Collect. Czech. Chem. Commun. 1990, 55, 535-539

Reaction of mercaptoacetic acid and chloroacetyl chloride with benzalamino thiazolyl coumarins

Udarapu Veerabhadraiah, Vedeela Rajeswar Rao and Tadepalcy Venkata Padmanabha Rao

Department of Chemistry, Kakatiya University, Warangal - 506 009, India


2-Aryl-3-[4-(2-oxo-2H-1-benzopyran-3-yl)-2-thiazolyl]-4-thiazolidinones (III), have been synthesized by the reaction of Schiff's bases (II) derived from 3-(2-amino-4-thiazolyl)-2H-1-benzopyran-2-ones (I) with mercaptoacetic acid. The Schiff's bases on reaction with chloroacetyl chloride in the presence of triethylamine in dioxane gave chloroacetamido derivative (IV) instead of expected compound V.