Collect. Czech. Chem. Commun. 2009, 74, 515-534
https://doi.org/10.1135/cccc2008183
Published online 2009-03-18 11:47:05

Synthesis of 3′-O-(2-cyanoethyl)-2′-deoxythymidine-5′-phosphate as a model compound for evaluation of cyanoethyl cleavage

Angelika C. Kellera,*, Saulius Servab, Diana C. Knappa, Marek Kwiatkowskic and Joachim W. Engelsa

a Institut für Organische Chemie und Chemische Biologie, J. W. Goethe Universität Frankfurt am Main, Max-von-Laue Str. 7, 60438 Frankfurt am Main, Germany
b Fermentas UAB, V. Graiciuno 8, 02241 Vilnius, Lithuania
c Oligovation AB, Dag Hammarskjölds väg 32B, Uppsala Science Park, 751 83 Uppsala, Sweden

Individual author index pages


Other CCCC articles of these authors

  • Thomas J. Lehmann, Karin Schwarzer, Markus Schweitzer and Joachim W. Engels
    Thermodynamic and CD-spectroscopic characterization of self-complementary methyl- and benzyl-modified d(CGCpGCG)-hexamers
    Symposium Series 1999, Vol. 2, pp. 302–305 [Abstract]
    Published online 2016-05-08 23:33:22
  • Thorsten Strube and Joachim W. Engels
    Synthesis and thermodynamic properties of different 2'-fluoro modified UUCG hairpin loops
    Symposium Series 1999, Vol. 2, pp. 298–301 [Abstract]
    Published online 2016-05-08 23:33:16
  • Marek Kwiatkowski, Simon Fredriksson, Anders Isaksson, Mats Nilsson and Ulf Landegren
    In situ reversal of oligonucleotide orientation
    Symposium Series 1999, Vol. 2, pp. 213–213 [Abstract]
    Published online 2016-05-08 23:30:12
  • Uwe Parsch and Joachim W. Engels
    Calculation of thermodynamic data from UV melting curves of triple helical nucleic acids: A comparison of methods
    Symposium Series 1999, Vol. 2, pp. 15–21 [Abstract]
    Published online 2016-05-08 20:40:02
  • Jörg Parsch and Joachim W. Engels
    C–F···H–C hydrogen bonds in crystals of fluorobenzene ribonucleosides
    Symposium Series 1999, Vol. 2, pp. 11–14 [Abstract]
    Published online 2016-05-08 20:39:56
  • Aleksandra Živković, Jan W. Bats and Joachim W. Engels
    Crystal structures of fluoro- and chloro-modified benzene-nucleosides
    Symposium Series 2002, Vol. 5, pp. 396–398 [Abstract]
    Published online 2016-01-25 20:52:16
  • Nelly Piton, Frédéric Godde and Joachim W. Engels
    Determination of RNA tertiary structure by advanced electron paramagnetic resonance spectroscopy (EPR)
    Symposium Series 2002, Vol. 5, pp. 381–382 [Abstract]
    Published online 2016-01-25 20:51:44
  • Astrid E. Klöpffer and Joachim W. Engels
    Universal fluorinated nucleobases: Their effect on the catalytic activity of ribozymes
    Symposium Series 2002, Vol. 5, pp. 348–351 [Abstract]
    Published online 2016-01-25 20:50:43
  • Kerstin Jahn-Hofmann and Joachim W. Engels
    A new concept for DNA-arrays
    Symposium Series 2002, Vol. 5, pp. 335–337 [Abstract]
    Published online 2016-01-25 20:42:46
  • Joachim W. Engels, Thomas J. Lehmann, Jörg Parsch and Thorsten Strube
    Fluorine substituted DNA and RNA
    Symposium Series 2002, Vol. 5, pp. 245–250 [Abstract]
    Published online 2016-01-25 20:40:52
  • Stefan Amberg and Joachim W. Engels
    Synthesis, properties and determination of the configuration of arylpropyl backbone modified oligodeoxynucleotides
    Symposium Series 2002, Vol. 5, pp. 225–229 [Abstract]
    Published online 2016-01-25 20:40:31
  • Jelena Božilović, Jan W. Bats and Joachim W. Engels
    Synthesis and crystal structures of fluorinated indols as RNA analogues
    Symposium Series 2005, Vol. 7, pp. 385–386 [Abstract]
    Published online 2015-11-08 11:55:55
  • Andrey Semenyuk, András Földesi, Tommy Johansson, Camilla Estmer Nilsson, Mathias Brännvall, Leif Kirsebum and Marek Kwiatkowski
    Reliable method for RNA synthesis using t-butyldithiomethyl (DTM) group for the 2'-hydroxyl protection
    Symposium Series 2005, Vol. 7, pp. 379–380 [Abstract]
    Published online 2015-11-08 11:55:46
  • Aleksandra Živković and Joachim W. Engels
    Fluorinated benzenes and benzimidazoles as RNA analogues
    Symposium Series 2005, Vol. 7, pp. 271–275 [Abstract]
    Published online 2015-11-08 11:53:48
  • Agnieszka B. Olejniczak, Błażej Wojtczak, Marzena Przepiórkiewicz, Marek Kwiatkowski and Zbigniew J. Lesnikowski
    Nucleosides and their phosphates modified with dicarba-closo-dodecaborane (–C2B10H11) at 2'-position
    Symposium Series 2005, Vol. 7, pp. 239–243 [Abstract]
    Published online 2015-11-08 11:53:06
  • Gerda Wittel, Ping Gu and Joachim W. Engels
    Synthesis and activity of C-analogues for immune stimulating CpG-oligodeoxynucleotides
    Symposium Series 2005, Vol. 7, pp. 493–494 [Abstract]
    Published online 2015-11-08 11:49:35
  • Lena Wicke and Joachim W. Engels
    Synthesis of 6-substituted quinolone nucleosides as potential HIV integrase inhibitors
    Symposium Series 2008, Vol. 10, pp. 473–475 [Abstract]
    Published online 2015-10-30 18:45:41
  • Angelika Keller and Joachim W. Engels
    Synthesis of 3'-O-cyanoethyl-2'-deoxythymidine-5'-monophosphate and its use for the sequencing-by-synthesis technology
    Symposium Series 2008, Vol. 10, pp. 376–377 [Abstract]
    Published online 2015-10-30 18:42:36
  • Jamal Krim, Bouchra Sillahi, Moha Taourirte, Said Eddarir and Joachim W. Engels*
    Synthesis and antibacterial activity of unsaturated pyrimidine carboacyclonucleoside analogues
    2011, Vol. 76, Issue 11, pp. 1299–1305 [Abstract]
  • Martina M. Adams, Jan W. Bats, Nadja V. Nikolaus, Myriam Witvrouw, Zeger Debyser and Joachim W. Engels*
    Microwave-Assisted Synthesis of Fluoroquinolones and Their Nucleosides as Inhibitors of HIV Integrase
    2006, Vol. 71, Issue 7, pp. 978–990 [Abstract]
  • Marek Kwiatkowski, Mats Nilsson and Ulf Landegren
    A support for synthesis of full-length oligonucleotides
    1996, Vol. 61, Special Issue, pp. S307–S310 [Abstract]
  • Markus Schweitzer, Wendelin Samstag and Joachim W. Engels
    Synthesis and characteristics of a self-complementary tetramer d(CGCG) with methylphosphonate linkages of defined stereochemistry
    1996, Vol. 61, Special Issue, pp. S213–S216 [Abstract]