Collect. Czech. Chem. Commun. 1992, 57, 1770-1774

Studies with Polyfunctionally Substituted Heterocycles: Novel Syntheses of Pyrido[4,3-d]pyridazines and of Pyrido[3,4-d]pyridazines

Fatma M. Manhia, Salem E. Zayedb, Fatma A. Alia and Mohamed Hilmy Elnagdic

a National Organization for Drug Control and Research, Giza, A. R. Egypt
b Department of Chemistry, Faculty of Science, University of Assute, Quena, A. R. Egypt
c Department of Chemistry, Faculty of Science, Cairo University, Giza, A. R. Egypt


As a part of our programme aimed at developing efficient syntheses of polyfunctionally substituted azines and condensed azines, we have in the past reported efficient syntheses of compounds I-III. In conjunction of this work we report results of our further studies aimed at exploring the synthetic potentialities of I-III.