Collect. Czech. Chem. Commun. 1980, 45, 1850-1859

Simmons-Smith methylenation of the 4,5-double bond in 19-hydroxylated steroids

Jiří Joska and Jan Fajkoš

Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6


Simmons-Smith methylenation of 4-cholestene-3α,19-diol 19-monoacetate and of 4-cholestene-3β,19-diol 19-monoacetate has been studied and structure of the products established by spectral means.