- ISSN 0010-0765 printed
- ISSN 1212-6950 electronic
Jan Metyš
- Karel Šindelář, Alexandra Šilhánková, Jiří Urban, Jan Metyš, Martin Valchář and Zdeněk Polívka
Antihistamine Substances. Tricyclic Analogues of N-(4,4-Diphenyl-3-butene-1-yl)nipecotic Acid and Some Related Compounds
1994, Vol. 59, Issue 3, pp. 667–674 [Abstract] - Karel Šindelář, Jiří Holoubek, Emil Svátek, Jan Metyš, Hana Blehová and Zdeněk Polívka
Potential antihistaminics: Tricyclic carboxylic acids derived from 6,11-dihydrodibenzo[b,e]thiepine and 4,9-dihydrothieno[2,3-c]-2-benzothiepine
1991, Vol. 56, Issue 11, pp. 2482–2493 [Abstract] - Jiří Jílek, Miroslav Rajšner, Vladimír Valenta, Miloš Borovička, Jiří Holubek, Miroslav Ryska, Emil Svátek, Jan Metyš and Miroslav Protiva
Synthesis of piperidine derivatives as potential analgetic agents
1990, Vol. 55, Issue 7, pp. 1828–1853 [Abstract] - Jiří Jílek, Karel Šindelář, Jaroslava Grimová, Eva Maturová, Jiří Holubek, Emil Svátek, Jiřina Metyšová, Jan Metyš, Marta Hrubantová and Miroslav Protiva
Potential antidepressant and anti-inflammatory agents: 4-(2-Propylthio)acetophenone oximes and 4-(2-propylthio)phenylalkanoic acids
1990, Vol. 55, Issue 5, pp. 1266–1277 [Abstract] - Zdeněk Polívka, Miloš Buděšínský, Jiří Holubek, Bohdan Schneider, Zdeněk Šedivý, Emil Svátek, Oluše Matoušová, Jan Metyš, Martin Valchář, Radomír Souček and Miroslav Protiva
4H-Benzo[4,5]cyclohepta[1,2-b]thiophenes and 9,10-dihydro derivatives - Sulfonium analogues of pizotifen and ketotifen; Chirality of ketotifen; Synthesis of the 2-bromo derivative of ketotifen
1989, Vol. 54, Issue 9, pp. 2443–2469 [Abstract] - Jiří Jílek, Jiří Urban, Vojtěch Kmoníček, Josef Pomykáček, Jiří Holubek, Emil Svátek, Oluše Matoušová, Jan Metyš, Martin Valchář, Stanislav Wildt and Miroslav Protiva
Potential anticonvulsants: 3-Chlorobenzophenone derivatives
1989, Vol. 54, Issue 8, pp. 2248–2260 [Abstract] - Irena Červená, Jiří Holubek, Emil Svátek, Jan Metyš and Miroslav Protiva
Potential antidepressants: 2-(Aminoalkoxy)biphenyls and some related ω-substituted 2-alkoxybiphenyls
1989, Vol. 54, Issue 7, pp. 1966–1978 [Abstract] - Zdeněk Polívka, Vladimír Valenta, Karel Šindelář, Jiří Holubek, Miloš Buděšínský, Miroslav Ryska, Ivan Koruna, Jitka Kohoutová, Jan Metyš, Jiřina Metyšová, Martin Valchář and Miroslav Protiva
Potential antidepressants: Saturated side chain amines derived from 6,11-dihydrodibenzo[b,e]thiepin and 4,9-dihydrothieno[2,3-c]-2-benzothiepin
1989, Vol. 54, Issue 1, pp. 235–247 [Abstract] - Irena Červená, Jiří Holubek, Emil Svátek, Jan Metyš, Martin Valchář and Miroslav Protiva
Potential antidepressants: Synthesis of two 4-(aminoalkoxy)dibenzo[b,e]thiepin-11(6H)-ones
1989, Vol. 54, Issue 1, pp. 225–228 [Abstract] - Zdeněk Polívka, Jan Metyš and Miroslav Protiva
6,11-Dihydrodibenzo[b,e]thiepin-11-yl 3-quinuclidinyl ethers: New potential intidepressants and antihistamine agents
1988, Vol. 53, Issue 8, pp. 1806–1811 [Abstract] - Jiří Jílek, Jiří Holubek, Emil Svátek, Jan Metyš, Hana Frycová, Josef Pomykáček and Miroslav Protiva
