Collect. Czech. Chem. Commun.
2000, 65, 1082-1092
https://doi.org/10.1135/cccc20001082
Synthesis and Biological Evaluation of New Antiinflammatory 1-Benzothiophene-2-carboxanilides
Jiří Svobodaa,*, Michal Štádlera, Antonín Janderab, Vladimíra Panajotováb and Miroslav Kuchařb
a Department of Organic Chemistry, Prague Institute of Chemical Technology, 166 28 Prague 6, Czech Republic
b Research Institute for Pharmacy and Biochemistry, 130 60 Prague 3, Czech Republic
Individual author index pages
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- Aleš Machara, Václav Kozmík, Michaela Pojarová, Hana Dvořáková and Jiří Svoboda*
Preparation and rearrangement study of novel thiophenium- and selenophenium-ylides
2009, Vol. 74, Issue 5, pp. 785–798 [Abstract] - Aleš Machara, Michaela Pojarová and Jiří Svoboda*
Synthesis and Cycloaddition Reaction of 3-Vinylthieno[3,2-b][1]benzothiophene
2007, Vol. 72, Issue 7, pp. 952–964 [Abstract] - Václav Kozmík, Bedřich Košata, Jiří Svoboda* and Miroslav Kuchař
A Study of 5-Nitroindole Alkylation
2006, Vol. 71, Issue 5, pp. 679–690 [Abstract] - Miroslav Kuchař*, Bohumila Brunová, Richard Junek, Robert Rodling, Josef Hájíček, Vladimíra Panajotová and Antonín Jandera
The Antileukotrienic Derivatives and Homologues of [(Quinolin-2-ylmethoxy)sulfanyl]benzoic Acids with Reduced Lipophilicity
2005, Vol. 70, Issue 9, pp. 1357–1371 [Abstract] - Miroslav Kuchař*, Vojtěch Kmoníček, Vladimíra Panajotová, Antonín Jandera, Bohumila Brunová, Richard Junek, Věra Bucharová, Jan Čejka and Dalibor Šatinský
Derivatives of (Phenylsulfanyl)benzoic Acids with Multiple Antileukotrienic Activity
2004, Vol. 69, Issue 11, pp. 2098–2120 [Abstract] - Vladimír Wsól*, Barbora Szotáková, Vendula Baliharová, Luděk Šišpera, Michal Holčapek, Lenka Kolářová, Bohumila Suchanová, Miroslav Kuchař and Lenka Skálová
The Phase I Biotransformation of the Potential Antileukotrienic Drug Quinlukast in Rat Microsomes and Hepatocytes
2004, Vol. 69, Issue 3, pp. 689–702 [Abstract] - Michal Rejňák, Jiří Klíma, Jiří Svoboda and Jiří Ludvík*
Synthesis and Electrochemical Reduction of Methyl 3-Halo-1-benzothiophene-2-carboxylates
2004, Vol. 69, Issue 1, pp. 242–260 [Abstract] - Marie Mézlová, Hana Petříčková, Petr Maloň, Václav Kozmík and Jiří Svoboda*
Axially Chiral 3,3'-Bi(1-benzothiophene)-2,2'-dicarboxylic Acid and Its Derivatives
2003, Vol. 68, Issue 5, pp. 1020–1038 [Abstract] - Bedřich Košata, Václav Kozmík and Jiří Svoboda*
Reactivity of [1]Benzothieno[3,2-b][1]benzothiophene - Electrophilic and Metallation Reactions
2002, Vol. 67, Issue 5, pp. 645–664 [Abstract] - Kateřina Černovská, Miloslav Nič, Pavel Pihera and Jiří Svoboda*
A Novel Synthesis of [1]Benzothieno[3,2-b][1]benzofuran
2000, Vol. 65, Issue 12, pp. 1939–1949 [Abstract] - Pavel Pihera and Jiří Svoboda*
Reactivity Studies of [1]Benzothieno[3,2-b][1]benzofuran
2000, Vol. 65, Issue 1, pp. 58–76 [Abstract] - Pavel Pihera, Hana Dvořáková and Jiří Svoboda*
Diels-Alder Reactions of Vinyl Derivatives of [1]Benzothieno[3,2-b]furan
1999, Vol. 64, Issue 2, pp. 389–407 [Abstract] - Pavel Pihera, Jaroslav Paleček and Jiří Svoboda
Diels-Alder Reactions of [1]Benzothieno[3,2-b]furan
1998, Vol. 63, Issue 5, pp. 681–697 [Abstract] - Miroslav Kuchař, Kateřina Čulíková, Vladimíra Panajotovová, Bohumila Brunová, Antonín Jandera and Vojtěch Kmoníček
2,4-Dihydroxyacetophenone Derivatives as Antileukotrienics with a Multiple Activity Mechanism
1998, Vol. 63, Issue 1, pp. 103–114 [Abstract] - Petr Váchal, Pavel Pihera and Jiří Svoboda
Thieno[3,2-b]benzofuran - Synthesis and Reactions
1997, Vol. 62, Issue 9, pp. 1468–1480 [Abstract] - Miroslav Kuchař, Marie Poppová, Antonín Jandera, Vladimíra Panajotovová, Hana Zůnová, Miloš Buděšínský, Hana Tomková, Alexandr Jegorov and Jan Taimr
