Crossref Cited-by Linking logo

Collect. Czech. Chem. Commun. 2011, 76, 957-988
https://doi.org/10.1135/cccc2011082
Published online 2011-07-07 13:16:17

Sugar-modified derivatives of cytostatic 6-(het)aryl-7-deazapurine nucleosides: 2′-C-methylribonucleosides, arabinonucleosides and 2′-deoxy-2′-fluoroarabinonucleosides

Petr Nauš, Pavla Perlíková, Radek Pohl and Michal Hocek*

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i., Gilead Sciences & IOCB Research Center, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic

Crossref Cited-by Linking

  • Malnuit Vincent, Smoleń Sabina, Tichý Michal, Poštová Slavětínská Lenka, Hocek Michal: Synthesis of Cyclic and Acyclic Nucleoside Phosphonates and Sulfonamides Derived from 6-(Thiophen-2-yl)-7-fluoro-7-deazapurine. Eur. J. Org. Chem. 2019, 2019, 5409. <https://doi.org/10.1002/ejoc.201900509>
  • Perlíková Pavla, Hocek Michal: Pyrrolo[2,3-d ]pyrimidine (7-deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides. Med. Res. Rev. 2017, 37, 1429. <https://doi.org/10.1002/med.21465>
  • Maier Lukáš, Khirsariya Prashant, Hylse Ondřej, Adla Santosh Kumar, Černová Lenka, Poljak Michal, Krajčovičová Soňa, Weis Erik, Drápela Stanislav, Souček Karel, Paruch Kamil: Diastereoselective Flexible Synthesis of Carbocyclic C-Nucleosides. J. Org. Chem. 2017, 82, 3382. <https://doi.org/10.1021/acs.joc.6b02594>
  • Konč Juraj, Tichý Michal, Pohl Radek, Hodek Jan, Džubák Petr, Hajdúch Marián, Hocek Michal: Sugar modified pyrimido[4,5-b]indole nucleosides: synthesis and antiviral activity. Med. Chem. Commun. 2017, 8, 1856. <https://doi.org/10.1039/C7MD00319F>
  • Nauš Petr, Caletková Olga, Perlíková Pavla, Poštová Slavětínská Lenka, Tloušťová Eva, Hodek Jan, Weber Jan, Džubák Petr, Hajdúch Marián, Hocek Michal: Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides. Bioorganic & Medicinal Chemistry 2015, 23, 7422. <https://doi.org/10.1016/j.bmc.2015.10.040>
  • Ren Hang, An Haoyun, Hatala Paul J, Stevens William C, Tao Jingchao, He Baicheng: Versatile synthesis and biological evaluation of novel 3’-fluorinated purine nucleosides. Beilstein J. Org. Chem. 2015, 11, 2509. <https://doi.org/10.3762/bjoc.11.272>
  • Perlíková Pavla, Eberlin Ludovic, Ménová Petra, Raindlová Veronika, Slavětínská Lenka, Tloušťová Eva, Bahador Gina, Lee Yu-Jen, Hocek Michal: Synthesis and Cytostatic and Antiviral Activities of 2′-Deoxy-2′,2′-difluororibo- and 2′-Deoxy-2′-fluororibonucleosides Derived from 7-(Het)aryl-7-deazaadenines. ChemMedChem 2013, 8, 832. <https://doi.org/10.1002/cmdc.201300047>
  • Tichý Michal, Pohl Radek, Tloušt’ová Eva, Weber Jan, Bahador Gina, Lee Yu-Jen, Hocek Michal: Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido[4,5-b]indole ribonucleosides. Bioorganic & Medicinal Chemistry 2013, 21, 5362. <https://doi.org/10.1016/j.bmc.2013.06.011>
  • Nauš Petr, Perlíková Pavla, Bourderioux Aurelie, Pohl Radek, Slavětínská Lenka, Votruba Ivan, Bahador Gina, Birkuš Gabriel, Cihlář Tomáš, Hocek Michal: Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2′-C-methylribonucleosides, 2′-deoxy-2′-fluoroarabinonucleosides, arabinonucleosides and 2′-deoxyribonucleosides. Bioorganic & Medicinal Chemistry 2012, 20, 5202. <https://doi.org/10.1016/j.bmc.2012.07.003>
  • Tichý Michal, Pohl Radek, Xu Hao Ying, Chen Yen-Liang, Yokokawa Fumiaki, Shi Pei-Yong, Hocek Michal: Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides. Bioorganic & Medicinal Chemistry 2012, 20, 6123. <https://doi.org/10.1016/j.bmc.2012.08.021>
  • Wójtowicz-Rajchel Hanna: Synthesis and applications of fluorinated nucleoside analogues. Journal of Fluorine Chemistry 2012, 143, 11. <https://doi.org/10.1016/j.jfluchem.2012.06.026>
  • Perlíková Pavla, Jornet Martínez Neus, Slavětínská Lenka, Hocek Michal: Synthesis of 2′-deoxy-2′-fluororibo- and 2′-deoxy-2′,2′-difluororibonucleosides derived from 6-(het)aryl-7-deazapurines. Tetrahedron 2012, 68, 8300. <https://doi.org/10.1016/j.tet.2012.07.033>
  • Naus Petr, Perlikova Pavla, Pohl Radek, Hocek Michal: ChemInform Abstract: Sugar-Modified Derivatives of Cytostatic 6-(Het)aryl-7-deazapurine Nucleosides: 2′-C-Methylribonucleosides, Arabinonucleosides and 2′-Deoxy-2′-fluoroarabinonucleosides. ChemInform 2011, 42, no. <https://doi.org/10.1002/chin.201147199>