Tricyclic analogues of the antiallergic agent oxatomide: 1-(3-(4-(10,11-Dihydro-5H-dibenzo[a,d]cycloheptene-5-yl)-1-piperazinyl)propyl)-1,3-dihydro-2H-benzimidazol-2-one and the related 6,11-dihydrodibenzo[b,e]thiepin, 4,9-dihydrothieno[2,3-c]-2-benzothiepin, and 10,11-dihydrodibenzo[b,f]thiepin derivatives
1988, Vol. 53, Issue 4, pp. 870–883 [Abstract] - Vladimír Valenta, Hana Hulinská, Jiří Holubek, Antonín Dlabač, Jan Metyš, Hana Frycová and Miroslav Protiva
N-substituted derivatives of 6,11-dihydrodibenzo[b,e]thiepin-11-amine and related compounds; Synthesis and pharmacological screening
1988, Vol. 53, Issue 4, pp. 860–869 [Abstract] - Zdeněk Vejdělek, Jan Metyš, Jiří Holubek, Miloš Buděšínský, Emil Svátek, Oluše Matoušová and Miroslav Protiva
Potentional anxiolytics and hypnotics: 1-(Alkanesulfonamidoalkyl)-6-aryl-8-halogeno-s-triazolo[4,3-a]-1,4-benzodiazepines and related compounds
1988, Vol. 53, Issue 1, pp. 132–144 [Abstract] - Zdeněk Polívka, Jiří Holubek, Miloš Buděšínský, Oluše Matoušová, Emil Svátek, Jan Metyš and Miroslav Protiva
Potential antihistamine agents: 4-(6,11-Dihydrodibenzo[b,e]thiepin-11-ylidene)-1-methyltetrahydrothiopyranium iodide and similar sulfonium salts derived from related tricyclic systems
1987, Vol. 52, Issue 11, pp. 2758–2774 [Abstract] - Jiří Urban, Emil Svátek, Miroslav Ryska, Jan Metyš, Stanislav Wildt and Miroslav Protiva
4-Aryl-3-(dimethylaminomethyl)thiacyclohexan-4-ols including the thia analogue of tramadol; Synthesis and analgetic activity
1987, Vol. 52, Issue 5, pp. 1340–1351 [Abstract] - Zdeněk Polívka, Jan Metyš and Miroslav Protiva
Heterocyclic ethers derived from 6,11-dihydrodibenzo[b,e]thiepin-11-ols and 4,9-dihydrothieno[2,3-c]-2-benzothiepin-4-ol; A new series of potential antidepressants and antihistamine agents
1986, Vol. 51, Issue 9, pp. 2034–2049 [Abstract] - Karel Šindelář, Jan Metyš and Miroslav Protiva
Potential antidiarrheal agents: 1-(11-Cyano-6,11-dihydrodibenzo[b,e]thiepin-11-yl-alkyl)- and 1-(10-cyano-10,11-dihydrodibenzo[b,f]thiepin-10-yl-alkyl)-4-substituted piperidines
1985, Vol. 50, Issue 5, pp. 1089–1096 [Abstract] - Zdeněk Polívka, Jiří Holubek, Emil Svátek, Jan Metyš and Miroslav Protiva
Synthesis of the semi-rigid analogues of prothiadene and dithiadene as potential antidepressant and antihistamine agents: 11-[2-(Dimethylaminomethyl)cyclohexylidene]-6,11-dihydrodibenzo[b,e]thiepins and 4-[2-(dimethylaminomethyl)cyclohexylidene]-4,9-dihydrothieno-[2,3-c]-2-benzothiepins
1985, Vol. 50, Issue 5, pp. 1078–1088 [Abstract] - Zdeněk Vejdělek, Jan Metyš, Jiří Holubek, Emil Svátek and Miroslav Protiva
Potential antiparkinsonic agents: Synthesis and pharmacology of some 4-fluoro-4'-halogen'benzhydryl 2-(N,N-disubstituted amino)ethyl ethers
1984, Vol. 49, Issue 11, pp. 2649–2660 [Abstract] - Zdeněk Polívka, Jiří Holubek, Emil Svátek, Jan Metyš and Miroslav Protiva
Potential hypnotics and anxiolytics: Synthesis of 2-bromo-4-(2-chlorophenyl)-9-[4-(2-methoxyethyl)piperazino]-6H-thieno[3,2,4-triazolo[4,3-a]-1,4-diazepine and of some related compounds
1984, Vol. 49, Issue 3, pp. 621–636 [Abstract] - Zdeněk Polívka, Jiří Holubek, Jan Metyš, Zdeněk Šedivý and Miroslav Protiva
