Collect. Czech. Chem. Commun.
1994, 59, 461-466
https://doi.org/10.1135/cccc19940461
The Gas-Solid-Phase 2,5-Dioxopiperazine Synthesis. Cyclization of Vaporous Dipeptides on Silica Surface
Vladimir A. Basiuk and Taras Yu. Gromovoy
Institute of Surface Chemistry, Academy of Sciences of the Ukraine, Prospekt Nauki 31, Kiev 252650, Ukraine
Abstract
The "gas solid-phase" method is used for the preparation of both symmetric and asymmetric 2,5-dioxopiperazines via cyclization of vaporous linear dipeptides in the presence of silica.
