Collect. Czech. Chem. Commun.
1994, 59, 2293-2302
https://doi.org/10.1135/cccc19942293
Quantitative Relationships Between Inhibition of Photosynthesis and Lipophilicity of Piperidinoethyl Alkoxyphenylcarbamates
Katarína Kráľováa, Dušan Loosa and Jozef Čižmárikb
a Institute of Chemistry, Comenius University, 842 15 Bratislava, Slovak Republic
b Department of Pharmaceutical Chemistry, Comenius University, 832 32 Bratislava, Slovak Republic
Abstract
Piperidinoethyl esters of 2-, 3- and 4-alkoxy substituted phenylcarbamic acids (PAPC) inhibit photosynthetic processes in alga Chlorella vulgaris and spinach chloroplasts. These inhibitory activities of PAPC were correlated with chromatographically determined lipophilicity characteristics log k' (from HPLC) and Kovats indices KIO (from gas chromatography) using parabolic and bilinear model. Both theoretical models are suitable for description of studied correlations, however from the viewpoint of statistical analysis Kubinyi's bilinear model gives better results.
