Collect. Czech. Chem. Commun. 1997, 62, 1747-1753

Gradient-Enhanced Inverse-Detected NMR Techniquesfor Determination of 1H-15N Coupling Constants in 2,2-Dimethylpenta-3,4-dienal Derivatives

Radek Marek

NMR Laboratory, Masaryk University, Kotlářská 2, 611 37 Brno, Czech Republic


Determination of 15N chemical shifts and heteronuclear coupling constants of substituted 2,2-dimethylpenta-3,4-dienal hydrazones is presented. The chemical shifts were determined by gradient-enhanced inverse-detected NMR techniques and 1H-15N coupling constants were extracted from phase-sensitive gradient-enhanced single-quantum multiple bond correlation experiments. Stereospecific behaviour of the coupling constants 2J(1H,15N) and 1J(1H,13C) has been used to determine the configuration on a C=N double bond. The above-mentioned compounds exist predominantly as E isomers in deuteriochloroform.

Keywords: 2,2-Dimethylpenta-3,4-dienal; Hydrazones; Inverse-detected NMR spectroscopy; 15N chemical shifts; 1H-15N coupling constants.