Collect. Czech. Chem. Commun.
1984, 49, 2557-2561
https://doi.org/10.1135/cccc19842557
Papain-catalyzed synthesis of phenylhydrazides of N-acylamino acids
Václav Čeřovský and Karel Jošt
Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6
Abstract
Phenylhydrazides of Nα-acyl derivatives of all coded amino acids, except proline, were prepared by papain (E.C. 3.4.22.2)-catalyzed synthesis. Comparison of yields affords information about the suitability of the amino acid in position P1 in papain-catalyzed syntheses of peptides.