Collect. Czech. Chem. Commun. 1981, 46, 1492-1494
https://doi.org/10.1135/cccc19811492

Reactions of benzoyl isothiocyanates with 5-substituted tetrazoles

Michal Uher, Jozef Foltín, František Považanec and Jaroslav Kováč

Department of Organic Chemistry, Slovak Institute of Technology, 880 37 Bratislava

Abstract

A method of preparing 2,5-disubstituted 1,3,4-oxadiazoles from benzoyl isothiocyanates and 5-substituted tetrazoles is described. The transformation of the tetrazole into a 1,3,4-oxadiazole ring takes place readily under neutral conditions giving high yields of the desired products.