Collect. Czech. Chem. Commun. 2007, 72, 334-346

Lignan Glucosides and Serotonin Phenylpropanoids from the Seeds of Leuzea carthamoides

Juraj Harmatha*, Miloš Buděšínský, Karel Vokáč, Milan Pavlík, Karel Grüner and Věra Laudová

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic


Two lignan glucosides, the known tracheloside and the new carthamoside, together with their two known aglycones, trachelogenin and (7E,8'S)-7,8-didehydroarctigenin (cf. cartha- mogenin), were isolated from the seeds of Leuzea carthamoides. Additional four phenylpropanoid derivatives of tryptamine, the E and Z isomers of N-feruloylserotonin and N-isoferuloylserotonin, were also isolated and identified. Their structure determination and identification were performed by spectroscopic, mainly NMR analysis.

Keywords: Leuzea carthamoides; Asteraceae; Lignans; Phenylpropanoids; Tracheloside; Carthamoside; N-Feruloylserotonin; N-Isoferuloylserotonin; Glycosides; Natural compounds.

References: 45 live references.