Collect. Czech. Chem. Commun.
2010, 75, 675-683
https://doi.org/10.1135/cccc2009550
Published online 2010-06-17 08:32:35
Biotransformation of testosterone and progesterone by Penicillium digitatum MRC 500787
Kudret Yildirim*, Fatih Gulsan and Ilknur Kupcu
Chemistry Department, Sakarya University, 54187 Sakarya, Turkey
Abstract
The biotransformation of testosterone and progesterone by Penicillium digitatum MRC 500787 for 5 days is described. The biotransformation of testosterone afforded 5α-androstane-3,17-dione, 3α-hydroxy-5α-androstan-17-one, 3β-hydroxy-5α-androstan-17-one and androst-4-ene-3,17-dione. The biotransformation of progesterone afforded 5α-pregnane-3,20-dione.
Keywords: Xenobiotics; Steroids; Biotransformations; Penicillium digitatum; Microbial hydrogenation; Whole-cell biocatalysis.
References: 32 live references.