Chiral Forms of 4-(2',4'-Difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic Acid (Flobufen) and Its Metabolite.Synthesis and Basic Biological Properties
1997, Vol. 62, Issue 3, pp. 498–509 [Abstract] - Jiří Svoboda, Václav Kozmík, Ivan Veselý and Jaroslav Paleček
New Synthesis of Important Prostanoid Intermediate
1996, Vol. 61, Issue 10, pp. 1509–1519 [Abstract] - Jiří Svoboda, Pavel Pihera, Petr Sedmera and Jaroslav Paleček
Electrophilic Substitution Reactions of [1]Benzothieno[3,2-b]furan
1996, Vol. 61, Issue 6, pp. 888–900 [Abstract] - Jiří Svoboda and Jaroslav Paleček
New Method for Preparation of 1-Azabicyclo[2.2.2]octane-4-carbonitrile and 1-Azabicyclo[3.2.2]nonane-5-carbonitrile
1995, Vol. 60, Issue 9, pp. 1536–1540 [Abstract] - Miroslav Kuchař, Václav Vosátka, Marie Poppová, Eva Knězová, Vladimíra Panajotovová, Hana Tomková and Jan Taimr
Some Analogs of 4-(2',4'-Difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic Acid: Synthesis and Antiinflammatory Activity
1995, Vol. 60, Issue 6, pp. 1026–1033 [Abstract] - Miroslav Kuchař, Marie Poppová, Hana Zůnová, Eva Knězová, Václav Vosátka and Marek Příhoda
4-(2',4'-Difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic Acid and Its Derivatives
1994, Vol. 59, Issue 12, pp. 2705–2713 [Abstract] - Jiří Svoboda, Miloslav Nič and Jaroslav Paleček
Synthesis of [1]Benzothieno[3,2-b]furan - A New Fused Benzoheterocyclic System
1993, Vol. 58, Issue 12, pp. 2983–2986 [Abstract] - Jiří Svoboda, Miloslav Nič and Jaroslav Paleček
Application of Magnesium Alkoxides to Syntheses of Benzoheterocyclic Compounds
1993, Vol. 58, Issue 3, pp. 592–599 [Abstract] - Jiří Svoboda, Miloslav Nič and Jaroslav Paleček
An Anomalous Course of the Darzens Reaction Catalyzed with Magnesium Methoxide
1992, Vol. 57, Issue 1, pp. 119–122 [Abstract] - Jiří Svoboda and Jaroslav Paleček
Synthesis of N-[(3-substituted phenoxy)alkyl]acetohydroxamic acids, potential inhibitors of the enzyme 5-lipoxygenase
1991, Vol. 56, Issue 6, pp. 1317–1332 [Abstract] - Bohdan Schneider, Václav Rejholec and Miroslav Kuchař
Three-dimensional structures of substituted diphenyl sulfides
1990, Vol. 55, Issue 11, pp. 2590–2601 [Abstract] - Miloš Beran, Antonín Černý, Miroslav Kuchař, Hana Adamírová, Jiří Holubek, Jan Taimr, Jaroslav Vachek, Maria Frühaufová, Karel Řežábek, Martin Valchář and Ivan Krejčí
9,10-Dihydroergopeptines modified in position 6
1990, Vol. 55, Issue 3, pp. 819–832 [Abstract] - Miroslav Kuchař, Jaroslava Grimová, Václav Rejholec, Hana Tomková, Magda Jelínková and Jiří Holubek
Use of QSAR in design of antiinflammatory fluorinated arylalkanoic acids
1990, Vol. 55, Issue 1, pp. 296–306 [Abstract] - Miroslav Kuchař, Eva Maturová, Bohumila Brunová, Jaroslava Grimová, Hana Tomková and Jiří Holubek
Quantitative relations between structure and antiinflammatory activity of aryloxoalkanoic acids
1988, Vol. 53, Issue 8, pp. 1862–1872 [Abstract] - Jiří Svoboda, Zuzana Kocfeldová and Jaroslav Paleček
Reaction of 4-substituted benzaldehydes and acetophenones with chloroacetonitrile
1988, Vol. 53, Issue 4, pp. 822–832 [Abstract] - Jiří Svoboda, Karel Čapek and Jaroslav Paleček
Esters of arylpropionic acids with 1,2:5,6-di-O-isopropylidene- and 1,2-O-isopropylidene-α-D-glucofuranose
1987, Vol. 52, Issue 3, pp. 766–774 [Abstract] - Miroslav Kuchař, Bohumila Brunová, Jaroslava Grimová, Stanislav Vaněček and Jiří Holubek
Synthesis of cyclohexylaliphatic acids and their pharmacological properties
1986, Vol. 51, Issue 12, pp. 2896–2908 [Abstract] - Miroslav Kuchař, Bohumila Brunová, Jaroslava Grimová, Václav Rejholec and Václav Čepelák
On the quantitative relations between structure and antiaggregation activity of ω-aryl-ω-oxoalkanoic acids
