Collect. Czech. Chem. Commun.
2010, 75, 59-79
https://doi.org/10.1135/cccc2010003
Published online 2010-02-08 13:44:14
Random mutagenesis of human serine racemase reveals residues important for the enzymatic activity
Hillary E. Hoffmana,b, Jana Jiráskováa,b, Marketa Zvelebilc and Jan Konvalinkaa,b,*
a Department of Biochemistry, Faculty of Science, Charles University in Prague, Hlavova 8, 128 43 Prague 2, Czech Republic
b Gilead Sciences and IOCB Research Center, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i., Flemingovo nám. 2, 166 10 Prague 6, Czech Republic
c Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, United Kingdom
Crossref Cited-by Linking
- Wang C.-Y., Ku S. C., Lee C.-C., Wang A. H.- J.: Modulating the function of human serine racemase and human serine dehydratase by protein engineering. Protein Engineering Design and Selection 2012, 25, 741. <https://doi.org/10.1093/protein/gzs078>
- Conti Paola, Tamborini Lucia, Pinto Andrea, Blondel Arnaud, Minoprio Paola, Mozzarelli Andrea, De Micheli Carlo: Drug Discovery Targeting Amino Acid Racemases. Chem. Rev. 2011, 111, 6919. <https://doi.org/10.1021/cr2000702>
