Collect. Czech. Chem. Commun. 1988, 53, 1812-1819
https://doi.org/10.1135/cccc19881812

Synthesis and biological activity of some basic-substituted 4,9-dihydro-3-methyl-4-oxo-1H(2H)-pyrazolo[3,4-b]quinolines

Stanislav Rádl and Viktor Zikán

Research Institute for Pharmacy and Biochemistry, 130 60 Prague 3

Individual author index pages


Other CCCC articles of these authors

  • Stanislav Rádl*, Jan Stach, Josef Černý and Ondřej Klecán
    An efficient synthesis of 6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine, a key intermediate in the licofelone synthesis
    2009, Vol. 74, Issue 6, pp. 1011–1022 [Abstract]
  • Jaroslav Havlíček*, Zuzana Mandelová, Ruediger Weisemann, Ivo Střelec, Lukáš Plaček and Stanislav Rádl
    Identification, synthesis and structural determination of some impurities of candesartan cilexetil
    2009, Vol. 74, Issue 2, pp. 347–362 [Abstract]
  • Jan Stach*, Jaroslav Havlíček, Lukáš Plaček and Stanislav Rádl
    Synthesis of Some Impurities and/or Degradation Products of Atorvastatin
    2008, Vol. 73, Issue 2, pp. 229–246 [Abstract]
  • Stanislav Rádl*, Ondřej Klecán, Robert Klvaňa and Jaroslav Havlíček
    A New Synthesis of Rizatriptan Based on Radical Cyclization
    2008, Vol. 73, Issue 1, pp. 116–126 [Abstract]
  • Stanislav Rádl* and Iva Obadalová
    Utilization of Aromatic Denitrocyclization Reaction for the Synthesis of 3-Unsubstituted 1,4-Dihydroquinolin-4-one Derivatives
    2004, Vol. 69, Issue 4, pp. 822–832 [Abstract]
  • Stanislav Rádl*, Petr Hezký, Petr Konvička and Ivan Krejčí
    Synthesis and Analgesic Activity of Some Substituted 1-Benzofurans and 1-Benzothiophenes
    2000, Vol. 65, Issue 7, pp. 1093–1108 [Abstract]
  • Stanislav Rádl*, Petr Hezký, Jitka Urbánková, Petr Váchal and Ivan Krejčí
    Synthesis and Analgesic Activity of Some 1-Benzofurans, 1-Benzothiophenes and Indoles
    2000, Vol. 65, Issue 2, pp. 280–296 [Abstract]
  • Stanislav Rádl*, Wieland Hafner, Petr Hezký, Ivan Krejčí, Jan Proška and Josef Hájíček
    Synthesis and Antinociceptive Activity of Some 3-Chlorophenyl- and 6-Chloropyridin-2-yl Derivatives
    1999, Vol. 64, Issue 2, pp. 377–388 [Abstract]
  • Stanislav Rádl*, Wieland Hafner, Petr Hezký, Ivan Krejčí, Jan Proška and Jan Taimr
    Molecular Modification of Anpirtoline, a Non-Opioid Centrally Acting Analgesic
    1999, Vol. 64, Issue 2, pp. 363–376 [Abstract]
  • Stanislav Rádl
    Synthetic Studies Connected with the Preparation of 4-Cyclopropyl-7-fluoro-6-(4-methylpiperazin-1-yl)-1,2,4,9-tetrahydrothiazolo[5,4-b]quinoline-2,9-dione
    1997, Vol. 62, Issue 5, pp. 791–799 [Abstract]
  • Stanislav Rádl
    Preparation of 1-Hydroxyxanthen-9(9H)-ones and 1-Hydroxyacridin-9(10H)-ones via Corresponding 3,4-Dihydro-1,9(2H)-diones
    1995, Vol. 60, Issue 12, pp. 2127–2136 [Abstract]
  • Stanislav Rádl
    Synthesis of 3-Amino- and 3-Acylamino-1-cyclopropylquinolin-4(1H)-ones
    1994, Vol. 59, Issue 9, pp. 2123–2126 [Abstract]
  • Stanislav Rádl
    Synthesis of Ethyl 1-Ethyl-6-fluoro-1,4-dihydro-8-hydroxy-4-oxoquinoline-3-carboxylate
    1994, Vol. 59, Issue 9, pp. 2119–2122 [Abstract]
  • Stanislav Rádl
    Preparation of Some Pyrazole Derivatives by Extrusion of Elemental Sulfur from 1,3,4-Thiadiazines
    1992, Vol. 57, Issue 3, pp. 656–659 [Abstract]
  • Stanislav Rádl, Jaroslav Moural and Radoslava Bendová
    Preparation of Some 2,3-Dihydro-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine Derivatives
    1992, Vol. 57, Issue 1, pp. 216–218 [Abstract]
  • Stanislav Rádl and Lenka Kovářová
    Preparation of Some Substituted 9,10-Dihydro-1-hydroxy-9-oxoacridine Derivatives
    1992, Vol. 57, Issue 1, pp. 212–215 [Abstract]
  • Stanislav Rádl and Magda Janichová
    Synthesis and Antibacterial Activity of Some 3-Hydroxyquinolones
    1992, Vol. 57, Issue 1, pp. 188–193 [Abstract]
  • Stanislav Rádl and Pavel Hradil
    Synthesis of some 1-alkyl-1,4-dihydro-4-oxo-1,7-naphthyridine-3-carboxylic acids
    1991, Vol. 56, Issue 11, pp. 2420–2429 [Abstract]
