Collect. Czech. Chem. Commun. 1990, 55, 524-534

Nitriles in heterocyclic synthesis: A novel route for the synthesis of naphthodipyrans, pyridines. 2H- and 4H-Pyrans

Abdel Ghani A. Elagameya, Fathy M. A. El-Taweela, Salah Z. A. Sowellima, Mamdouh A. Sofana and Mohamed H. Elnagdib

a Chemistry Department, Mansoura University, Damietta, Egypt
b Chemistry Department, Cairo University, Cairo, Egypt


Naphtho[2,1-b:5,6-b']dipyrans and naphtho[1,2-b:6,5-b']dipyrans were synthesized by the reaction of cinnamonitriles with 2,3-, 1,5-, 1,6-naphthalenediols, respectively. Polysubstituted pyridines, 2H-pyrans and 4H-pyrans were also synthesized from cinnamonitriles, 2-hydroxyacetophenone and 3-acetyl-4-hydroxy-1-methylcarbostyril, respectively.