Collect. Czech. Chem. Commun. 1995, 60, 1191-1195

Synthesis of Alkyl 1,2-Dicyanopyrrolidino[1,2-f]phenanthridine-3-carboxylates

Milan Potáčeka, Tomáš Topinkaa, Jiří Dostálb and Otakar Humpaa

a Department of Organic Chemistry, Masaryk University, 611 37 Brno, Czech Republic
b Department of Biochemistry, Masaryk University, 662 43 Brno, Czech Republic


Alkyl 1,2-dicyanopyrrolidino[1,2-f]phenanthridine-3-carboxyla tes II were prepared from 5-(alkoxycarbonylmethyl)phenanthridinium bromides I and fumaronitrile in the presence of triethylamine. The products II underwent spontaneous dehydrogenation to give pyrrolino[1,2-f]phenanthridines III. The structures of the products were determined by spectral methods (IR, NMR, MS).