  • Stanislav Rádl and Lenka Kovářová
    Some reactions of N-propadienyl-4-quinolones
    1991, Vol. 56, Issue 11, pp. 2413–2419 [Abstract]
  • Stanislav Rádl and Lenka Kovářová
    Synthesis and antibacterial activity of new 7-substituted fluoroquinolones
    1991, Vol. 56, Issue 11, pp. 2406–2412 [Abstract]
  • Stanislav Rádl, Lenka Kovářová, Jaroslav Moural and Radoslava Bendová
    Structural modification and new methods for preparation of ofloxacin analogs
    1991, Vol. 56, Issue 9, pp. 1937–1943 [Abstract]
  • Stanislav Rádl, Lenka Kovářová and Jiří Holoubek
    Synthesis and antibacterial activity of some 1-(2-propynyl) and 1-propadienyl derivatives of 1,4-dihydro-4-oxoquinoline-3-carboxylic acids and similar heterocycles
    1991, Vol. 56, Issue 2, pp. 439–448 [Abstract]
  • Stanislav Rádl, Jaroslav Moural and Radoslava Bendová
    Synthesis and antibacterial activity of some 1-aryl-1,4-dihydro-4-oxocinnoline-3-carboxylic acids
    1990, Vol. 55, Issue 5, pp. 1311–1320 [Abstract]
  • Stanislav Rádl and Viktor Zikán
    Synthesis of some 1-aryl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids and their antibacterial activity
    1989, Vol. 54, Issue 8, pp. 2181–2189 [Abstract]
  • Stanislav Rádl and Viktor Zikán
    Synthesis and antimicrobial activity of some 3-oxo-3H-pyrido[3,2,1-kl]phenoxazine-2-carboxylic acids
    1989, Vol. 54, Issue 2, pp. 506–515 [Abstract]
  • Stanislav Rádl and Viktor Zikán
    Synthesis of 1,2, and 9-methyl derivatives of 4,9-dihydro-6-methoxy-3-methyl-4-oxo-1H(2H)-pyrazolo[3,4-b]quinoline and 4,9-dihydro-6-hydroxy-3-methyl-4-oxo-1H(2H)-pyrazolo[3,4-b]quinoline and their antiviral activity
    1987, Vol. 52, Issue 3, pp. 788–792 [Abstract]
  • Stanislav Rádl and Viktor Zikán
    Syntheses of some 4-dialkylaminoalkylamino derivatives of 2,3-dimethyl-2H- and 3,9-dimethyl-9H-pyrazolo[3,4-b]quinoline
    1986, Vol. 51, Issue 8, pp. 1692–1697 [Abstract]
  • Stanislav Rádl, Viktor Zikán and František Šmejkal
    Syntheses of some N-carboxymethyl derivatives of 4,9-dihydro-3-methyl-4-oxo-1H-(2H)-pyrazolo[3,4-b]quinoline with antiviral effects
    1985, Vol. 50, Issue 9, pp. 2010–2014 [Abstract]
  • Stanislav Rádl, Viktor Zikán and František Šmejkal
    Syntheses of 1, 2, and 9-methyl derivatives of 4,9-dihydro-3-methyl-4-oxo-1H(2H)-pyrazolo[3,4-b]quinoline and their antiviral activity
    1985, Vol. 50, Issue 5, pp. 1057–1063 [Abstract]
  • Antonín Černý, Jiří Křepelka, Viktor Zikán, Drahuše Vlčková, Jaroslav Vachek, Jiří Holubek, Karel Řežábek, Maria Frühaufová, Miroslav Šeda, Jana Chlebounová and Otakar Marhan
    Some 6-substituted 1-[(5R,8S,10R)-8-ergolinyl]-3,3-diethylureas
    1984, Vol. 49, Issue 12, pp. 2828–2836 [Abstract]
  • Antonín Černý, Viktor Zikán, Drahuše Vlčková, Jan Beneš, Jiří Holubek, Karel Řežábek, Marie Aušková and Jiří Křepelka
    (5R,8S,10R)-6-Alkyl-8-ergolinecarboxylic acids and some of their derivatives
    1983, Vol. 48, Issue 5, pp. 1483–1488 [Abstract]
  • Jiří Křepelka, Viktor Zikán, Jiří Holubek and Miroslav Semonský
    Derivatives of 4-aryl-2,3-dihalogeno-1-naphthol
    1980, Vol. 45, Issue 10, pp. 2700–2705 [Abstract]
  • Viktor Zikán, Miroslav Semonský and Bohumil Kakáč
    The synthesis of 6-amino-8-hydroxy-4-oxo-2-(4-pentyloxybenzoyl)-5,7-diazaspiro[2.5]octa-5,7-diene-1-carbox-N-cyclopentylamide
    1979, Vol. 44, Issue 3, pp. 788–791 [Abstract]
  • Emil Svátek, Viktor Zikán and Miroslav Semonský
    Spectral manifestations of strong hydrogen bonds in seven-membered rings of pyrazolecarboxylic acid derivatives
    1979, Vol. 44, Issue 3, pp. 781–787 [Abstract]
  • Viktor Zikán, Miroslav Semonský, Bohumil Kakáč, Jiří Holubek and Karel Řežábek
    Reactions of methyl esters of 3-bromo-4-(4-alkoxyphenyl)-4-oxo-2-butenoic acids with diethyl sodium malonate
    1978, Vol. 43, Issue 7, pp. 1727–1731 [Abstract]
  • Miloslav Ferles, Oldřich Kocián and Stanislav Rádl
    Reduction of some pyridine derivatives with zinc and formic acid
    1978, Vol. 43, Issue 6, pp. 1628–1633 [Abstract]