Collect. Czech. Chem. Commun. 1997, 62, 516-520

Effect of 2-Alkylthio-4-pyridinecarbothiamides on Photosynthetic Electron Transport in Spinach Chloroplasts

Katarína Kráľováa, František Šeršeňa, Věra Klimešováb and Karel Waisserb

a Institute of Chemistry, Comenius University, 842 15 Bratislava, Slovak Republic
b Department of Inorganic and Organic Chemistry, Charles University, 501 65 Hradec Králové, Czech Republic


2-Alkylthio-4-pyridinecarbothiamides (1) inhibit photosynthetic electron transport in spinach chloroplasts. The dependence of photosynthesis-inhibiting activity upon the lipophilicity of 2-alkylthio substituent shows quasi-parabolic course with maximum effectiveness at 2-octyl derivative. The site of action of 1 is the intermediate D+, corresponding to tyrosine radical, which is situated in D2 protein on the donor side of photosystem 2.

Keywords: 2-Alkylthio-4-pyridinecarbothiamides; Photosynthesis inhibition; Photosynthetic centres.