Collect. Czech. Chem. Commun. 1980, 45, 135-141

Reactions and spectral properties of ethyl 5-aminofuroate and its derivatives

Josef Prousek, Adolf Jurášek and Jaroslav Kováč

Department of Organic Chemistry, Slovak Institute of Technology, 880 37 Bratislava


Ethyl 5-aminofuroate (II), prepared by reduction of ethyl 5-nitrofuroate (I), served for preparation of bifunctional α,β-substituted aminofurans IV-IX, acyl derivatives IIIa, IIIb and condensation product X. The latter reacted with diazomethane directly to afford the corresponding aziridine derivative XI. The synthesized compounds were characterized by spectral data (IR, UV, 1H-NMR, 13C-NMR (XI) and mass spectra.)