Collect. Czech. Chem. Commun. 1988, 53, 198-201

A novel cytoskeletal associated protein: Genomic organization and protein pattern

Haralabos Zorbas, Ernst Pöschl, Antonia Pöschl and Peter K. Müller

Max-Planck-Institut für Biochemie, 8033 Martinsried, F.R.G.


c-DNA clones were constructed from chicken sternal m-RNA and screened for recognizing those m-RNA species the amount of which decreases during chondrocyte dedifferentiation. One such clone was used to screen a chicken genomic library and, furthermore, to deduce peptide sequences suitable for raising antibodies. Initial results on the genomic structure and on some biochemical and immunochemical properties are presented.