Collect. Czech. Chem. Commun. 1989, 54, 2502-2512

Synthesis, molecular conformation and biological activity of 6-amino-5-azacytidine

Alois Pískala, Naeem B. Hanna, Jaroslav Zajíček and Alois Čihák

Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6

Individual author index pages

Other CCCC articles of these authors

  • Alois Pískala, Naeem B. Hanna, Milena Masojídková, Miroslav Otmar and Pavel Fiedler
    Synthesis of N4-alkyl-5-azacytidines and their base pairing with carbamoylguanidines – a contribution to explanation of the mutagenicity of 5-aza-2'-deoxycytidine
    Symposium Series 1999, Vol. 2, pp. 248–251 [Abstract]
    Published online 2016-05-08 23:31:28
  • Marcela Krečmerová, Antonín Holý, Alois Pískala, Graciela Andrei, Robert Snoeck, Jan Balzarini and Erik De Clercq
    New antiviral agent, 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: esters and base-modified derivatives
    Symposium Series 2008, Vol. 10, pp. 196–200 [Abstract]
    Published online 2015-10-30 18:37:33
  • Alois Pískala*, Naeem B. Hanna, Milena Masojídková, Pavel Fiedler and Ivan Votruba
    Synthesis of N4-Amino and N4-Hydroxy Derivatives of 5-Azacytidine. A Facile Rearrangement of the N4-Amino Derivative to 5-(3-β-D-Ribofuranosylureido)-1H-1,2,4-triazole
    2004, Vol. 69, Issue 4, pp. 905–917 [Abstract]
  • Alois Pískala*, Naeem B. Hanna, Milena Masojídková, Miroslav Otmar, Pavel Fiedler and Karel Ubik
    Synthesis of N4-Alkyl-5-azacytidines and Their Base-Pairing with Carbamoylguanidines - A Contribution to Explanation of the Mutagenicity of 2'-Deoxy-5-azacytidine
    2003, Vol. 68, Issue 4, pp. 711–743 [Abstract]
  • Naeem B. Hanna, Milena Masojídková and Alois Pískala
    Synthesis and Biological Activity of N4-Methyl-5-azacytidines
    1998, Vol. 63, Issue 5, pp. 713–722 [Abstract]
  • Naeem B. Hanna, Milena Masojídková, Pavel Fiedler and Alois Pískala
    Synthesis of Some 6-Substituted 5-Azacytidines
    1998, Vol. 63, Issue 2, pp. 222–230 [Abstract]
  • Jaroslav Zajíček, Ivan Rosenberg, Radek Liboska, Zdeněk Točík, G. Victor Fazakerley, Wilhelm Guschlbauer and Antonín Holý
    Conformational Studies on Diribonucleoside Monophosphate Analogs Containing a Nonisosteric, Isopolar, Phosphonate-Based Internucleotide Linkage
    1997, Vol. 62, Issue 1, pp. 83–98 [Abstract]
  • Alois Pískala, Milena Masojídková and David Šaman
    Preparation of some derivatives of 5-azacytidine and 2'-deoxy-5-azacytidine
    1996, Vol. 61, Special Issue, pp. S23–S25 [Abstract]
  • Ladislav Novotný, Anna Vachálková and Alois Pískala
    Investigation of the Polarographic Properties and Potential Carcinogenity of Some Hydroxyurea Derivatives by DC Polarography
    1996, Vol. 61, Issue 4, pp. 656–662 [Abstract]
  • Ladislav Novotný, Anna Vachálková and Alois Pískala
    Polarographic Reduction and Potential Carcinogenity of Substituted 1,3,5-Triazine Nucleosides
    1995, Vol. 60, Issue 9, pp. 1469–1475 [Abstract]
  • Jaroslav Zajíček, Jeffrey F. Ellena, Gerald D. Williams, Mohammad A. Khadim and Michael F. Brown
    Molecular Dynamics of Vesicles of Unsaturated Phosphatidylcholines Studied by 13C NMR Spin-Lattice Relaxation
    1995, Vol. 60, Issue 5, pp. 719–735 [Abstract]
  • Ladislav Novotný, Anna Vachálková and Alois Pískala
    Polarographic Reduction and Potential Carcinogenity of Synthetic 1,3,5-Triazine Bases and Nucleosides
    1994, Vol. 59, Issue 7, pp. 1691–1698 [Abstract]
  • Alois Pískala, Milena Masojídková, David Šaman and Pavel Fiedler
    Structure of 5-azacytosine nucleosides in acid solutions
    1993, Vol. 58, Special Issue, pp. S26–S28 [Abstract]
  • Luboš Arnold, Jiří Smrt, Jaroslav Zajíček, Günther Ott, Michael Schiesswohl and Mathias Sprinzl
    Dimethylaminomethylene protected purine H-phosphonates in the synthesis of biologically active RNA (24-mer)
    1991, Vol. 56, Issue 9, pp. 1948–1956 [Abstract]
  • Alexander Kasal, Jenny Pokorná and Jaroslav Zajíček
    3β,11α,17-Trihydroxy-5-pregnen-20-one 11-hemisuccinate as a haptene for RIA of "17α-hydroxypregnenolone"
    1991, Vol. 56, Issue 6, pp. 1340–1347 [Abstract]
  • Alexander Kasal, Jaroslav Podlaha and Jaroslav Zajíček
    A-homo-B,19-dinorandrostanes from 6β-methanesulfonyloxy-5-methyl-19-nor-5β-androst-9-ene derivatives
