Collect. Czech. Chem. Commun.
1980, 45, 1860-1865
https://doi.org/10.1135/cccc19801860
The reaction of 1,3-dichloro-1,1,3,3-tetraisopropyldisiloxane with cytosine arabinoside and 1-(6-deoxy-α-L-talofuranosyl)uracil
Wojciech T. Markiewicza, Nelly Sh. Padyukovab, Zdeněk Samekc and Jiří Smrtc
a Department of Stereochemistry of Natural Products, Institute of Organic Chemistry, Polish Academy of Sciences, 61-704 Poznan, Poland
b Institute of Molecular Biology, Academy of Sciences of the USSR, Moscow, USSR
c Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6, Czechoslovakia
Abstract
1,3-dichloro-1,1,3,3-tetraisopropyldisiloxane (I) reacts with cytosine arabinoside (II) in pyridine under the formation of 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)cytosine arabinoside (IIIa) and with 1-(6'-deoxy-α-L-talofuranosyl)uracil (V) under the formation of 2',3'-O-(tetraisopropyldisiloxane-1,3-diyl) 1-(6-deoxy-α-L-talofuranosyl)uracil (VIa).
