Collect. Czech. Chem. Commun. 1994, 59, 1100-1104

13C NMR Chemical Shift Assignments of Alkyl Chains of Histamine Analogous ω-Aminoalkylheterocycles and Bicyclic Derivatives

Martin Pohl, Wolf-Dieter Bloedorn, Clemens Mügge and Jürgen Liebscher

Fachbereich Chemie, Humboldt-Universität Berlin, Hessische Str. 1-2, D-10115 Berlin, Germany


ω-Aminoalkylheterocycles and aromatics as well as bicyclic azolodiazepine derivatives were investigated by means of CH-COSY and INADEQUATE experiments. The 13C NMR shifts of all carbon atoms of the aminopropyl and aminobutyl moieties could be assigned. The benzylic position of the ω-aminopropyl moieties appears most upfield rather than more downfield like erroneously reported in the literature.