Collect. Czech. Chem. Commun.
1987, 52, 437-442
https://doi.org/10.1135/cccc19870437
Reversibility of reactions of phenylhydrazonopropanedinitriles with thiols
Ernest Šturdík, Marián Antalík and Ľudovít Drobnica
Department of Technical Microbiology and Biochemistry, Slovak Institute of Technology, 812 37 Bratislava
Abstract
S-Benzyl (2-phenylhydrazono)cyanothioacetimidate, as a model product of the reactions of phenylhydrazonopropanedinitriles with thiols, is decomposed in physiological medium into the original reactants, i.e. benzyl mercaptan and phenylhydrazonopropanedinitrile. The decomposition rate increases with increasing pH value of the medium. The found reversibility of the reactions of phenylhydrazonopropanedinitriles with thiols is discussed with respect to elucidation of bioactivity of phenylhydrazonopropanedinitriles.