    1991, Vol. 56, Issue 5, pp. 1070–1086 [Abstract]
  • Alois Pískala, Petr Alexander and Jiří Burkhard
    Synthesis of some anomeric 4,6-disubstituted-1-(2-deoxy-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-ones
    1990, Vol. 55, Special Issue, pp. S53–S56 [Abstract]
  • Miroslav Ledvina, Jiří Farkaš, Jaroslav Zajíček, Jan Ježek and Milan Zaoral
    An alternative synthesis of O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-(1→4)-N-acetylnormuramoyl-L-α-aminobutanoyl-D-isoglutamine
    1989, Vol. 54, Issue 10, pp. 2784–2794 [Abstract]
  • Alexander Kasal and Jaroslav Zajíček
    Spontaneous transannular reaction in Δ9-unsaturated A-homo-B,19-dinorsteroids
    1989, Vol. 54, Issue 5, pp. 1327–1335 [Abstract]
  • Václav Černý, Jaroslav Zajíček and Miroslav Strnad
    2α,3α-Dihydroxy-7-oxa-6-oxo-B-homo-5α-pregnan-21-oic acid and its derivatives as brassinolide analogues
    1987, Vol. 52, Issue 1, pp. 215–222 [Abstract]
  • Ivan Bašnák, Jiří Farkaš, Jaroslav Zajíček and Zdeněk Havlas
    Synthesis of anomeric 5-cyclopropyl-2'-deoxyuridines and 1H NMR spectroscopic study of their conformation
    1986, Vol. 51, Issue 8, pp. 1764–1771 [Abstract]
  • Alexander Kasal and Jaroslav Zajíček
    Solvolysis of Westphalen-type compounds
    1986, Vol. 51, Issue 7, pp. 1462–1475 [Abstract]
  • Ladislav Kohout, Vijay Kumar Sethi, Jaroslav Zajíček and Alexander Kasal
    Solvolytic reactions of empiric 3-methanesulfonyloxy-7-benzoyloxy-5β,6β-cyclopropanocholestanes
    1986, Vol. 51, Issue 2, pp. 436–446 [Abstract]
  • Helena Velgová and Jaroslav Zajíček
    Reaction of 3,4a-disubstituted 4,4-dimethyl-5,6β-epoxy-A-homo-5β-cholestane derivatives with reducing agents
    1985, Vol. 50, Issue 11, pp. 2457–2470 [Abstract]
  • Milena Masojídková, Jaroslav Zajíček, Miloš Buděšínský, Ivan Rosenberg and Antonín Holý
    Conformational study on ribonucleoside O-phosphonylmethyl derivatives by 1H NMR spectroscopy
    1985, Vol. 50, Issue 8, pp. 1899–1905 [Abstract]
  • Jiří Joska, Jan Fajkoš and Jaroslav Zajíček
    Synthesis of 3β,4β-cyclopropano-19-nor-A-homosteroids
    1985, Vol. 50, Issue 7, pp. 1611–1617 [Abstract]
  • Jiří Závada, Václav Pechanec, Jaroslav Zajíček, Ivan Stibor and Antonín Vítek
    Effects of salt concentration and counterion on stability of alkali ion-18-crown-6 complexes in aqueous and methanolic solution: A conflicting evidence from potentiometric and sodium-23 NMR studies
    1985, Vol. 50, Issue 5, pp. 1184–1193 [Abstract]
  • Helena Velgová and Jaroslav Zajíček
    Oxidation and epoxidation of 4,4-dimethyl-A-homo-5-cholesten-4a-ols
    1985, Vol. 50, Issue 1, pp. 114–131 [Abstract]
  • Ladislav Kohout and Jaroslav Zajíček
    Lead tetraacetate oxidation of 3β-acetoxy-B-homo-5α-cholestan-7aβ-ol
    1984, Vol. 49, Issue 1, pp. 301–305 [Abstract]
  • Jaroslav Zajíček, Miloš Buděšínský and Jiří Farkaš
    Conformational study of blocked pentofuranoses and their 1,5-anhydro derivatives by 1H NMR spectroscopy
    1984, Vol. 49, Issue 1, pp. 235–243 [Abstract]
  • Alois Pískala, Abdul Hamid Rehan and Manfred Schlosser
    Wittig-Reaktion von Triphenylphosphonio-alkyliden mit substituierten Benzaldehyden: Hammett-Beziehung und teilweise Reversibilität der Addukt-bildung
    1983, Vol. 48, Issue 12, pp. 3539–3551 [Abstract]
  • Jiří Joska, Jan Fajkoš and Jaroslav Zajíček
    Bromination of 19-acetoxy-4β,5-cyclopropano-5β-cholestan-3-one
    1983, Vol. 48, Issue 12, pp. 3474–3481 [Abstract]
  • Jan Fajkoš, Jiří Joska and Jaroslav Zajíček
    The bromination of the epimeric 4,5-cyclopropanocholestan-3-ones
    1983, Vol. 48, Issue 12, pp. 3455–3473 [Abstract]
  • Alois Čihák, Milagros Carcia Mesa and Hideo Inoue
    Depression of DNA synthesis in the thymus of zinc-treated adult mice
    1983, Vol. 48, Issue 10, pp. 3020–3023 [Abstract]
  • Alois Čihák
    Character of metal ion precipitation of partially purified uridine kinase and phosphomonoesterase from various tissues of rats
    1978, Vol. 43, Issue 8, pp. 2089–2095 [Abstract]
  • Alois Čihák and Antonín Holý
    Distribution and metabolic transformation of 9-(S)-(2,3-dihydroxypropyl)adenine, an effective virostatic agent, in mice
    1978, Vol. 43, Issue 8, pp. 2082–2088 [Abstract]