Collect. Czech. Chem. Commun. 1997, 62, 494-497

C-Formylation of Some 2(3H)-Benzazolones and 2H-1,4-Benzoxazin-3(4H)-one

Ognyan I. Petrov, Veneta B. Kalcheva and Antonina Ts. Antonova

Department of Chemistry, Sofia University, James Bourchier Ave. 1, 1126 Sofia, Bulgaria


The C-formylation of 1,3-dimethyl-2(3H)-benzimidazolone and 4-methyl-2H-1,4-benzoxazin-3(4H)-one was performed using 1,1-dichloromethyl methyl ether at the Friedel-Crafts reaction conditions. The formylation of 3-methyl-2(3H)-benzoxa- and -thiazolone at the 6-position was carried out by modified Duff's method with hexamethylenetetramine in trifluoroacetic acid.

Keywords: Formylation; Benzoheterocycles.