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Collect. Czech. Chem. Commun. 2010, 75, 201-220
https://doi.org/10.1135/cccc2009525
Published online 2010-02-24 10:38:09

Cytochrome P450 3A activities and their modulation by α-naphthoflavone in vitro are dictated by the efficiencies of model experimental systems

Lucie Bořek-Dohalská and Marie Stiborová*

Department of Biochemistry, Faculty of Natural Science, Charles University, Albertov 2030, 128 43 Prague 2, Czech Republic

Crossref Cited-by Linking

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  • Stiborová Marie, Indra Radek, Frei Eva, Kopečková Kateřina, Schmeiser Heinz H., Eckschlager Tomáš, Adam Vojtěch, Heger Zbyněk, Arlt Volker M., Martínek Václav: Cytochrome b 5 plays a dual role in the reaction cycle of cytochrome P450 3A4 during oxidation of the anticancer drug ellipticine. Monatsh Chem 2017, 148, 1983. <https://doi.org/10.1007/s00706-017-1986-9>
  • Popłoński Jarosław, Sordon Sandra, Tronina Tomasz, Bartmańska Agnieszka, Huszcza Ewa: Fungal metabolism of naphthoflavones. Journal of Molecular Catalysis B: Enzymatic 2015, 117, 1. <https://doi.org/10.1016/j.molcatb.2015.04.007>
  • Davydov Dmitri R., Davydova Nadezhda Y., Sineva Elena V., Kufareva Irina, Halpert James R.: Pivotal role of P450–P450 interactions in CYP3A4 allostery: the case of α-naphthoflavone. Biochemical Journal 2013, 453, 219. <https://doi.org/10.1042/BJ20130398>
  • Frank Daniel J., Denisov Ilia G., Sligar Stephen G.: Analysis of Heterotropic Cooperativity in Cytochrome P450 3A4 Using α-Naphthoflavone and Testosterone. Journal of Biological Chemistry 2011, 286, 5540. <https://doi.org/10.1074/jbc.M110.182055>
  • Levová Kateřina, Moserová Michaela, Kotrbová Věra, Šulc Miroslav, Henderson Colin J., Wolf C. Roland, Phillips David H., Frei Eva, Schmeiser Heinz H., Mareš Jaroslav, Arlt Volker M., Stiborová Marie: Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model. Toxicological Sciences 2011, 121, 43. <https://doi.org/10.1093/toxsci/kfr050>