Collect. Czech. Chem. Commun. 1984, 49, 235-243

Conformational study of blocked pentofuranoses and their 1,5-anhydro derivatives by 1H NMR spectroscopy

Jaroslav Zajíček, Miloš Buděšínský and Jiří Farkaš

Institute of Organic Chemistry and Biochemistry , Czechoslovak Academy of Sciences, 166 10 Prague 6


Preferred conformations of the furanose ring and conformer population about the C(5)-C(4) bond in a series of benzoylated pentofuranosyl cyanides have been determined from their 1H NMR spectra. For the 1,5-anhydropentofuranose derivatives the results of the 1H NMR spectral analysis have been compared with the quantum chemical calculations.