Collect. Czech. Chem. Commun. 2011, 76, 1967-1978
Published online 2012-01-30 12:08:20

Copper- and amine-free Sonogashira–Hagihara coupling reaction catalyzed by Pd(0) nanoparticles supported on modified crosslinked polyacrylamide

Bahman Tamami* and Soheila Ghasemi

Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran


Pd(0) nanoparticles supported on modified crosslinked polyacrylamide containing phosphinite ligand was prepared. The complex was a highly efficient catalyst for the Sonogashira– Hagihara coupling reaction in the absence of a copper cocatalyst and an amine base under aerobic condition. This protocol can be applied for different aryl halides including chloroarenes. The catalyst can be reused several times without any considerable decrease in its activity because of low leaching of palladium metal from the support. Transmission electron microscopy (TEM) analysis of the catalyst revealed the formation of stable and polydispersed Pd(0) nanoparticles.

Keywords: C–C coupling; Heterogeneous catalysis; Palladium nanoparticle; Polyacrylamide support; Sonogashira coupling; Leaching.

References: 48 live references.