Potential hypnotics and anxiolytics: 8-Chloro-6-(2-chlorophenyl)-1-[4-(2-methoxyethyl)piperazino]-methyl-4H-s-triazolo[4,3-a]-1,4-benzodiazepine and related compounds
1983, Vol. 48, Issue 12, pp. 3433–3443 [Abstract] - Zdeněk Polívka, Miroslav Ryska, Jiří Holubek, Emil Svátek, Jan Metyš and Miroslav Protiva
Potential hypnotics and anxiolytics in the 4H-s-triazolo[4,3-a]-1,4-benzodiazepine series: 8-Chloro-6-(2-chlorophenyl)-1-[4-(2-methoxyethyl)piperazino]-4H-s-triazolo[4,3-a]-1,4-benzodiazepine and some related compounds
1983, Vol. 48, Issue 8, pp. 2395–2410 [Abstract] - Zdeněk Polívka, Miroslav Rajšner, Jan Metyš, Jiří Holubek, Emil Svátek, Miroslav Ryska and Miroslav Protiva
Antiaminic agents derived from thieno[2,3-c]-2-benzothiepin: 4-(1-Methyl-4-piperidylidene)-4,9-dihydrothieno[2,3-c]-2-benzothiepin and some related compounds
1983, Vol. 48, Issue 2, pp. 623–641 [Abstract] - Miroslav Rajšner, Jan Metyš, Jiří Holubek and Miroslav Protiva
Potential antidepressants: Some N-substituted derivatives of (E)-11-(3-methylaminopropylidene)-6,11-dihydrodibenzo[b,e]thiepin
1983, Vol. 48, Issue 1, pp. 163–172 [Abstract] - Zdeněk J. Vejdělek, Jan Metyš and Miroslav Protiva
S-Substituted derivatives of 8-chloro-6-(2-chlorophenyl)-1-mercaptomethyl-4H-s-triazolo[4,3-a]-1,4-benzodiazepine; Synthesis and pharmacology
1983, Vol. 48, Issue 1, pp. 123–136 [Abstract] - Vladimír Valenta, Jan Metyš and Miroslav Protiva
(6,11-Dihydrodibenzo[b,e]thiepin-11-yl)methylamine, (4-methoxy-6,11-dihydrodibenzo[b,e]thiepin-11-yl)-methylamine and derivatives; Synthesis and pharmacological screening
1982, Vol. 47, Issue 3, pp. 984–993 [Abstract] - Miroslav Rajšner, Emil Svátek, Jan Metyš and Miroslav Protiva
Antidepressant fluorinated prothiadene derivatives: 9-Fluoro and 2,9-difluoro derivative of 11-(3-dimethylaminopropylidene)-6,11-dihydrodibenzo[b,e]thiepin
1982, Vol. 47, Issue 1, pp. 65–71 [Abstract] - Karel Šindelář, Jiří Holubek, Jan Metyš, Marie Bartošová and Miroslav Protiva
Synthesis of 3-(2-alkoxyphenoxy)-2-methyl (or phenyl)propylamines as potential antidepressants
1981, Vol. 46, Issue 3, pp. 597–606 [Abstract] - Zdeněk Vejdělek, Emil Svátek, Jiří Holubek, Jan Metyš, Marie Bartošová and Miroslav Protiva
Synthesis and pharmacological screening of 1-[2-tert-aminoethyl]-8-fluoro-5-[4-fluorophenyl]-2,3,4,5-tetrahydro-1H-1-benzazepines, their 1-[aminoacetyl] analogues and 1-substituted 9-fluoro-6-[4-fluorophenyl]-5,6-dihydro-4H-s-triazolo[4,3-a]-1-benzazepines
1981, Vol. 46, Issue 1, pp. 148–160 [Abstract] - Vladimír Valenta, Jiří Jílek, Josef Pomykáček, Antonín Dlabač, Martin Valchář, Jan Metyš and Miroslav Protiva
Noncataleptic potential neuroleptics: 2-Methyl-10-(4-methylpiperazino)- and -10-[4-(2-hydroxyethyl)piperazino]-10,11-dihydrodibenzo[b,f]thiepin
1979, Vol. 44, Issue 9, pp. 2677–2688 [Abstract] - Miroslav Rajšner, Václav Bártl, Karel Šindelář, Emil Svátek, Jiří Holubek, Jan Metyš and Miroslav Protiva
Synthesis of new dibenzo[b,e]thiepin derivatives related to the antidepressant agent prothiadene
1979, Vol. 44, Issue 8, pp. 2536–2549 [Abstract] - Miroslav Rajšner, Zdeňka Kopicová, Jiří Holubek, Emil Svátek, Jan Metyš, Marie Bartošová, František Mikšík and Miroslav Protiva
