Collect. Czech. Chem. Commun. 2010, 75, 463-470
Published online 2010-04-15 12:38:39

Methanolysis of 3β-substituted 4,5-epoxyandrostanes catalysed by tetracyanoethylene

Cavit Uyanika,*, Aslihan Malayb, Hayal B. Sonmezb, Loic Queudruec and James R. Hansonc

a Department of Chemistry, University of Kocaeli, Izmit 41380, Kocaeli, Turkey
b Department of Chemistry, Gebze Institute of Technology, Gebze 41400, Kocaeli, Turkey
c Department of Chemistry, University of Sussex, Brighton, Sussex, BN1 9QJ, UK


The presence of a 3β-acetoxyl and 3β-hydroxyl group has been shown to modify the structures of the products arising from the tetracyanoethylene catalysed methanolysis of the epimeric 4,5-epoxyandrostanes when compared to the unsubstituted epoxyandrostanes.

Keywords: Steroids; Androstanes; Methanolysis; Epoxides; X-Ray crystallography.

References: 7 live references.