Collect. Czech. Chem. Commun. 2001, 66, 1746-1752

Oxidation of Furost-20(22)-enes with 3-Chloroperoxybenzoic Acid and Osmium Tetroxide

Jacek W. Morzycki*, Izabella Jastrzębska and Krzysztof S. Katryński

Institute of Chemistry, University of Bialystok, al. Pilsudskiego 11/4, 15-443 Bialystok, Poland


6β-Methoxy-3α,5-cyclo-5α-furost-20(22)-ene and its 17α-hydroxy derivative were oxidized with 3-chloroperoxybenzoic acid and OsO4. The former compound afforded hydroxylated products, whereas the latter underwent degradation to C21 or C19 steroids.

Keywords: Pseudosapogenins; Furostanes; Oxidations; Steroids; Steroidal saponins.

References: 20 live references.