Collect. Czech. Chem. Commun. 1981, 46, 792-797

Stimulatory effect of the 2-palmitamidoethyl ester of adenosine 5'-phosphate on the activity of rabbit skeletal muscle protein kinase

Sixtus Hyniea and Jiří Smrtb

a Institute of Pharmacology, Faculty of General Medicine, Charles University, 128 00 Prague 2
b Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6


2-Palmitamidoethyl ester of adenosine 5'-phosphate (PEA-AMP) stimulates the rabbit skeletal muscle protein kinase in relatively narrow range of high drug concentration. Mechanism of this effect seems to be analogous to that of cyclic AMP.