Collect. Czech. Chem. Commun. 2001, 66, 959-972
https://doi.org/10.1135/cccc20010959

Isolation of DT-Diaphorase [NAD(P)H Dehydrogenase (Quinone)] from Rat Liver Cytosol: Identification of New Enzyme Substrates, Carcinogenic Aristolochic Acids

Marie Stiborováa,*, Miroslav Hájeka, Hana Vošmikováa, Eva Freib and Heinz H. Schmeiserb

a Department of Biochemistry, Charles University, Albertov 2030, 128 40 Prague 2, Czech Republic
b Department of Molecular Toxicology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany

Individual author index pages


Other CCCC articles of these authors

  • Miroslav Hájek, Naděžda Matulová, Ivan Votruba, Antonín Holý and Eva Tloušťová
    Acyclic nucleoside phosphonates and human telomerase inhibition
    Symposium Series 2005, Vol. 7, pp. 373–374 [Abstract]
    Published online 2015-11-08 11:55:35
  • Karel Naiman, Petr Hodek, Jiří Liberda, Heinz H. Schmeiser, Eva Frei and Marie Stiborová*
    Rat liver microsomal metabolism of o-aminophenol and N-(2-methoxyphenyl)hydroxylamine, two metabolites of the environmental pollutant and carcinogen o-anisidine in humans
    2010, Vol. 75, Issue 12, pp. 1229–1247 [Abstract]
  • Martina Svobodová, Markéta Martínková, Eva Frei and Marie Stiborová*
    Identification of human enzymes oxidizing a human metabolite of carcinogenic 2-nitroanisole, 2-nitrophenol. Evidence for its oxidative detoxification by human cytochromes P450
    2010, Vol. 75, Issue 6, pp. 703–719 [Abstract]
  • Lucie Bořek-Dohalská and Marie Stiborová*
    Cytochrome P450 3A activities and their modulation by α-naphthoflavone in vitro are dictated by the efficiencies of model experimental systems
    2010, Vol. 75, Issue 2, pp. 201–220 [Abstract]
  • Marie Stiborová*, Helena Dračínská, Dagmar Aimová, Petr Hodek, Jiří Hudeček, Helena Ryšlavá, Heinz H. Schmeiser and Eva Frei
    The Anticancer Drug Ellipticine is an Inducer of Rat NAD(P)H:Quinone Oxidoreductase
    2007, Vol. 72, Issue 10, pp. 1350–1364 [Abstract]
  • Jitka Poljaková, Martin Dračínský, Eva Frei, Jiří Hudeček and Marie Stiborová*
    The Effect of pH on Peroxidase-Mediated Oxidation of and DNA Adduct Formation by Ellipticine
    2006, Vol. 71, Issue 8, pp. 1169–1185 [Abstract]
  • Petr Hodek*, Tomáš Koblas, Helena Rýdlová, Božena Kubíčková, Miroslav Šulc, Jiří Hudeček and Marie Stiborová
    Chicken Egg Yolk as an Excellent Source of Highly Specific Antibodies Against Cytochromes P450
    2004, Vol. 69, Issue 3, pp. 659–673 [Abstract]
  • Lucie Bořek-Dohalská, Eva Frei and Marie Stiborová*
    DNA Adduct Formation by the Anticancer Drug Ellipticine and Its Hydroxy Derivatives in Human Breast Adenocarcinoma MCF-7 Cells
    2004, Vol. 69, Issue 3, pp. 603–615 [Abstract]
  • Markéta Mikšanová, Petr Novák, Eva Frei and Marie Stiborová*
    Metabolism of Carcinogenic 2-Nitroanisole in Rat, Rabbit, Porcine and Human Hepatic Cytosol
    2004, Vol. 69, Issue 3, pp. 589–602 [Abstract]
  • Marie Stiborová*, Martina Rupertová, Petr Hodek, Eva Frei and Heinz H. Schmeiser
    Monitoring of DNA Adducts in Humans and 32P-Postlabelling Methods. A Review
    2004, Vol. 69, Issue 3, pp. 476–498 [Abstract]
  • Václav Martínek and Marie Stiborová*
    Metabolism of Carcinogenic Azo Dye Sudan I by Rat, Rabbit, Minipig and Human Hepatic Microsomes
    2002, Vol. 67, Issue 12, pp. 1883–1898 [Abstract]
  • Markéta Mikšanová, Jiří Hudeček, Jan Páca and Marie Stiborová*
    To the Mechanism of Horseradish Peroxidase-Mediated Degradation of a Recalcitrant Dye Remazol Brilliant Blue R
    2001, Vol. 66, Issue 4, pp. 663–675 [Abstract]
  • Marie Stiborová*, Markéta Mikšanová, Václav Martínek and Eva Frei
    Heme Peroxidases: Structure, Function, Mechanism and Involvement in Activation of Carcinogens. A Review
    2000, Vol. 65, Issue 3, pp. 297–325 [Abstract]
  • Lucie Bořek-Dohalská*, Petr Hodek and Marie Stiborová
    New Selective Inhibitors of Cytochrome P450 2B4 and an Activator of Cytochrome P450 3A6 in Rabbit Liver Microsomes
    2000, Vol. 65, Issue 1, pp. 122–132 [Abstract]
  • Marie Stiborová*, Heinz H. Schmeiser, Andrea Breuer and Eva Frei
    32P-Postlabelling Analysis of DNA Adducts with 1-(Phenylazo)-2-naphthol (Sudan I, Solvent Yellow 14) Formed in vivo in Fisher 344 Rats