1986, Vol. 51, Issue 11, pp. 2617–2625 [Abstract] - Jiří Svoboda, Jaroslav Paleček and Václav Dědek
Phase transfer catalysed N-substitution of 2H-1,2-benzisothiazolin-3-one 1,1-dioxide
1986, Vol. 51, Issue 6, pp. 1304–1310 [Abstract] - Jiří Svoboda, Jaroslav Paleček and Václav Dědek
The synthesis of substituted 2H-1,2-benzothiazines 1,1-dioxides
1986, Vol. 51, Issue 5, pp. 1133–1139 [Abstract] - Jiří Svoboda, Jaroslav Paleček, Václav Dědek and Jiří Mostecký
One-step synthesis of substituted 2-aryl-2-bromoalkyl-1,3-dioxolanes
1984, Vol. 49, Issue 6, pp. 1515–1520 [Abstract] - Miroslav Kuchař, Bohumila Brunová, Václav Rejholc, Magda Jelínková, Jiří Holubek and Oldřich Němeček
Quantitative relations between structure and activation of fibrinolysis in selected series of arylaliphatic acids
1984, Vol. 49, Issue 1, pp. 122–136 [Abstract] - Miroslav Kuchař, Václav Rejholec, Zdeněk Roubal and Oluše Matoušová
The effects of lipophilicity on the inhibition of denaturation of serum albumin and on the activation of fibrinolysis observed with a series of benzyloxyarylaliphatic acids
1983, Vol. 48, Issue 4, pp. 1077–1088 [Abstract] - Jiří Svoboda, Oldřich Paleta and Václav Dědek
Synthetic transformations of dimethyl perfluoro-4-methyl-2-pentenedioate
1982, Vol. 47, Issue 12, pp. 3418–3423 [Abstract] - Miroslav Kuchař, Václav Rejholec, Bohumila Brunová, Jaroslava Grimová, Oluše Matoušová, Oldřich Němeček and Hana Čepeláková
Benzyloxyarylaliphatic acids: Synthesis and quantitative relations between structure and antiinflammatory activity
1982, Vol. 47, Issue 9, pp. 2514–2524 [Abstract] - Oldřich Paleta, Jiří Svoboda and Václav Dědek
Anionic cis-trans isomerization of dialkyl perfluoro(4-methyl-2-pentene)dioates. A non-classical equilibrium dependence
1982, Vol. 47, Issue 1, pp. 54–58 [Abstract] - Jiří Svoboda, Oldřich Paleta and Václav Dědek
Derivatives of 2,3-difluoro-2-butenedioic acid and their isomerization reactions
1981, Vol. 46, Issue 6, pp. 1495–1503 [Abstract] - Jiří Svoboda, Oldřich Paleta, František Liška and Václav Dědek
Fluorinated 3-diethylaminopropenoates and their reactions
1981, Vol. 46, Issue 6, pp. 1389–1396 [Abstract] - Jiří Svoboda, Oldřich Paleta and Václav Dědek
Reaction of chlorodifluoropropenoates with potassium fluoride
1981, Vol. 46, Issue 5, pp. 1272–1279 [Abstract] - Miroslav Kuchař, Bohumila Brunová, Václav Rejholec, Zdeněk Roubal and Oldřich Němeček
The synthesis of arylpropionic acids and the quantitative relationship between the structure and the activation of fibrinolysis
1981, Vol. 46, Issue 5, pp. 1173–1187 [Abstract] - Oldřich Paleta, Jiří Svoboda, Václav Havlů and Václav Dědek
Anionic cis-trans isomerisation of dimethyl perfluoro-(4-methyl-2-pentene)dioate
1980, Vol. 45, Issue 12, pp. 3360–3369 [Abstract] - Miroslav Kuchař, Bohumila Brunová, Zdeněk Roubal, Jiří Schlanger and Oldřich Němeček
Synthesis of arylacetic acids and their effect on activation of fibrinolysis. Quantitative relations between structure and biological activity
1980, Vol. 45, Issue 5, pp. 1401–1409 [Abstract] - Jiří Svoboda, Oldřich Paleta and Václav Dědek
Ionic dimerisation of trifluoropropenenitrile and its addition reactions with methyl trifluoropropenoate
1980, Vol. 45, Issue 2, pp. 406–414 [Abstract] - Miroslav Kuchař, Václav Rejholec, Zdeněk Roubal and Oldřich Němeček
Quantitative relationships between structure and fibrinolytic activity in the series of α-methyl-β-arylpropionic acids
1979, Vol. 44, Issue 1, pp. 183–193 [Abstract] - Oldřich Paleta, Jiří Svoboda and Václav Dědek
UV-light induced cycloaddition of 3,4-dichloro-3,4,4-trifluoro-2-butanone to 2-methyl-2-butene
1978, Vol. 43, Issue 11, pp. 2932–2941 [Abstract]