Collect. Czech. Chem. Commun. 2003, 68, 1904-1913

Transition Metal Complex Catalysis in Fine Organic Synthesis. A Personal Account

Irina P. Beletskaya* and Andrei V. Cheprakov

Department of Chemistry, Moscow State University, 119899 Moscow, Russia


The development of catalytic systems for palladium catalyzed C-C and C-heteroatom bond formation is overviewed. Attention is focused on the issues relevant for environmental and technological safety of the processes: high catalytic efficiency, reactions in the absence of expensive non-recoverable phosphine ligands, the use of water and aqueous media, atom efficient transformations, etc.

Keywords: Homogeneous catalysis; Transition metal complexes; Cross-coupling reactions; Palladium; Ligand-free reactions; Phosphine ligands; Aqueous conditions; Microemulsions.

References: 32 live references.