihydroxy derivatives of 10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1979, Vol. 44, Issue 10, pp. 2987–2996 [Abstract]
  • Vladimír Valenta, Jiří Jílek, Josef Pomykáček, Antonín Dlabač, Martin Valchář, Jan Metyš and Miroslav Protiva
    Noncataleptic potential neuroleptics: 2-Methyl-10-(4-methylpiperazino)- and -10-[4-(2-hydroxyethyl)piperazino]-10,11-dihydrodibenzo[b,f]thiepin
    1979, Vol. 44, Issue 9, pp. 2677–2688 [Abstract]
  • Miroslav Rajšner, Václav Bártl, Karel Šindelář, Emil Svátek, Jiří Holubek, Jan Metyš and Miroslav Protiva
    Synthesis of new dibenzo[b,e]thiepin derivatives related to the antidepressant agent prothiadene
    1979, Vol. 44, Issue 8, pp. 2536–2549 [Abstract]
  • Irena Červená, Jiřina Metyšová, Václav Bártl and Miroslav Protiva
    Fluorinated neuroleptics of the 10-piperazino-10,11-dihydrodibenzo[b,f]thiepin series; 6-Fluoro derivatives of perathiepin, octoclothepin, doclothepin and some related compounds
    1979, Vol. 44, Issue 7, pp. 2139–2155 [Abstract]
  • Jiří O. Jílek, Jiří Holubek, Emil Svátek, Miroslav Ryska, Josef Pomykáček and Miroslav Protiva
    Reaction of some 3-(phenylthioaryl)propionic acids with polyphosphoric acid; Formation of 2H-cyclopenta[k,l]thioxanthenes
    1979, Vol. 44, Issue 7, pp. 2124–2138 [Abstract]
  • Miroslav Protiva, Karel Šindelář, Zdeněk Šedivý and Jiřina Metyšová
    Potential metabolites of tricyclic neuroleptics and their fluorinated analogues; 3-Hydroxy-, 3-methoxy- and 3-fluoro-10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin
    1979, Vol. 44, Issue 7, pp. 2108–2123 [Abstract]
  • Jiří Jílek, Jiří Holubek, Emil Svátek, Marie Bartošová, Jiřina Metyšová, Josef Pomykáček and Miroslav Protiva
    8-Chloro-3-hydroxy-10-piperazino-10,11-dihydrodibenzo[b,f]thiepins, their O-methyl derivatives and further potential metabolites of the neuroleptic agent octoclothepin
    1978, Vol. 43, Issue 11, pp. 3092–3102 [Abstract]
  • Miroslav Protiva, Irena Červená, Miroslav Rajšner, Jiřina Metyšová and Marta Hrubantová
    Fluorinated tricyclic neuroleptics: 3-Fluoro and 3,6-difluoro derivatives of chlorprothixene and 6-fluoro-2-isopropyl derivative of prothixene
    1978, Vol. 43, Issue 10, pp. 2656–2663 [Abstract]
  • Jiří O. Jílek, Josef Pomykáček, Jiřina Metyšová, Marie Bartošová and Miroslav Protiva
    Potential metabolites of the neuroleptic agent octoclothepin; Synthesis and pharmacology of 8-chloro-6-hydroxy-10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin and some related compounds
    1978, Vol. 43, Issue 7, pp. 1747–1759 [Abstract]
  • Karel Šindelář, Jiří O. Jílek, Josef Pomykáček, Zdeněk Šedivý and Miroslav Protiva
    Synthesis of 2-acetyl and 3-acetyl derivatives of 8-chloro-10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]-thiepin; 2-Acyl-7-substituted thioxanthenes
    1978, Vol. 43, Issue 2, pp. 471–497 [Abstract]
  • Karel Šindelář, Antonín Dlabač and Miroslav Protiva
    Noncataleptic neuroleptics; 8-Chloro-2-hydroxy-11-(4-methylpiperazino)-5H-dibenzo[b,e]-1,4-diazepine as a potential metabolite of clozapine
    1978, Vol. 43, Issue 1, pp. 309–315 [Abstract]