Collect. Czech. Chem. Commun.
1984, 49, 2141-2147
https://doi.org/10.1135/cccc19842141
Reactions of 1-cyano-1-R-2-(5-X-2-furyl)ethylenes with nucleophilic reagents
Rudolf Kada, Viera Knoppová, Jaroslav Kováč and Naděžda Mäčková
Department of Organic Chemistry, Slovak Institute of Technology, 812 37 Bratislava
Abstract
The Knoevenagel condensation of phenylsulphonylacetonitrile and benzoylacetonitrile with 5-X-furane-2-carbaldehydes ( X = Br, NO2, C6H5S, C6H5SO2) has been used for preparation of the respective condensation products 1-cyano-1-fenylsulphonyl-2-(5-X-2-furyl)- and 1-cyano-1-benzoyl-2-(5-X-2-furyl)ethylenes. These condensation products react with nucleophilic reagents which replace the group X at the 5 position of the furane nucleus. These nucleophilic substitutions have been also studied kinetically.
