Collect. Czech. Chem. Commun. 1980, 45, 274-293

The synthesis and mass spectra of some oxygen-bridged 5α-cholestane and B-homo-5α-cholestane derivatives

František Turečeka and Pavel Kočovskýb

a The Jaroslav Heyrovský Institute of Physical Chemistry and Electrochemistry, Czechoslovak Academy of Sciences, 121 38 Prague 2
b Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6


The synthesis and mass spectrometric behaviour of a series of oxygen-bridged α-cholestans and B-homo-5α-cholestans I-X are described. The differences in fragmentation patterns of these compounds are discussed in dependence on the position of the oxygen bridge, position and configuration of additional substituents and conformation of the A and B rings of the steroid skeleton.