    1999, Vol. 64, Issue 8, pp. 1335–1347 [Abstract]
  • Marie Stiborová, Heinz H. Schmeiser and Eva Frei
    To the Mechanism of 2-Nitroanisole Carcinogenicity: in vitro Metabolism of 2-Nitroanisole Mediated by Peroxidasesand Xanthine Oxidase
    1998, Vol. 63, Issue 6, pp. 857–869 [Abstract]
  • Marie Stiborová and Hana Hansíková
    Peroxidases from Tulip Bulbs (Tulipa fosteriana, L.) Oxidize Xenobiotics NNitrosodimethylamine and N-Nitroso-N-methylaniline in vitro
    1997, Vol. 62, Issue 11, pp. 1804–1814 [Abstract]
  • Marie Stiborová, Eva Frei and Heinz H. Schmeiser
    Study on N-Demethylation of N,N-Dimethyl-4-aminoazobenzene and N-Nitrosamines by Prostaglandin H Synthase
    1997, Vol. 62, Issue 6, pp. 971–980 [Abstract]
  • Marie Stiborová and Hana Hansíková
    Cytochrome P-450 from Tulip Bulbs (Tulipa fosteriana L.) Oxidizes an Azo Dye Sudan I (1-Phenylazo-2-hydroxynaphthalene, Solvent Yellow 14) in vitro
    1996, Vol. 61, Issue 11, pp. 1689–1696 [Abstract]
  • Marie Stiborová, Befekadu Asfaw, Eva Frei and Heinz H. Schmeiser
    Oxidation of Azo Dyes by Peroxidase: Additional Evidence of a One-Electron Mechanism of Oxidation of Dimethylaminoazobenzene and Sudan I (Solvent Yellow 14)
    1996, Vol. 61, Issue 6, pp. 962–972 [Abstract]
  • Marie Stiborová, Eva Frei, Heinz H. Schmeiser and Manfred Wiessler
    Cytochrome P-450 and Peroxidase Oxidize Detoxication Products of Carcinogenic Aristolochic Acids (Aristolactams) to Reactive Metabolites Binding to DNA in vitro
    1995, Vol. 60, Issue 12, pp. 2189–2199 [Abstract]
  • Marie Stiborová, Befekadu Asfaw, Eva Frei, Heinz H. Schmeiser and Manfred Wiessler
    Identification of 1-(3,4-Dihydroxyphenylazo)-2-hydroxynaphthalene as the Product of Oxidation of 1-Phenylazo-2-hydroxynaphthalene (Sudan I, Solvent Yellow 14) by Rat Liver Microsomes
    1994, Vol. 59, Issue 12, pp. 2727–2733 [Abstract]
  • Marie Stiborová and Pavel Anzenbacher
    Carcinogenic Non-Aminoazo Dye 1-Phenylazo-2-hydroxynaphthalene (Sudan I) Is Oxidized by Rat Liver Microsomal Cytochrome P-450 to Metabolites Binding to Macromolecules (Nucleic Acids and Proteins)
    1992, Vol. 57, Issue 7, pp. 1537–1546 [Abstract]
  • Marie Stiborová and Pavel Anzenbacher
    NADH oxidation during peroxidase catalyzed metabolism of carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxynaphthalene (Sudan I)
    1990, Vol. 55, Issue 9, pp. 2321–2327 [Abstract]
  • Marie Stiborová, Befekadu Asfaw and Pavel Anzenbacher
    Ce(IV)-mediated formation of benzenediazonium ion from a non-aminoazo dye, 1-phenylazo-2-hydroxy-naphthalene (Sudan I) and its binding to DNA
    1989, Vol. 54, Issue 7, pp. 2021–2026 [Abstract]
  • Marie Stiborová, Světlana Kšinská and Sylva Leblová
    Mechanism of action of NaCl on maize alcohol dehydrogenase and phosphoenolpyruvate carboxylase
    1987, Vol. 52, Issue 12, pp. 3024–3033 [Abstract]
  • Marie Stiborová and Sylva Leblová
    Effect of heterocyclic compounds and 2-mercaptoethanol on rape alcohol dehydrogenase
    1987, Vol. 52, Issue 8, pp. 2107–2113 [Abstract]
  • Marie Stiborová, Marta Doubravová, Alena Březinová and Aleš Friedrich
    Effect of heavy metal ions on barley ribulose-1,5-bisphosphate carboxylase
    1987, Vol. 52, Issue 2, pp. 525–534 [Abstract]
  • Marie Stiborová and Sylva Leblová
    Mechanism of action of heavy metals, S-triazine herbicides and nitrates on alcohol dehydrogenase from rape
    1986, Vol. 51, Issue 8, pp. 1781–1788 [Abstract]
  • Marie Stiborová and Sylva Leblová
    Iodoacetate inactivation of rape alcohol dehydrogenase
    1980, Vol. 45, Issue 5, pp. 1601–1607 [Abstract]
  • Sylva Leblová, Noemi Nováková and Marie Stiborová
    Effect of metal ions on pea alcohol dehydrogenase
    1979, Vol. 44, Issue 3, pp. 799–803 [Abstract]
  • Marie Stiborová, Roman Lapka, Noemi Nováková and Sylva Leblová
    Pea alcohol dehydrogenase: Substrate specificity and binding of coenzyme to enzyme
    1979, Vol. 44, Issue 2, pp. 631–636 [Abstract]
  • Marie Stiborová and Sylva Leblová
    Studies on binding site of alcohol dehydrogenase from rape seedlings
    1978, Vol. 43, Issue 8, pp. 2217–2223 [Abstract]