Collect. Czech. Chem. Commun. 1997, 62, 62-68

Comparison of (R)-(-)-6,6'-Bis(3,5-dinitrobenzamido)biphenyl-2,2'-dicarboxylic and (S)-(+)-6,6'-Bis-(3,5-dinitrobenzamidomethyl)biphenyl-2,2'-dicarboxylic Acids as Chiral HPLC Selectors

Miloš Tichý, Luděk Ridvan and Jiří Závada

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 166 10 Prague 6, Czech Republic


The title optically active diacids (R)-I and (S)-II of known absolute configuration were investigated as selectors in HPLC separation of enantiomers. With a standard set of benzamido alcohols and biaryl compounds, the separation was less efficient and less general than that found for selectors based on studied previously.

Keywords: Chiral stationary phase; C2 Symmetry; Biaryl.