Collect. Czech. Chem. Commun. 1985, 50, 690-696

1H NMR spectra of some juvabione analogues

R. K. Mahajan, Neelam Gupta and Satinder K. Uppal

Department of Chemistry, Himachal Pradesh University, Summer Hill, Summer Hill, Shimla 171 005, India


A number of aromatic aza-analogues of juvabione and dehydrojuvabione have been synthetized by treatment of substituted benzylamine with 3-methylbutanoyl chloride and 3-methyl-2-butenoyl chloride. Reaction of substituted phenoxyacetyl chlorides with isopropylamine and 2-propanol gives other series of aromatic juvabione analogues. The 1H NMR spectra of some analogues are discussed.