Collect. Czech. Chem. Commun.
1991, 56, 2402-2405
https://doi.org/10.1135/cccc19912402
Search for new analeptics: Homoanalogues of dimefline-type derivatives
Maria Carraraa, Francesca Capolongoa, Lorenzo Cimaa, Giuseppina Fabbrib, Angela Rampab, Piero Valentib and Paolo Da Reb
a Department of Pharmacology, University of Padua, Italy
b Department of Pharmaceutical Sciences, University of Bologna, Italy
Abstract
The preparation and the pharmacological profile of a selected number of homologues at C2 (homoflavones) of dimefline-type analeptics are described. The structural modifications introduced in I seems to cause a remarkable alteration of the CNS stimulating pattern so that the new compounds are to be considered as minor analeptics.
