Collect. Czech. Chem. Commun.
1989, 54, 533-535
https://doi.org/10.1135/cccc19890533
Mimicking bioactive peptides. [8-Nβ-Guanidoacetyl-α,β-diaminopropionic acid]vasopressin
Milan Zaorala and Viktor Krchňákb
a Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6
b Léčiva–Pharmaceuticals, 143 10 Prague 4
Abstract
The title compound was prepared by solid phase methodology. It has 34.2 I.U./mg of pressor activity, 5.8 I.U./mg of uterotonic activity and by 3-4 orders of magnitude lower antidiuretic activity than DDAVP.
