Collect. Czech. Chem. Commun. 1988, 53, 209-211

A new adhesive protein mediating the interaction between mesenchymal cells and elastin fibers: Elastonectin

Ladislas Robert and William Hornebeck

Laboratoire de Biochimie du Tissu Conjonctif, UA CNRS 1174 Faculté de Médecine, Université Paris XII, 94010 CRETEIL CEDEX, France


An inducible adhesive protein was demonstrated in smooth muscle cells and fibroblasts which mediate the adhesion of mesenchymal cells to elastic fibers. It is proposed to designate it elastonectin. This protein plays probably an important role in the morphogenesis of elastic tissue and its degradation is probably involved in the formation of the atherosclerotic plaque.