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Collect. Czech. Chem. Commun. 2009, 74, 515-534
https://doi.org/10.1135/cccc2008183
Published online 2009-03-18 11:47:05

Synthesis of 3′-O-(2-cyanoethyl)-2′-deoxythymidine-5′-phosphate as a model compound for evaluation of cyanoethyl cleavage

Angelika C. Kellera,*, Saulius Servab, Diana C. Knappa, Marek Kwiatkowskic and Joachim W. Engelsa

a Institut für Organische Chemie und Chemische Biologie, J. W. Goethe Universität Frankfurt am Main, Max-von-Laue Str. 7, 60438 Frankfurt am Main, Germany
b Fermentas UAB, V. Graiciuno 8, 02241 Vilnius, Lithuania
c Oligovation AB, Dag Hammarskjölds väg 32B, Uppsala Science Park, 751 83 Uppsala, Sweden

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  • Knapp Diana C., Serva Saulius, D'Onofrio Jennifer, Keller Angelika, Lubys Arvydas, Kurg Ants, Remm Maido, Engels Joachim W.: Fluoride-Cleavable, Fluorescently Labelled Reversible Terminators: Synthesis and Use in Primer Extension. Chem Eur J 2011, 17, 2903. <https://doi.org/10.1002/chem.201001952>
  • Rodríguez-Pérez Tatiana, Fernández Susana, Martínez-Montero Saúl, González-García Tania, Sanghvi Yogesh S., Gotor Vicente, Ferrero Miguel: Chemoenzymatic Synthesis of 3′-O-Acetal-Protected 2′-Deoxynucleosides as Building Blocks for Nucleic Acid Chemistry. Eur. J. Org. Chem. 2010, 2010, 1736. <https://doi.org/10.1002/ejoc.200901428>
  • Keller Angelika C., Serva Saulius, Knapp Diana C., Kwiatkowski Marek, Engels Joachim W.: ChemInform Abstract: Synthesis of 3′-O-(2-Cyanoethyl)-2′-deoxythymidine-5′-phosphate as a Model Compound for Evaluation of Cyanoethyl Cleavage. ChemInform 2009, 40. <https://doi.org/10.1002/chin.200933204>