Collect. Czech. Chem. Commun.
1987, 52, 443-452
https://doi.org/10.1135/cccc19870443
Kinetic analysis of competitive reactions of isothiocyanates with hydroxyl and alkoxide ions
Jozef Augustín and Štefan Baláž
Department of Biochemical Technology, Slovak Institute of Technology, 812 37 Bratislava
Abstract
The reaction of isothiocyanates with hydroxyl and alkoxide ions has been followed spectrophotometrically in alkaline aqueous-alcoholic solutions. Both the nucleophiles are added to the carbon atom of isothiocyanate group in a competition reaction. The effects of concentration of the nucleophiles, temperature, and acid-base properties of the alcoholic group have been followed on the reaction course. The possibility of analogous reactions in real biological systems is discussed.