4,4-Bis(4-fluorophenyl)butylamines and their cyclic analogues; An efficient synthesis of the neuroleptic penfluridol
1978, Vol. 43, Issue 7, pp. 1760–1777 [Abstract]
The following name might also represent this author:
J. Metyš
- Z. J. Vejdělek, J. Metyš, J. Němec and M. Protiva
Potential tranquilizing agents: 1-(4-Aminosulfonylphenacyl)-4-methyl(and phenyl)piperazines
1975, Vol. 40, Issue 12, pp. 3895–3903 [Abstract] - M. Rajšner, J. Metyš, B. Kakáč and M. Protiva
Tricyclic systems containing a 3-thienylsulfide fragment; 10-(3-Dimethylaminopropylidene)-5,10-dihydrothieno[3,2-c]-2-benzothiepin, a new effective antihistamine
1975, Vol. 40, Issue 9, pp. 2905–2911 [Abstract] - Z. J. Vejdělek, J. Metyš, F. Hradil and M. Protiva
1-(4-Alkanesulfonylphenacyl)-4-arylpiperazines and related compounds: A new series of central depressants
1975, Vol. 40, Issue 4, pp. 1204–1217 [Abstract] - M. Rajšner, E. Svátek, J. Metyš and M. Protiva
Geometric isomerism of 4-(3-dimethylaminopropylidene)-9H-thieno[2,3-b]benzo[e]thiepin
1974, Vol. 39, Issue 5, pp. 1366–1376 [Abstract] - V. Bártl, J. Metyšová, J. Metyš, J. Němec and M. Protiva
Neurotropic and psychotropic agents. LXIII. 7-Methoxy-10-(4-methylpiperazino)dibenzo[b,f]thiepin and its 10,11-dihydro derivative
1973, Vol. 38, Issue 8, pp. 2301–2306 [Abstract] - Z. J. Vejdělek, F. Hradil, J. Metyš and M. Protiva
Benzocycloheptenes and heterocyclic analogues as potential drugs. V. 2-(2-Aminoethyl)-6,7,8,9-tetrahydro-5H-benzocycloheptene and derivatives
1972, Vol. 37, Issue 9, pp. 3136–3143 [Abstract] - V. Seidlová, L. Novák, J. O. Jílek, J. Metyš and M. Protiva
Antihistamine substances. LIII. ortho-Substituted derivatives of 1,1-diphenyl-1-(2-dimethylaminoethoxy)ethane
1971, Vol. 36, Issue 1, pp. 299–303 [Abstract] - J. O. Jílek, K. Šindelář, J. Metyšová, J. Metyš, J. Pomykáček and M. Protiva
Neurotropic and psychotropic substances. XLIV. 10-(Aminoalkoxy) and 10-piperazino derivatives of dibenzo[b,f]thiepin and related systems
1970, Vol. 35, Issue 12, pp. 3721–3732 [Abstract] - K. Šindelář, E. Svátek, J. Metyšová, J. Metyš and M. Protiva
Neurotropic and psychotropic substances. XXXVII. Derivatives of selenoxanthene
1969, Vol. 34, Issue 12, pp. 3792–3800 [Abstract] - M. Rajšner, J. Metyš, E. Svátek and M. Protiva
Neurotropic and psychotropic compounds. XXXI. Chemistry and pharmacology of 11-(3-dimethylaminopropylidene)-2-methyl-6,11-dihydrodibenzo[b,e]thiepin and of some analogues
1969, Vol. 34, Issue 3, pp. 1015–1024 [Abstract] - I. Jirkovský, J. Metyš and M. Protiva
Neurotrope und psychotrope Substanzen XVIII. Zwei neue 6,11-Dihydrodibenz[b,e]oxepin-Derivate
1967, Vol. 32, Issue 9, pp. 3448–3451 [Abstract] - M. Rajšner, J. Metyš and M. Protiva
Neurotrope und psychotrope Substanzen XV. 4,9-Dihydrothieno[2,3-b]benzo[e]thiepin-Derivate
1967, Vol. 32, Issue 8, pp. 2854–2866 [Abstract] - J. O. Jílek, J. Pomykáček, J. Metyšová, J. Metyš and M. Protiva
Neurotrope und psychotrope Substanzen III. Derivate des Dibenz(b,f)(1,4)oxazepins
1965, Vol. 30, Issue 2, pp. 463–471 [Abstract]