Collect. Czech. Chem. Commun. 1997, 62, 925-940

Axially Chiral Synthons for Dendrimer Synthesis

Vít Lellek and Ivan Stibor

Department of Organic Chemistry, Prague Institute of Chemical Technology, 166 28 Prague 6,Czech Republic


Axially chiral synthons for chiral dendrimer construction based on 2,2'-dihydroxy-1,1'-binaphthalene-3,3'-dicarboxylic acid were prepared, namely, chiral connecting units (3, 6, 8), chiral branching units (10, 12, 14), and chiral surface units (5, 17). Regioselective chloromethylation of methyl 3'-acetoxymethyl-2,2'-dimethoxy-1,1'-binaphthalene-3-carboxylate (7) was also studied.

Keywords: Dendrimers; Chiral synthons; Binaphthols.