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Collect. Czech. Chem. Commun. 1985, 50, 103-113
https://doi.org/10.1135/cccc19850103

Synthesis of new branched polypeptides with poly(lysine)back bone

Ferenc Hudecz and Mária Szekerke

Research Group for Peptide Chemistry, Hungarian Academy of Sciences, Budapest, Hungary

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  • Khorolsuren Zambaga, Lang Orsolya, Pallinger Eva, Foldes Anna, Szabolcs Gyulai‐Gaál, Varga Gabor, Mezo Gabor, Vag Janos, Kohidai Laszlo: Functional and cell surface characteristics of periodontal ligament cells (PDLCs) on RGD‐synthetic polypeptide conjugate coatings. J of Periodontal Research 2020, 55, 713. <https://doi.org/10.1111/jre.12760>
  • Manea Marilena, Mezö Gábor, Hudecz Ferenc, Przybylski Michael: Polypeptide conjugates comprising a β‐amyloid plaque‐specific epitope as new vaccine structures against Alzheimer's disease. Biopolymers 2004, 76, 503. <https://doi.org/10.1002/bip.20160>
  • Nagy Ildikó B., Dancs Andrea, Kóczán György, Mezö Gábor, Hudecz Ferenc: Conjugation of HS-Oligopeptides with Polymeric Branched Chain Polypeptides Containing Multiple Amino Groups. Journal of Bioactive and Compatible Polymers 2000, 15, 139. <https://doi.org/10.1177/088391150001500203>
  • Wilkinson Katalin A., Hudecz Ferenc, Vordermeier H. Martin, Ivanyi Juraj, Wilkinson Robert J.: Enhancement of the T cell response to a mycobacterial peptide by conjugation to synthetic branched polypeptide. Eur J Immunol 1999, 29, 2788. <https://doi.org/10.1002/(SICI)1521-4141(199909)29:09<2788::AID-IMMU2788>3.0.CO;2-4>
  • Wilkinson Katalin A., Hudecz Ferenc, Vordermeier H. Martin, Ivanyi Juraj, Wilkinson Robert J.: Enhancement of the T cell response to a mycobacterial peptide by conjugation to synthetic branched polypeptide. Eur. J. Immunol. 1999, 29, 2788. <https://doi.org/10.1002/(SICI)1521-4141(199909)29:09<2788::AID-IMMU2788>3.0.CO;2-4>
  • Pató Janos, Ulbrich Karel, Subr Vladimir, Baker Peter, Mezö Gábor, Hudecz Ferenc: Synthesis of Macromolecular Conjugates of a Urokinase Inhibitor: Amiloride. Journal of Bioactive and Compatible Polymers 1999, 14, 99. <https://doi.org/10.1177/088391159901400201>
  • Idei Miklós, Dibó Gábor, Bogdán Katalin, Mezö Gábor, Horváth Anikó, Érchegyi Judit, Mészáros György, Teplán István, Kéri György, Hudecz Ferenc: Analysis of macromolecular branched chain polypeptides by capillary electrophoresis and micellar electrokinetic chromatography. Electrophoresis 1996, 17, 1357. <https://doi.org/10.1002/elps.1150170813>
  • Pimm Malcolm V, Gribben Sandra J, Bogdán Katalin, Hudecz Ferenc: The effect of charge on the biodistribution in mice of branched polypeptides with a poly(l-lysine) backbone labelled with 125I, 111In or 51Cr. J Controlled Release 1995, 37, 161. <https://doi.org/10.1016/0168-3659(95)00080-R>
  • Hudecz F., Clegg J. A., Kajtar J., Embleton M. J., Pimm M. V., Szekerke M., Baldwin R. W.: Influence of carrier on biodistribution and in vitro cytotoxicity of methotrexate-branched polypeptide conjugates. Bioconjugate Chem. 1993, 4, 25. <https://doi.org/10.1021/bc00019a004>
  • Hudecz F., Gaál D., Kurucz I., Lányi Á., Kovács A.L., Mezö G., Rajnavölgyi É., Szekerke M.: Carrier design: cytotoxicity and immunogenicity of synthetic branched polypeptides with poly(L-lysine) backbone. J Controlled Release 1992, 19, 231. <https://doi.org/10.1016/0168-3659(92)90079-7>
  • Hudecz Ferenc, Clegg J. A., Kajtar J., Embleton M. J., Szekerke M., Baldwin R. W.: Synthesis, conformation, biodistribution and in vitro cytotoxicity of daunomycin-branched polypeptide conjugates. Bioconjugate Chem. 1992, 3, 49. <https://doi.org/10.1021/bc00013a008>
  • Clegg J. A., Hudecz F., Mezo G., Pimm M. V., Szekerke M., Baldwin R. W.: Carrier design: biodistribution of branched polypeptides with a poly(L-lysine) backbone. Bioconjugate Chem. 1990, 1, 425. <https://doi.org/10.1021/bc00006a009>
  • Mező G., Hudecz F., Kajtár J., Szókán Gy., Szekerke M.: The influence of the side‐chain sequence on the structure–activity correlations of immunomodulatory branched polypeptides. Synthesis and conformational analysis of new model polypeptides. Biopolymers 1989, 28, 1801. <https://doi.org/10.1002/bip.360281013>
  • Rajnavölgyi É., Lányi Á, Hudecz F., Kurucz I., Kiss K., László G., Szekerke M., Gergely J.: Structural characteristics influencing the carrier function of synthetic branched polypeptides based on poly[Lys-(dl-Ala)3)]backbone. Molec Immunol 1989, 26, 949. <https://doi.org/10.1016/0161-5890(89)90113-2>
  • Hudecz Ferenc, Kajtȧr Judit, Kurucz IstvȧN, Kovȧcs Attila L., Szekerke MȧRia: Investigation of the carrier function of polypeptides. Synthesis, conformation and cytotoxicity of oxazolone conjugates of poly(Lys) and poly[Lys‐(DL‐ALAm)]. Makromolekulare Chemie. Macromolecular Symposia 1988, 19, 107. <https://doi.org/10.1002/masy.19880190108>
  • Hudecz Ferenc, Kajtár Judit, Szekerke Mária: Influence of side-chain-terminating moieties on the conformation of branched polypeptides and their conjugates with 4-ethoxymethylene-2-phenyl-5(4H)-oxazolone. biophys chem 1988, 31, 53. <https://doi.org/10.1016/0301-4622(88)80008-5>
  • Hudecz Ferenc, Mezö Gábor, Szekerke Mária, Gergely János, Rajnavölgyi Éva: Isotype distribution and fine specificity of the antibody response of inbred mouse strains to four compounds belonging to a new group of synthetic branched polypeptides. Molec Immunol 1986, 23, 27. <https://doi.org/10.1016/0161-5890(86)90168-9>
  • HUDECZ F., SZEKERKE M.: ChemInform Abstract: SYNTHESIS OF NEW BRANCHED POLYPEPTIDES WITH A POLY(LYSINE) BACKBONE. Chemischer Informationsdienst 1985, 16. <https://doi.org/10.1002/chin.198522354>